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CME

Cholestasis in Paediatric Practice: Advances in Diagnosing and Managing Alagille Syndrome

  • Authors: Richard Thompson, BA, BM BCh, Medicine; Lorenzo D'Antiga, MD, FEBT; Binita M. Kamath, MBBChir, MRCP, MTR
  • CME Released: 3/1/2023
  • Valid for credit through: 3/1/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 0.50 AMA PRA Category 1 Credit(s)™

    You Are Eligible For

    • Letter of Completion

Target Audience and Goal Statement

This activity is intended for pediatric hepatologists, gastroenterologists, pediatricians, and other physicians involved in the diagnosis and management of cholestatic liver diseases.

The goal of this activity is for learners to be better able to differentially diagnose Alagille syndrome and select an appropriate treatment strategy.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Heterogeneous clinical characteristics of Alagille syndrome
    • Differential diagnosis of Alagille syndrome
  • Have greater competence related to
    • Managing patients with Alagille syndrome based on the latest evidence


Disclosures

Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.

Disclosures for additional planners can be found here.


Moderator

  • Richard Thompson, BA, BM BCh, Medicine

    Professor of Molecular Hepatology
    King's College London, Institute of Liver Studies
    King's College Hospital
    London, United Kingdom

    Disclosures

    Richard Thompson, BA, BM BCh, Medicine, has the following relevant financial relationships:
    Consultant or advisor for: Albireo; Generation Bio; Mirum Pharmaceuticals; Rectify
    Speaker or member of speakers bureau for: Albireo; Mirum Pharmaceuticals
    Research funding from: Albireo; Mirum Pharmaceuticals
    Stock options from: Generation Bio
    Owns stock (privately owned) in: Rectify

Faculty

  • Lorenzo D'Antiga, MD, FEBT

    Director
    Child Health Centre for Paediatric Hepatology, Gastroenterology and Transplantation
    Hospital Papa Giovanni XXIII
    Bergamo, Italy

    Disclosures

    Lorenzo D'Antiga, MD, FEBT, has the following relevant financial relationships:
    Consultant or advisor for: Albireo; Alexion Pharmaceuticals, Inc.; AstraZeneca Pharmaceuticals LP; Genespire; Mirum Pharmaceuticals; Selecta; Spark; Tome; Vivet
    Speaker or member of speakers bureau for: Takeda Pharmaceuticals North America, Inc.

  • Binita M. Kamath, MBBChir, MRCP, MTR

    Division Head (interim)
    Fellowship Program Director
    Gastroenterology, Hepatology and Nutrition
    The Hospital for Sick Children
    Toronto, Ontario, Canada

    Disclosures

    Binita M. Kamath, MBBChir, MRCP, MTR, has the following relevant financial relationships:
    Consultant or advisor for: Albireo; Audentes; Mirum Pharmaceuticals
    Research funding from: Albireo; Mirum Pharmaceuticals

Editor

  • Gillian Griffith, BA (Mod), MA

    Medical Education Director, WebMD Global, LLC

    Disclosures

    Gillian Griffith, BA (Mod), MA, has no relevant financial relationships.

Compliance Reviewer

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Stephanie Corder, ND, RN, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

The patients featured in this activity have no relevant financial relationships.​


Accreditation Statements

Medscape

Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME

Cholestasis in Paediatric Practice: Advances in Diagnosing and Managing Alagille Syndrome

Authors: Richard Thompson, BA, BM BCh, Medicine; Lorenzo D'Antiga, MD, FEBT; Binita M. Kamath, MBBChir, MRCP, MTRFaculty and Disclosures

CME Released: 3/1/2023

Valid for credit through: 3/1/2024, 11:59 PM EST

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