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From Medscape Education Infectious Diseases

Ask the Experts: Advances in Managing the Heavily Treatment-Experienced Patient With HIV

About This Series

Individuals with HIV who are heavily treatment-experienced with viremia and resistance -- whether they are older patients who sequenced through many nonsuppressive regimens, or adolescents/young adults who have survived perinatal HIV acquisition with limited antiretroviral agents available to them and despite adherence issues -- have limited treatment options, even in the current era with 7 classes of active drugs. These patients require highly individualized care from or in consultation with a specialist with experience evaluating and managing this niche population to select a regimen with at least 2 active drugs from at least 2 classes. In this collection of activities, leading experts in HIV medicine explore these challenges and offer practical guidance on how to evaluate patients in order to select for them a fully active antiretroviral regimen.

Polling Question

Steering Committee


David A. Wohl, MD (Chair)

Professor of Medicine
Division of Infectious Diseases
Site Leader, HIV Prevention and Treatment Clinical Trials Unit at Chapel Hill
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina

Richard A. Elion, MD

Associate Clinical Professor
Department of Clinical Investigations
Whitman-Walker Health
Washington, D.C.

Mehri S. McKellar, MD

Associate Professor of Medicine
Duke University School of Medicine
Durham, North Carolina

Paul E. Sax, MD

Professor of Medicine
Harvard Medical School
Clinical Director of the Division of Infectious Diseases
Brigham and Women's Hospital
Boston, Massachusetts