Physicians - maximum of 1.50 AMA PRA Category 1 Credit(s)™
Neurologists, neuroscientists, nurse practitioners, neuroscience nurses and other healthcare professionals involved in the clinical study, management, and care of patients with multiple sclerosis.
This CME activity will highlight the importance of targeting pathways of disease progression in early multiple sclerosis (MS), including the developing role of Bruton’s tyrosine kinase (BTK) inhibitors. This class of agents disarms both the peripheral (i.e., lymphocyte) and central, chronically activated (i.e., microglia/macrophage) cells that are dysregulated in MS. By targeting multiple biological processes that include B-cell and macrophage activation, the BTK pathway is under clinical investigation to determine its potential role in mitigating disease activity across the spectrum of MS.
The educational goals of this activity are to equip neurologists with the knowledge and strategies to evaluate the potential role of this class of emerging agents in MS, as well as to assess imminent topline results from Phase III clinical trials, and to better predict the role of BTK inhibition within the current armamentarium of disease modifying therapies. To do so, clinicians will need to better understand the potential targets for BTK inhibition, as well as to analyze the current preclinical and clinical trial data, and to anticipate how these potential agents may change the current treatment paradigm.
Upon completion of this activity, participants will be able to:
Letters & Sciences and PACE require planners, faculty, and others who are in positions to control the content of this activity to disclose all financial relationships they may have with ineligible companies. All relevant financial relationships are thoroughly vetted and mitigated according to the providers' policies. Letters & Sciences and PACE are committed to providing learners with high-quality accredited CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.
Faculty
All identified real or perceived COI have been thoroughly vetted and resolved according to the providers’ policies. Letters & Sciences and PACE are committed to providing learners with high quality accredited activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.
Jointly provided by Letters & Sciences and Partners for Advancing Clinical Education (PACE).
For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]
There are no fees for participating in or receiving credit for this online educational activity. For information on applicability
and acceptance of continuing education credit for this activity, please consult your professional licensing board.
This activity is designed to be completed within the time designated on the title page; physicians should claim only those
credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the
activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 80% on the post-test.
Follow these steps to earn CME/CE credit*:
You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it.
Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print
out the tally as well as the certificates from the CME/CE Tracker.
*The credit that you receive is based on your user profile.
CME Released: 6/30/2023
Valid for credit through: 6/30/2024, 11:59 PM EST
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Please answer the questions that appear during the activity: Choose an answer, scroll down, and click “Submit.” See responses, scroll down, and click “Continue.”