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CME / ABIM MOC

Merging Established and Emerging Therapeutics in Rett Syndrome: Case Conversations

  • Authors: Alan K. Percy, MD; Jennifer Martelle Tu, MD, PhD; Eric Marsh, MD, PhD
  • CME / ABIM MOC Released: 4/14/2023
  • Valid for credit through: 4/14/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 0.50 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.50 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for neurologists, pediatricians, primary care physicians (PCPs), and other clinicians who treat patients with Rett syndrome.

The goal of this activity is for learners to be better able to develop an individualized treatment plan for patients diagnosed with Rett syndrome.

Upon completion of this activity, participants will:

  • Have greater competence related to
    • Selection of therapies to address specific symptoms associated with Rett syndrome
    • Identification of patients who are candidates for emerging therapies for the management of Rett syndrome
  • Demonstrate greater confidence in their ability to
    • Personalize the selection of treatments for the management of Rett syndrome


Disclosures

Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


Faculty

  • Alan K. Percy, MD

    Professor of Pediatrics, Neurology, Neurobiology, 
    Genetics, and Psychology-Emeritus
    Sarah Katherine Bateh Endowed Professorship 
    for Rett Syndrome-Emeritus 
    University of Alabama at Birmingham
    Birmingham, Alabama

    Disclosures

    Alan K. Percy, MD, has the following relevant financial relationships: 
    Consultant or advisor for: ACADIA Pharmaceuticals Inc.; Neurogene
    Contracted researcher for: ACADIA Pharmaceuticals Inc. 

  • Jennifer Martelle Tu, MD, PhD

    Associate Professor of Neurology 
    Director, Katie's Clinic for Rett Syndrome 
    UCSF Benioff Children's Hospitals Oakland 
    Oakland, California

    Disclosures

    Jennifer Martelle Tu, MD, PhD, has the following relevant financial relationships: 
    Owns stock (publicly traded) in: Stoke Therapeutics
     

  • Eric Marsh, MD, PhD

    ​Associate Professor of Neurology and Pediatrics
    ​Clinical Director, Orphan Disease Center
    ​Children's Hospital of Philadelphia
    ​University of Pennsylvania, Perelman School of Medicine
    ​Philadelphia, Pennsylvania​

    Disclosures

    Eric Marsh, MD, PhD, has the following relevant financial relationships:
    Consultant or advisor for: ​ACADIA Pharmaceuticals Inc.​
    Speaker or member of speakers bureau for: ​Marinus Pharmaceuticals, Inc. (former)​
    Research funding from: ​Curaleaf, Inc.​
    Contracted researcher for: ​ACADIA Pharmaceuticals Inc.; Epigenyx Pharmaceuticals; Marinus Pharmaceuticals, Inc.; Stoke Therapeutics; Takeda Pharmaceuticals; Zogenix, Inc.​ 

Editor

  • Pakinam Aboulsaoud, PharmD

    Senior Medical Education Director, Medscape, LLC

    Disclosures

    Pakinam Aboulsaoud, PharmD, has no relevant financial relationships.

Compliance Reviewer

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Stephanie Corder, ND, RN, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.


Accreditation Statements

Medscape

Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    The European Union of Medical Specialists (UEMS)-European Accreditation Council for Continuing Medical Education (EACCME) has an agreement of mutual recognition of continuing medical education (CME) credit with the American Medical Association (AMA). European physicians interested in converting AMA PRA Category 1 credit™ into European CME credit (ECMEC) should contact the UEMS (www.uems.eu).

    College of Family Physicians of Canada Mainpro+® participants may claim certified credits for any AMA PRA Category 1 credit(s)™, up to a maximum of 50 credits per five-year cycle. Any additional credits are eligible as non-certified credits. College of Family Physicians of Canada (CFPC) members must log into Mainpro+® to claim this activity.

    Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / ABIM MOC

Merging Established and Emerging Therapeutics in Rett Syndrome: Case Conversations

Authors: Alan K. Percy, MD; Jennifer Martelle Tu, MD, PhD; Eric Marsh, MD, PhDFaculty and Disclosures

CME / ABIM MOC Released: 4/14/2023

Valid for credit through: 4/14/2024, 11:59 PM EST

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Educational Impact Challenge

The goal of this activity is for learners to be better able to develop an individualized treatment plan for patients diagnosed with Rett syndrome.

Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.

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