Thursday, November 30, 2023
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All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.
Chair, Lymphoma Tumour Group
BC Cancer Centre for Lymphoid Cancer
Clinical Professor of Medicine
Division of Medical Oncology
University of British Columbia
Vancouver, British Columbia, Canada
This activity has been peer reviewed and the reviewer has no relevant financial relationships.
Physicians - maximum of 1.00 AMA PRA Category 1 Credit(s)™
ABIM Diplomates - maximum of 1.00 ABIM MOC points
This activity is intended for hematology/oncology specialists.
The goal of this activity is for learners to be better able to apply recent data regarding newer therapies for R/R follicular lymphoma and R/R diffuse large B-cell lymphoma to the management of these diseases.
Upon completion of this activity, participants will:
Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.
All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.
Chair, Lymphoma Tumour Group
BC Cancer Centre for Lymphoid Cancer
Clinical Professor of Medicine
Division of Medical Oncology
University of British Columbia
Vancouver, British Columbia, Canada
This activity has been peer reviewed and the reviewer has no relevant financial relationships.
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.
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CME / ABIM MOC Released: 6/30/2023
Valid for credit through: 6/30/2024, 11:59 PM EST
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The following cases are modeled on the interactive grand rounds approach. The questions within the activity are designed to test your current knowledge. After each question, you will be able to see whether you answered correctly and read evidence-based information that supports the most appropriate answer choice. The questions are designed to challenge you; you will not be penalized for answering the questions incorrectly. At the end of the activity, there will be a short post-test assessment based on the material presented.
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Alice is a 74-year-old retired seamstress who has been married for 48 years and has 2 adult children and 7 grandchildren who live nearby. She is active in her community and helps care for her grandchildren. She has a history of hypertension and moderate arthritis.
Five years ago, Alice was diagnosed with follicular lymphoma (FL) and treated with bendamustine plus obinutuzumab. She achieved a complete response (CR) and did well following completion of therapy. At her 4-year follow-up, positron emission tomography/computed tomography (PET/CT) showed disease progression and she began second-line therapy with lenalidomide plus rituximab. Imaging showed a very good partial response (VGPR). She now comes in 24 months later for routine follow-up and reports moderate swelling in her neck and groin. Her workup is summarized in Table 1.
Table 1. Alice's Workup
| Results | |
|---|---|
| Demographics/patient information |
|
| Personal and family medical history |
|
| Physical examination |
|
| CBC |
|
| PET/CT |
|
BP, blood pressure; CBC, complete blood count; ECOG PS, Eastern Cooperative Oncology Group performance status; FDG, 18F-fluorodeoxyglucose; IU, international unit; LDH, lactate dehydrogenase; RBC, red blood cell; SUV, standardized uptake value; ULN, upper limit of normal; WBC, white blood cell.
