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Targeting B7-H3 In Solid Tumors: Understanding the Rationale and the Latest Developments

  • Authors: Elena Garralda Cabanas, MD 
  • CME / ABIM MOC Released: 10/9/2023
  • Valid for credit through: 10/9/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 0.25 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.25 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for oncologists and pathologists.

The goal of this activity is for learners to be better able to understand the rationale behind targeting B7-H3 in solid tumors.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Rationale for targeting B7-H3 in advanced solid tumors
    • Latest clinical trial data investigating therapies targeting B7-H3 in solid tumors
  • Demonstrate greater confidence in their ability to
    • Understand the clinical implications of the latest clinical trial data


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


  • Elena Garralda Cabanas, MD

    Medical Oncologist
    Early Drug Development
    Vall d'Hebron Institute of Oncology
    Barcelona, Spain


    Elena Garralda Cabanas, MD, has the following relevant financial relationships:
    Consultant or advisor for: Anaveon; Boehringer Ingelheim Pharmaceuticals, Inc.; Ellipses Pharma; F-Star Therapeutics; Hengrui; Incyte Corporation; Janssen Global Services; MabDiscovery; Roche; Sanofi; Seagen Inc; Thermo Fisher Scientific Inc.
    Speaker or member of speakers bureau for: Eli Lilly and Company; Merck Sharp & Dohme; Novartis; Roche; Seagen Inc.; Thermo Fisher Scientific Inc.
    Research funding from: AstraZeneca Pharmaceuticals LP; BeiGene (Beijing) Co., Ltd; Janssen Biotech, Inc.; Novartis; Roche; Taiho Pharmaceutical Co., Ltd.; Thermo Fisher Scientific Inc.


  • Megan Cannon, PhD

    Medical Education Director, WebMD Global, LLC 


    Megan Cannon, PhD, has no relevant financial relationships. 

  • Eloise Ballard, PhD

    Scientific Content Manager, WebMD Global, LLC 


    Eloise Ballard, PhD, has no relevant financial relationships. 

Compliance Reviewer

  • Amanda Jett, PharmD, BCACP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Amanda Jett, PharmD, BCACP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements


Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.25 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    College of Family Physicians of Canada Mainpro+® participants may claim certified credits for any AMA PRA Category 1 credit(s)™, up to a maximum of 50 credits per five-year cycle. Any additional credits are eligible as non-certified credits. College of Family Physicians of Canada (CFPC) members must log into Mainpro+® to claim this activity.

    Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

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For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


Targeting B7-H3 In Solid Tumors: Understanding the Rationale and the Latest Developments

Authors: Elena Garralda Cabanas, MD Faculty and Disclosures

CME / ABIM MOC Released: 10/9/2023

Valid for credit through: 10/9/2024, 11:59 PM EST


Educational Impact Challenge

Please answer the questions below to self-assess your knowledge. Answering these questions again after the activity will allow you to see what you learned. 

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