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CME

Hot Topics in Cardiovascular Disease: Can Cardiologists Do More to Improve Outcomes in People with Type 2 Diabetes?

  • Authors: Yehuda Handelsman, MD, FACP, FNLA, FASPC, MACE; Brendan Everett, MD, MPH
  • CME Released: 6/1/2023
  • Valid for credit through: 6/1/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 1.25 AMA PRA Category 1 Credit(s)™

    You Are Eligible For

    • Letter of Completion

Target Audience and Goal Statement

Cardiologists who are interested in reducing cardiovascular risk, particularly risk of atherosclerotic cardiovascular disease, in individuals with type 2 diabetes.

The cardiovascular (CV) benefits identified in CV outcomes trials (CVOTs) for glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have resulted in updated guidance from the American Diabetes Association and American Association of Clinical Endocrinology that advises use of GLP-1 RAs (or sodium glucose cotransporter 2 [SGLT2] inhibitors) in all people with or at high risk for atherosclerotic CV disease (ASCVD), regardless of glycated hemoglobin (A1C) or metformin use. The American College of Cardiology has recently released a similar recommendation in their 2020 Clinical Decision Pathway, while also calling on cardiologists to increase their involvement in screening for and treating type 2 diabetes (T2D). The cardioprotective effects of GLP-1 RAs have significantly altered the treatment landscape for people with T2D who have, or are high risk for, ASCVD, and it is critical that cardiologists are familiar with the CVOT data and prescribing recommendations for GLP-1 RAs, as well as factors that differentiate them from other glucose-lowering agents. The goal of this activity is to provide a comprehensive review of these agents and their clinical effects in order to help to increase confidence among cardiologists in integrating these therapies into practice and working with other clinicians and patients to develop treatment plans that offer the greatest chance of success.

Learning Objectives

Upon completion of this activity, participants will:

  1. Explain the critical role of cardiologists in improving CV outcomes in people with T2D
  2. Describe the impact of GLP-1 RAs and SGLT2 inhibitors on CV outcomes
  3. Discuss evidence-based recommendations for clinical use of GLP-1 RAs and SGLT2 inhibitors in people with CVD and T2D
  4. Describe the multiple extraglycemic effects of GLP-1 RAs, including intraclass differences
  5. Initiate GLP-1 RA therapy in appropriate patients and monitor for efficacy, tolerability, and safety
  6. Implement treatment approaches that reduce risk of secondary CVD in people with T2D


Disclosures

Disclosures

It is the policy of IMNE to ensure fair balance, independence, objectivity, and scientific rigor in all programming. All individuals involved in planning (eg, faculty, CME/CE provider staff, and educational partner staff) are expected to disclose any relevant financial relationships with ineligible companies over the past 24 months. It is also required that faculty identify and reference off-label products or investigational uses of pharmaceutical agents and medical devices.

Mitigation of Relevant Financial Interests

IMNE utilizes a peer review process to mitigate potential and actual conflicts of interest disclosed by all persons in a position to influence the planning process or content development of this educational activity. All peer reviewers are without relevant financial relationships. A copy of the mitigation worksheet is available by request from [email protected]


Faculty

  • Yehuda Handelsman, MD, FACP, FNLA, FASPC, MACE

    Medical Director & Principal Investigator
    Metabolic Institute of America
    Tarzana, California 

    Disclosures

    Yehuda Handelsman, MD, FACP, FNLA, FASPC, MACE, has the following relevant financial relationships: 
    Consultant or advisor for: Amarin; Amgen; Applied Therapeutics; Boehringer Ingelheim; Esperion Therapeutics; Merck; Merck-Pfizer; Novartis; Vertis.
    Speaker or member of speakers bureau for: Amarin; AstraZeneca; Merck; Novo Nordisk.
    Research funding from: Amgen; Applied Therapeutics; Novo Nordisk.

  • Brendan Everett, MD, MPH

    Preventive Cardiologist, Brigham and Women’s Hospital 
    Associate Professor, Medicine at Harvard Medical School
    Boston, Massachusetts

    Disclosures

    Brendan Everett, MD, MPH, has the following relevant financial relationships: 
    Consultant or advisor for: Eli Lilly and Company; Gilead Sciences; Ipsen Biopharmaceuticals; Janssen; Provention Bio; Sequana (spouse).
    Contracted researcher for: PCORI.
    Royalties from: UpToDate.

IMNE Staff

  • Amy Groves, BS (With Honors)

    Business Lead

    Disclosures

    Ms Groves has no relevant financial relationships.

  • Steve Weinman, MSc, RN

    Director of Accreditation
    ANCC Accredited Provider Program Director

    Disclosures

    Mr Weinman has no relevant financial relationships.

  • Michelle Fisher, BS

    Account Coordinator

    Disclosures

    Ms Fisher has no relevant financial relationships.

  • Ruth Wills, PhD

    Scientific Program Director 

    Disclosures

    Dr Wills has no relevant financial relationships.

  • Megan Widdows, MSc

    Medical Writer

    Disclosures

    Ms Widdows has no relevant financial relationships.

  • Leanne Patrick, BSc

    Senior Medical Writer

    Disclosures

    Ms Patrick has no relevant financial relationships.

CME Reviewer

  • Martin Quan, MD

    Disclosures

    Dr Quan has no relevant financial relationships.


Accreditation Statements

The Institute for Medical and Nursing Education

The Institute for Medical and Nursing Education, Inc. (IMNE), is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

    For Physicians

  • IMNE designates this enduring activity for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME

Hot Topics in Cardiovascular Disease: Can Cardiologists Do More to Improve Outcomes in People with Type 2 Diabetes?

Authors: Yehuda Handelsman, MD, FACP, FNLA, FASPC, MACE; Brendan Everett, MD, MPHFaculty and Disclosures

CME Released: 6/1/2023

Valid for credit through: 6/1/2024, 11:59 PM EST

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This CME activity was developed to be distributed on Medscape.org. The program is an online, enduring activity with videos led by expert faculty (1 endocrinologist and 1 cardiologist) considered to be key opinion leaders in type 2 diabetes and cardiology.

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