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General Principles for the Use of Disease-Modifying Therapies in Multiple Sclerosis

  • Authors: Patricia K. Coyle, MD, FAAN, FANA
  • CME Released: 5/10/2023
  • Valid for credit through: 5/10/2024
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  • Credits Available

    Physicians - maximum of 0.25 AMA PRA Category 1 Credit(s)™

    You Are Eligible For

    • Letter of Completion

Target Audience and Goal Statement

This activity is intended for neurologists (general neurologists and neurologists practicing in rural communities), primary care physicians, obstetricians/gynecologists, and other clinicians who treat patients with multiple sclerosis (MS).

The goal of this activity is for learners to be better able to consider clinical and prognostic factors in the selection of initial therapy for MS.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Goals of treatment in MS
    • Prognostic factors associated with MS
    • Clinical factors involved in selecting an initial therapy for the management of MS


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


  • Patricia K. Coyle, MD, FAAN, FANA

    Professor of Neurology
    Vice Chair for Academic Affairs
    Director, MS Comprehensive Care Center
    Stony Brook Renaissance School of Medicine
    Stony Brook, New York


    Patricia K. Coyle, MD, FAAN, FANA, has the following relevant financial relationships:
    Consultant or advisor for: Accordant; Biogen; Bristol Myers Squibb Company; GlaxoSmithKline; Horizon Therapeutics; Lilly; Mylan Laboratories, Inc.; Novartis; Sanofi Genzyme; TG Therapeutics, Inc.
    Contracted researcher for: Actelion Pharmaceuticals, Ltd; Alkermes, Inc.; Celgene Corporation; CorEvitas LLC; Genentech/Roche; MedDay Pharmaceuticals (former); Novartis; Sanofi Genzyme


  • Maya Khalaf, MSc

    Medical Education Director, WebMD Global, LLC


    Maya Khalaf, MSc, has no relevant financial relationships.

Compliance Reviewer

  • Amanda Jett, PharmD, BCACP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Amanda Jett, PharmD, BCACP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.25  AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    College of Family Physicians of Canada Mainpro+® participants may claim certified credits for any AMA PRA Category 1 credit(s)™, up to a maximum of 50 credits per five-year cycle. Any additional credits are eligible as non-certified credits. College of Family Physicians of Canada (CFPC) members must log into Mainpro+® to claim this activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


General Principles for the Use of Disease-Modifying Therapies in Multiple Sclerosis

Authors: Patricia K. Coyle, MD, FAAN, FANAFaculty and Disclosures

CME Released: 5/10/2023

Valid for credit through: 5/10/2024


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