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Recognition of Bipolar Disorder Type I Before the First Manic Episode: Challenges and Developments
Physicians can miss the diagnosis of bipolar disorder (BD) for years among symptomatic patients. The current review provides insight into how to identify patients with BD before their first manic episode.
July 31, 2013
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Continuous Dopaminergic Delivery to Minimize Motor Complications in Parkinson’s Disease
Continuous dopaminergic delivery reduces motor complications in patients with advanced Parkinson disease and may prevent them in patients with mild Parkinson disease, based on a review of clinical strategies.
May 31, 2013
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Lessons Learned in the Abuse of Pain-Relief Medication: A Focus on Health Care Costs
Thousands of Americans die each year from prescription opioid abuse. What can be done to combat this increasing public health problem? The current review provides answers.
April 29, 2013
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Pseudoprogression After Glioma Therapy: A Comprehensive Review
Pseudoprogression of gliomas occurs among nearly 20% of patients receiving current treatment. What does this mean in terms of patient management, and what can be done to better differentiate true progression of gliomas from pseudoprogression? The current review provides answers.
April 02, 2013
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Safety of Disease-Modifying Drugs for Multiple Sclerosis in Pregnancy
Women with MS should avoid disease-modifying drugs (DMDs) during pregnancy and lactation, based on a review summarizing recent data and recommendations regarding the safety of interferon-beta, glatiramer acetate, and other DMDs.Women with MS should avoid disease-modifying drugs (DMDs) during pregnancy and lactation, based on a review summarizing recent data and recommendations regarding the safety
March 01, 2013
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Augmentation Strategies in Obsessive-Compulsive Disorder
A review shows that the best evidence for use of augmentation strategies in patients with OCD poorly responsive to SSRI treatment is for use of antipsychotics and for cognitive-behavior therapy.
January 30, 2013
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Treatment of Myoclonic Seizures
Valproate and some benzodiazepines are often used to treat myoclonic seizures, and some newer antiepileptic drugs may be effective, but some myoclonic epilepsies are refractory to treatment.
December 13, 2012
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Neurophysiological Assessment of Painful Neuropathies
To characterize painful neuropathies, clinicians should use neurophysiological testing to determine the features of the lesion causing pain rather than the feeling of pain itself.
December 12, 2012
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Chemotherapy: What Is Its Role In Meningioma?
For inoperable meningiomas or those tumors which recur or progress on standard therapy, cytotoxic, biologic, hormonal, and/or targeted molecular agents may be helpful.
October 19, 2012
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Neurodegeneration in Multiple Sclerosis: Novel Treatment Strategies
Neuronal inflammation resulting in neuronal injury plays a key role in determining long-term disability in multiple sclerosis and may be a good therapeutic target.
October 05, 2012
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Issues and Controversies Surrounding the Diagnosis and Treatment of Social Anxiety Disorder
Social anxiety disorder may be underrecognized, underdiagnosed, and undertreated, with controversy surrounding optimal diagnosis and treatment.
September 24, 2012
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Internet-Based Psychological Treatments for Depression
Internet-based psychological treatments are effective and offer a useful treatment option as an alternative to face-to-face psychological treatments and medication.
August 02, 2012
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Second-Generation Antiepileptic Drugs and Pregnancy: A Guide for Clinicians
Prescribing antiepileptic drugs to pregnant women requires weighing potential fetal adverse effects against the risks of uncontrolled maternal seizures, which is facilitated by recent scientific data.
May 31, 2012
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Identification and Management of Pain Medication Abuse and Misuse: Current State and Future Directions
Managing chronic pain patients with long-term opioid therapy while minimizing abuse and misuse is still challenging.
May 01, 2012
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Psychostimulants for ADHD-Like Symptoms in Individuals With Autism Spectrum Disorders
Findings of a literature review suggest that psychostimulants may be effective for ADHD-like symptoms in individuals with autism spectrum disorder.
March 26, 2012
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Prevalence, Clinical Features, and Potential Therapies for Fibromyalgia in Primary Headaches
Chronic migraine and tension headache have a high frequency of comorbidity with fibromyalgia, according to a review of prevalence, clinical features, and treatments of these comorbid conditions.
February 24, 2012
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Direct Thrombin Inhibitors and Factor Xa Inhibitors in Patients With Cerebrovascular Disease
In the near future, direct thrombin inhibitors and factor Xa inhibitors are likely to replace warfarin for long-term anticoagulation in selected patients with nonvalvular atrial fibrillation.
January 30, 2012
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A "Family Affair"? The Impact of Family Psychoeducational Interventions on Depression
Studies of family psychoeducational interventions on major depression are few and limited, but comprehensive management of unipolar major depression should include these interventions.
December 09, 2011
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Memory Problems in Dementia: Adaptation and Coping Strategies and Psychosocial Treatments
Pharmacotherapy, psychosocial treatments (eg, cognitive rehabilitation, cognitive stimulation therapy, and movement therapy), and coping strategies may all help manage memory problems in dementia.
November 17, 2011
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Distinguishing Alzheimer Disease From Other Major Forms of Dementia
Alzheimer disease encompasses a broad spectrum from preclinical, to mild cognitive impairment, to AD dementia; diagnosis requires AD biomarkers.
October 20, 2011
