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CME / ABIM MOC / CE

New Hope for NRAS/BRAF-Mutated Advanced Solid Tumors: The Evaluation of Pan-RAF Inhibitors

  • Authors: Alexander Spira, MD, PhD, FACP
  • CME / ABIM MOC / CE Released: 8/2/2023
  • Valid for credit through: 8/2/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 0.25 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.25 ABIM MOC points

    Nurses - 0.25 ANCC Contact Hour(s) (0.25 contact hours are in the area of pharmacology)

    Pharmacists - 0.25 Knowledge-based ACPE (0.025 CEUs)

    IPCE - 0.25 Interprofessional Continuing Education (IPCE) credit

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for oncologists, dermatologists, pathologists, nurses, pharmacists, and other members of the oncology care team.

The goal of this activity is for learners to be better able to recognize the role of pan-RAF kinase inhibitors in the care of patients with NRAS/BRAF-mutated advanced solid tumors.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Characteristics of NRAS/BRAF mutations in advanced solid tumors
    • Clinical trial data evaluating pan-RAF inhibitors for the treatment of advanced solid tumors
  • Demonstrate greater confidence in their ability to
    • Evaluate clinical trial data on pan-RAF inhibitors for the treatment of advanced solid tumors


Disclosures

Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Medscape policies. Others involved in the planning of this activity have no relevant financial relationships.


Faculty

  • Alexander Spira, MD, PhD, FACP

    Medical Oncologist
    Co-Director, Virginia Cancer Specialists Research Institute
    Clinical Director, NEXT Oncology Fairfax, Virginia

    Disclosures

    Alexander Spira, MD, PhD, FACP, has the following relevant financial relationships:
    Consultant or advisor for: Amgen Inc.; Array BioPharma; AstraZeneca/MedImmune Inc.; Bayer; Blueprint Medicines; Bristol Myers Squibb Company; CytomX Therapeutics; Daiichi Sankyo, Inc./AstraZeneca; Gritstone Bio; Gritstone Oncology; Incyte Corporation; Janssen Research & Development, LLC; Jazz Pharmaceuticals, Inc.; Merck; Mersana Therapeutics; Mirati Therapeutics; Novartis; Regeneron Pharmaceuticals, Inc.; Takeda Pharmaceuticals
    Research funding from: AbbVie Inc.; ADCT; Alkermes, Inc.; Amgen Inc.; Arch Therapeutics; Astellas Pharma, Inc.; Astex Pharmaceuticals; AstraZeneca; Blueprint Medicines; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol Myers Squibb Company; CytomX Therapeutics; Daiichi Sankyo, Inc.; Gritstone; Ignyta Inc.; Incyte Corporation; Janssen Oncology; LAM Therapeutics; Loxo Oncology; MacroGenics; MedImmune Inc.; Mersana Therapeutics; Mirati Therapeutics; NewLink Genetics; Novartis; Plexxikon Inc.; Regeneron Pharmaceuticals, Inc.; Revolution Medicines; Roche; Rubius; Synthekine; Takeda Pharmaceuticals; Trovagene
    Owns stock (publicly traded) in: Lilly

Editor

  • Deborah Middleton, MS

    Senior Medical Education Director, WebMD Global, LLC

    Disclosures

    Deborah Middleton, MS, has no relevant financial relationships.

Compliance Reviewer/Nurse Planner

  • Leigh Schmidt, MSN, RN, CNE, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Leigh Schmidt, MSN, RN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.


Accreditation Statements

Medscape

Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

IPCE

This activity was planned by and for the healthcare team, and learners will receive 0.25 Interprofessional Continuing Education (IPCE) credit for learning and change.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.25 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    College of Family Physicians of Canada Mainpro+® participants may claim certified credits for any AMA PRA Category 1 credit(s)™, up to a maximum of 50 credits per five-year cycle. Any additional credits are eligible as non-certified credits. College of Family Physicians of Canada (CFPC) members must log into Mainpro+® to claim this activity.

    Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program. 

    Contact This Provider

    For Nurses

  • Awarded 0.25 contact hour(s) of nursing continuing professional development for RNs and APNs; 0.25 contact hours are in the area of pharmacology.

    Contact This Provider

    For Pharmacists

  • Medscape designates this continuing education activity for 0.25 contact hour(s) (0.025 CEUs) (Universal Activity Number: JA0007105-0000-23-318-H01-P).

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / ABIM MOC / CE

New Hope for NRAS/BRAF-Mutated Advanced Solid Tumors: The Evaluation of Pan-RAF Inhibitors

Authors: Alexander Spira, MD, PhD, FACPFaculty and Disclosures

CME / ABIM MOC / CE Released: 8/2/2023

Valid for credit through: 8/2/2024, 11:59 PM EST

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Learning Feedback Questions

Please answer the questions below to self-assess your knowledge. Answering these questions again after the activity will allow you to see what you learned.

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