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Talking With Your Patients About Biomarker Testing for Alzheimer’s Disease

  • Authors: Sharon Cohen, MD, FRCPC
  • CME / ABIM MOC Released: 10/26/2023
  • Valid for credit through: 10/26/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 0.25 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.25 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for neurologists, primary care physicians, and psychiatrists.

The goal of this activity is for learners to be better able to utilize biomarkers for Alzheimer's disease in clinical settings and to explain the use of biomarkers to patients/caregivers.

Upon completion of this activity, participants will:

  • Explain the strengths and weaknesses of cerebrospinal fluid (CSF) biomarker testing
  • Utilize CSF biomarker tests in patients with cognitive impairment to facilitate timely and differential diagnosis


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Medscape policies. Others involved in the planning of this activity have no relevant financial relationships.


  • Sharon Cohen, MD, FRCPC

    Medical Director
    Toronto Memory Program
    Toronto, Ontario, Canada


    Sharon Cohen, MD, FRCPC, has the following relevant financial relationships: 
    Consultant or advisor for: Alnylam Pharmaceuticals, Inc; Biogen; Biohaven, Ltd.; Bristol Myers Squibb Company; Cassava Sciences, Inc.; Cognivue, Inc.; Cogstate Ltd.; Eisai Inc.; Eli Lilly and Company; INmuneBIO; H. Lundbeck A/S.; Novo Nordisk; Parexel; ProMIS Neurosciences, Inc.; Prothena; RetiSpec Inc.; Roche; SciNeuro Pharmaceuticals; Seq Biomarque
    Research funding from: AbbVie Inc.; AgeneBio, Inc.; Alector, Inc.; Alnylam Pharmaceuticals, Inc; Alzheon, Inc.; Anavex Life Sciences Corp.; Biogen; Cassava Sciences; Eisai Inc.; Eli Lilly and Company, Janssen; Novo Nordisk; RetiSpec Inc.; Roche; UCB Biopharma


  • Frances McFarland, PhD, MA

    Medical Education Director, Medscape, LLC


    Frances McFarland, PhD, MA, has no relevant financial relationships.

Compliance Reviewer

  • Amanda Jett, PharmD, BCACP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Amanda Jett, PharmD, BCACP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements


Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.25 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    College of Family Physicians of Canada Mainpro+® participants may claim certified credits for any AMA PRA Category 1 credit(s)™, up to a maximum of 50 credits per five-year cycle. Any additional credits are eligible as non-certified credits. College of Family Physicians of Canada (CFPC) members must log into Mainpro+® to claim this activity.

    Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


Talking With Your Patients About Biomarker Testing for Alzheimer’s Disease

Authors: Sharon Cohen, MD, FRCPCFaculty and Disclosures

CME / ABIM MOC Released: 10/26/2023

Valid for credit through: 10/26/2024, 11:59 PM EST


Lisa, a 72-year-old woman, has been diagnosed with mild cognitive impairment and is visiting a specialist for further evaluation.

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