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CME / ABIM MOC

BTK Inhibitors for CLL and MCL: What the Latest Data Mean for Our Patients

  • Authors: Stephan Stilgenbauer, MD; Toby A. Eyre, MD, MBChB, DipMedEd, MRCP, FRCPath; Jennifer A. Woyach, MD
  • CME / ABIM MOC Released: 3/21/2023
  • Valid for credit through: 3/21/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 0.75 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.75 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for hematology/oncology specialists and pathologists.

The goal of this activity is for learners to be better able to understand the latest data related to the use of Bruton tyrosine kinase (BTK) inhibitor (BTKi) therapy in patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) and mantle cell lymphoma (MCL), and the implications for current and future clinical practice.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Latest clinical trial data on BTK inhibitors for R/R CLL/SLL
    • Latest clinical trial data on BTK inhibitors for R/R MCL
  • Demonstrate greater confidence in my ability to
    • Describe the most recent data on BTK inhibitors for patients with B-cell malignancies


Disclosures

Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.

Disclosures for additional planners can be found here.


Moderator

  • Stephan Stilgenbauer, MD

    Professor of Medicine and Medical Director
    Comprehensive Cancer Center Ulm (CCCU)
    Head, Early Clinical Trials Unit (ECTU)
    Head, Division of CLL Dept. of Internal Medicine III
    Comprehensive Cancer Center Ulm (CCCU)
    Ulm, Germany

    Disclosures

    Stephan Stilgenbauer, MD, has the following relevant financial relationships:
    Consultant or advisor for: AbbVie Inc.; Acerta Pharma; Amgen Inc.; AstraZeneca; BeiGene (Beijing) Co., Ltd; Bristol Myers Squibb Company; Celgene Corporation; F. Hoffmann-La Roche Ltd; Gilead Sciences, Inc.; GlaxoSmithKline; Infinity Pharmaceuticals, Inc.; Janssen Pharmaceuticals; Novartis; Sunesis Pharmaceuticals, Inc.; Verastem, Inc.
    Speaker or member of speakers bureau for: AbbVie Inc.; Acerta Pharma; Amgen Inc.; AstraZeneca; BeiGene (Beijing) Co., Ltd; Bristol Myers Squibb Company; Celgene Corporation; F. Hoffmann-La Roche Ltd; Gilead Sciences, Inc.; GlaxoSmithKline; Infinity Pharmaceuticals, Inc.; Janssen Pharmaceuticals; Novartis; Sunesis Pharmaceuticals, Inc.; Verastem, Inc.
    Research funding from: AbbVie Inc.; Acerta Pharma; Amgen Inc.; AstraZeneca; BeiGene (Beijing) Co., Ltd; Bristol Myers Squibb Company; Celgene Corporation; F. Hoffmann-La Roche Ltd; Gilead Sciences, Inc.; GlaxoSmithKline; Infinity Pharmaceuticals, Inc.; Janssen Pharmaceuticals; Novartis; Sunesis Pharmaceuticals, Inc.; Verastem, Inc.
    Contracted researcher for: AbbVie Inc.; Acerta Pharma; Amgen Inc.; AstraZeneca; BeiGene (Beijing) Co., Ltd; Bristol Myers Squibb Company; Celgene Corporation; F. Hoffmann-La Roche Ltd; Gilead Sciences, Inc.; GlaxoSmithKline; Infinity Pharmaceuticals, Inc.; Janssen Pharmaceuticals; Novartis; Sunesis Pharmaceuticals, Inc.; Verastem, Inc.

Faculty

  • Toby A. Eyre, MD, MBChB, DipMedEd, MRCP, FRCPath

    Consultant Hematologist
    Oxford Cancer and Haematology Centre
    Churchill Hospital
    Oxford University Hospitals NHS Foundation Trust
    Oxford, United Kingdom

    Disclosures

    Toby A. Eyre, MD, MBChB, DipMedEd, MRCP, FRCPath, has the following relevant financial relationships:
    Consultant or advisor for: AbbVie Inc.; Autolus; AstraZeneca; BeiGene (Beijing) Co., Ltd; Gilead Sciences, Inc.; Incyte Corporation; Janssen Pharmaceuticals; Kite Pharma, Inc.; Loxo Oncology; Roche; Secura Bio
    Speaker or member of speakers bureau for: AbbVie Inc.; AstraZeneca; Gilead Sciences, Inc.; Incyte Corporation; Janssen Pharmaceuticals; Kite Pharma, Inc.; Loxo Oncology; Roche; Takeda
    Research funding from: AstraZeneca; BeiGene (Beijing) Co., Ltd
    Contracted researcher for: Loxo Oncology

  • Jennifer A. Woyach, MD

    Professor of Medicine
    Division of Hematology
    The Ohio State University Comprehensive Cancer Center
    Columbus, Ohio, United States

    Disclosures

    Jennifer A. Woyach, MD, has the following relevant financial relationships:
    Consultant or advisor for: AbbVie Inc.; ArQule; AstraZeneca; BeiGene (Beijing) Co., Ltd; Genentech, Inc.; Janssen Pharmaceuticals; Loxo Oncology; Newave; Pharmacyclics, Inc.
    Research funding from: AbbVie Inc.; Karyopharm Therapeutics; Loxo Oncology; MorphoSys; Schrödinger, Inc.; Verastem, Inc.

Editors

  • Sanneke Koekkoek

    Medical Education Director, WebMD Global, LLC

    Disclosures

    Sanneke Koekkoek has no relevant financial relationships.

  • Chii Shyang Fong, PhD

    Scientific Content Manager, WebMD Global, LLC

    Disclosures

    Chii Shyang Fong, PhD, has no relevant financial relationships.

Compliance Reviewer

  • Leigh Schmidt, MSN, RN, CNE, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Leigh Schmidt, MSN, RN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.


Accreditation Statements

Developed through a collaboration between Medscape Oncology and The Leukemia & Lymphoma Society (LLS).

Medscape

Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.75 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / ABIM MOC

BTK Inhibitors for CLL and MCL: What the Latest Data Mean for Our Patients

Authors: Stephan Stilgenbauer, MD; Toby A. Eyre, MD, MBChB, DipMedEd, MRCP, FRCPath; Jennifer A. Woyach, MDFaculty and Disclosures

CME / ABIM MOC Released: 3/21/2023

Valid for credit through: 3/21/2024, 11:59 PM EST

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