The goal of treatment in patients with epileptic seizures is to achieve a seizure-free status with tolerable adverse effects. Despite advances in anti-seizure medications (ASMs) over the past 25 years, more than a third of patients with epilepsy continue to experience uncontrolled seizures. In addition, seizure control with subsequent ASMs diminishes. By the time a third and fourth ASM are tried, the rate of seizure freedom is 1.0% and 0.4%, respectively. These resources will provide critical tools that clinicians need to assess, diagnose, and incorporate strategies to improve the likelihood of seizure freedom in people with focal seizures.
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