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Navigating New Frontiers in Rhythm Control in Atrial Fibrillation: Real-World Patient Encounters

  • Authors: Peter R. Kowey, MD
  • CME / ABIM MOC Released: 3/28/2023
  • Valid for credit through: 3/28/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 0.25 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.25 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for cardiologists, primary care physicians, emergency medicine physicians, and other clinicians who care for patients with/at risk for atrial fibrillation (AF).

The goal of this activity is for learners to be better able to recognize and diagnose AF early in the disease course and to integrate appropriate treatment with anti-arrhythmic drugs (AADs) in real-world clinical scenarios.

Upon completion of this activity, participants will:

  • Have greater competence related to
    • Timely diagnosis of AF in accordance with the latest guideline-based screening recommendations
    • Selection of appropriate AADs for rhythm control in patients with AF in different clinical situations in accordance with the latest clinical evidence and practice guidelines
  • Have greater knowledge related to
    • The link between heart failure with preserved ejection fraction (HFpEF) and AF and patient outcomes
  • Demonstrate greater confidence in their ability to
    • Communicate with patients with AF about the benefits/risks of AADs for maintenance of sinus rhythm


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


  • Peter R. Kowey, MD

    Professor of Medicine and Clinical Pharmacology
    Thomas Jefferson University
    Emeritus Chief of Cardiovascular Diseases
    Lankenau Heart Institute
    Wynnewood, Pennsylvania


    Peter R. Kowey, MD, has the following relevant financial relationships:
    Consultant or advisor for: AbbVie Inc.; Acesion Pharma; Anthos Therapeutics; Daiichi Sankyo, Inc.; InCarda Therapeutics, Inc.; Johnson and Johnson; Medtronic, Inc.; Milestone Pharmaceuticals, Inc.; Sanofi


  • Asha P. Gupta, PharmD, RPh

    Medical Education Director, Medscape, LLC


    Asha P. Gupta, PharmD, RPh, has no relevant financial relationships.

Compliance Reviewer

  • Amanda Jett, PharmD, BCACP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Amanda Jett, PharmD, BCACP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements


Interprofessional Continuing Education

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    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.25 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    The European Union of Medical Specialists (UEMS)-European Accreditation Council for Continuing Medical Education (EACCME) has an agreement of mutual recognition of continuing medical education (CME) credit with the American Medical Association (AMA). European physicians interested in converting AMA PRA Category 1 credit™ into European CME credit (ECMEC) should contact the UEMS (

    College of Family Physicians of Canada Mainpro+® participants may claim certified credits for any AMA PRA Category 1 credit(s)™, up to a maximum of 50 credits per five-year cycle. Any additional credits are eligible as non-certified credits. College of Family Physicians of Canada (CFPC) members must log into Mainpro+® to claim this activity.

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Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

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Navigating New Frontiers in Rhythm Control in Atrial Fibrillation: Real-World Patient Encounters

Authors: Peter R. Kowey, MDFaculty and Disclosures

CME / ABIM MOC Released: 3/28/2023

Valid for credit through: 3/28/2024, 11:59 PM EST


Martin is a 66-year-old businessman who sees a cardiologist after his smartwatch alerted him an elevated heart rate. He has been having symptoms of dyspnea and fatigue and feeling overall unwell for the last few days. with a history of hypertension, hypercholesterolemia, and heart failure. He is taking enalapril 20 mg daily, dapagliflozin 10mg daily, atorvastatin 20 mg daily, carvedilol 25 mg daily. His medical records show a resting heart rate 135 bpm, HbA1c 6.8%, eGFR 60 mL/min/1.73m2, blood pressure 130/80 mmHg, total cholesterol 210 mg/dL, and left ventricular ejection fraction (LVEF) (previous visit) 60%.

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