-
Unintended Pregnancy During Radiotherapy for Cancer
Some women undergoing radiation therapy for cancer also have an early pregnancy. This is often a distressing situation that requires good counseling on the part of the physician. The current review examines the consequences of radiation therapy during pregnancy.
March 01, 2009
-
A Case of Prolonged Disease-Free Survival in a Patient With Choroidal Metastasis From Breast Cancer
Six years after lumpectomy, lymph-node dissection, and radiation therapy for ductal carcinoma of the right breast, this patient presented with increasingly blurred vision. Is there a connection?
December 11, 2008
-
Complete Response of Stage IV Anal Mucosal Melanoma Expressing KIT Val560Asp to the Multikinase Inhibitor Sorafenib
Adjuvant therapy with targeted kinase inhibitors may offer new hope for patients with anal mucosal melanoma. The current case study and review highlight this exciting potential treatment.
December 01, 2008
-
Noninvasive Detection of Therapeutic Cytolytic T Cells With 18F-FHBG PET in a Patient With Glioma
Adoptive cellular gene immunotherapy is a developing technology that may offer new hope to patients with cancer. The current case study and discussion describe the application of this treatment to a patient with glioblastoma mulitforme.
November 19, 2008
-
Treatment of Diffuse Large B-cell Lymphoma of The Liver With Yttrium-90 Microsphere Embolization
New technologies offer hope for patients with lymphoma who have few therapeutic options. The current case and review highlight this treatment.
November 01, 2008
-
Strategies for Discovering Novel Cancer Biomarkers Through Utilization of Emerging Technologies
Cancer biomarkers are used to help diagnose and manage patients, and new technologies promise to increase the application of cancer biomarkers in the clinical setting. The current review highlights advances in the field of cancer biomarkers.
October 01, 2008
-
CTLA-4 Blockade With Ipilimumab Induces Significant Clinical Benefit in a Female With Melanoma Metastases to the CNS
Although the survival rate of melanoma with metastases to the central nervous system is dismal, new medications, such as ipilimumab, offer hope to these patients.
September 01, 2008
-
Audiologic and Radiographic Response of NF2-related Vestibular Schwannoma to Erlotinib Therapy
Neurofibromatosis type 2 (NF2) is a tumor suppressor syndrome characterized by schwannomas, meningiomas and spinal cord gliomas. The clinical features, diagnostic criteria, presentations and treatment of NF2 are reviewed in this case.
August 01, 2008
-
Biomarkers of Angiogenesis for the Development of Antiangiogenic Therapies in Oncology: Tools or Decorations?
Four antiangiogenesis drugs have been approved for human use in solid tumors but no validated biomarkers are available for routine clinical use. The roles and challenges of developing biomarkers of angiogenesis are reviewed.
July 01, 2008
-
Angiogenesis as a Strategic Target for Ovarian Cancer Therapy
Treatments that target angiogenesis will play an increasing role in the management of ovarian cancer. The current article reviews the latest research into these agents while also describing directions for future research.
April 01, 2008
-
Therapy Insight: Anthracyclines and Trastuzumab - The Optimal Management of Cardiotoxic Side Effects
Trastuzumab may significantly improve survival among women with advanced breast cancer, but there are concerns about cardiotoxicity associated with this targeted therapy. The current analysis examines this issue and means to prevent cardiac events among women receiving trastuzumab.
March 25, 2008
-
Drug Insight: Gastrointestinal and Hepatic Adverse Effects of Molecular-Targeted Agents in Cancer Therapy
Molecular targeted therapy has emerged as an important modality for chemotherapy, but these medications also promote gastrointestinal side effects. The current review examines these complications and how to manage them effectively.
March 17, 2008
-
Advances In the Systemic Therapy of Malignant Pleural Mesothelioma
Rates of malignant pleural mesothelioma are expected to rise, and new research has highlighted the best means to use systemic therapy to improve the course of this disease. The current article reviews this research and focuses on future directions for the care of patients with malignant pleural mesothelioma.
March 01, 2008
-
The Etiology and Management of Intractable Breathlessness in Patients With Advanced Cancer: A Systematic Review of Pharmacological Therapy
Breathlessness is common in advanced cancer, but many physicians are uncertain of how to manage this symptom. The current review examines the pathophysiology and management of breathlessness in cancer.
February 01, 2008
-
Human Papillomavirus in Cervical and Head-and-Neck Cancer
Human papillomavirus (HPV) is usually thought of as the main causative agent of cervical cancer, but new evidence suggests that HPV can promote head and neck cancer.
January 01, 2008
-
Active Surveillance for Favorable-risk Prostate Cancer: Who, How and Why?
December 01, 2007
-
Will Focal Therapy Become a Standard of Care for Men With Localized Prostate Cancer?
November 01, 2007
-
Individualized Preventive and Therapeutic Management of Hereditary Breast Ovarian Cancer Syndrome
null
October 01, 2007
