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Tackling the Barriers to the Accurate Diagnosis and Optimal Management of Bipolar Depression

  • Authors: James Sloan Manning, MD; Sara Jones, PhD, APRN, PMHNP-BC, FAAN, FAANP
  • CME / CE Released: 3/2/2023
  • Valid for credit through: 3/2/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 0.50 AMA PRA Category 1 Credit(s)™

    Nurses - 0.50 ANCC Contact Hour(s) (0 contact hours are in the area of pharmacology)

    You Are Eligible For

    • Letter of Completion

Target Audience and Goal Statement

Psychiatry/mental health and primary care clinicians who manage patients with bipolar depression.

Seventy percent of patients with bipolar depression are misdiagnosed at their initial visit. This worsens their prognosis, results in mistreatment, decreased quality of life, and increased suicide risk. The symptoms of a bipolar depressive episode are identical to unipolar depression. Learn from James S. Manning, MD, and Sara Jones, PhD, APRN, as they discuss tools and strategies to improve diagnostic accuracy and optimize treatment. Additionally, the panel is joined by a surprise guest and further informed by a patient experience survey highlighting what matters most to patients.

Upon completion of this activity, participants should be better able to:

  • Utilize established screening tools and diagnostic criteria to identify patients with bipolar depression
  • Individualize treatment for episodes of bipolar depression


Disclosure of Financial Relationships

RMEI Medical Education, LLC (RMEI) requires instructors, planners, managers, and others in control of educational content to disclose all their financial relationships with ineligible companies over the previous 24 months. All identified financial relationships are thoroughly vetted and mitigated according to RMEI policy.

Faculty Affiliation and Disclosures

  • James Sloan Manning, MD

    Family Physician
    High Point Family Medicine
    High Point, North Carolina


    James Sloan Manning, MD, has the following relevant financial relationships:   
    Consultant or advisor for: Alfasigma USA, Inc.; Alkermes, Inc.; Intra-Cellular Therapies, Inc.

  • Sara Jones, PhD, APRN, PMHNP-BC, FAAN, FAANP

    Associate Professor
    College of Nursing and Health Professions
    McNeese State University
    Lake Charles, Louisiana
    Journey Wellness Clinic, PLLC
    North Little Rock, Arkansas


    Sara Jones, PhD, APRN, PMHNP-BC, FAAN, FAANP, has no relevant financial relationships. 

The patient participating in this activity has no relevant financial relationship(s).

All of the relevant financial relationships listed for these individuals have been mitigated according to RMEI policies. 

Planners and Managers 
RMEI Medical Education, LLC planners and managers have no relevant financial relationship(s).

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.  


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.  

Accreditation Statements

Interprofessional Continuing Education

In support of improving patient care, RMEI Medical Education, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • RMEI Medical Education, LLC designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

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    For Nurses

  • The maximum number of hours awarded for this Continuing Nursing Education activity is 0.5 contact hour(s). 

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

Instructions for Participation and Credit

In order to receive credit, participants must review the activity content and successfully complete both the post-test and evaluation. A statement of credit will be available to print immediately. You must score 75% or higher on the post-test to receive credit for this activity. If you have questions about this activity, please contact RMEI at [email protected].

Users must:

  • Read the learning objectives and faculty disclosures
  • Participate in the activity
  • Complete the activity evaluation and attest to credit

There is no fee to participate.


Tackling the Barriers to the Accurate Diagnosis and Optimal Management of Bipolar Depression

Authors: James Sloan Manning, MD; Sara Jones, PhD, APRN, PMHNP-BC, FAAN, FAANPFaculty and Disclosures

CME / CE Released: 3/2/2023

Valid for credit through: 3/2/2024, 11:59 PM EST


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