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Best Practices in the Care of Adult Patients With Spinal Muscular Atrophy

  • Authors: Perry Shieh, MD, PhD; Sally Dunaway Young, PT, DPT; Ikjae Lee, MD; Tina Duong, PT, PhD
  • CME / ABIM MOC / CE Released: 1/20/2023
  • Valid for credit through: 1/20/2024, 11:59 PM EST
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  • Credits Available

    Physicians - maximum of 0.50 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.50 ABIM MOC points

    Nurses - 0.50 ANCC Contact Hour(s) (0.25 contact hours are in the area of pharmacology)

    IPCE - 0.25 Interprofessional Continuing Education (IPCE) credit 

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for neurologists, orthopedists, orthopedic surgeons, physical therapists, nurses/nurse practitioners and primary care physicians.

The goal of this activity is for learners to be better able to identify the needs specific to adult patients with SMA, the role of key team members involved in the care of adult patients with SMA, and the impact of current therapeutics on adult patients with SMA.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Burden of disease for adult patients with SMA
    • Clinical data on the use of approved pharmacotherapies for the management of SMA in adult patients
    • Differential responsibilities relating to the care of adult patients with SMA between neurologists and advanced practice providers


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.

Disclosures for additional planners can be found here.


  • Perry Shieh, MD, PhD

    Professor of Neurology and Pediatrics
    University of California Los Angeles
    Los Angeles, California


    Perry Shieh, MD, PhD, has the following relevant financial relationships:
    Consultant or advisor for: Alexion; Biogen; Gene Therapies; Genentech; Novartis; Pfizer; Sarepta Therapeutics
    Speaker or member of speakers bureau for: Alexion; Argenx; Biogen; Catalyst; CSL Behring; Grifols; Genentech
    Research funding from: AMO Pharma; Astellas Gene Therapies; Biogen; Catalyst Pharmaceuticals; Fulcrum Therapeutics; Novartis Gene Therapies; Pfizer; PTC Therapeutics; ReveraGen BioPharma; Sarepta Therapeutics; Solid Biosciences

  • Sally Dunaway Young, PT, DPT

    Research Physical Therapist
    Clinical Research Manager
    Stanford University School of Medicine
    Palo Alto, California


    Sally Dunaway Young, PT, DPT, has the following relevant financial relationships:
    Consultant or advisor for: Biogen Idec; Roche; Scholar Rock
    Research funding from: Biogen; Ionis Pharmaceuticals

  • Ikjae Lee, MD

    Assistant Professor of Neurology
    Columbia University Irving Medical Center
    New York, New York


    Ikjae Lee, MD, has the following relevant financial relationships:
    Consultant or advisor for: Alexion

  • Tina Duong, PT, PhD

    Physical Therapist
    Director Clinical Outcomes Research & Development
    Division of Neuromuscular Medicine
    Stanford University School of Medicine
    Stanford, California


    Tina Duong, PT, PhD, has no relevant financial relationships.


  • Katherine Carpenter, PhD

    Medical Education Director, WebMD Global, LLC


    Katherine Carpenter, PhD, has the following relevant financial relationship:
    Advisor or consultant for: Eisai (former), GW Pharmaceuticals (former)

  • Yoji Yamaguchi, MA, ELS

    Scientific Content Manager, WebMD Global, LLC


    Yoji Yamaguchi, MA, ELS, has no relevant financial relationships.

  • Pakinam Aboulsaoud, ​PharmD​

    Senior Medical Education Director​, Medscape, LLC


    ​​Pakinam Aboulsaoud​, ​PharmD​, has no relevant financial relationships. 

  • Megan Breuer, PhD

    Medical Writer, Medscape, LLC


    Megan Breuer, PhD, has the following relevant financial relationships:  
    Consultant/advisor for: Paratek Pharmaceuticals, Inc. (former) 
    Owns stock (publicly traded) in: Bristol Myers Squibb Company; Johnson and Johnson; Paratek Pharmaceuticals, Inc; Vertex Pharmaceuticals, Inc. 

Compliance Reviewer/Nurse Planner

  • Lisa Simani, APRN, MS, ACNP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Lisa Simani, APRN, MS, ACNP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.

Accreditation Statements

Developed through a partnership between Medscape and Cure SMA.


Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


This activity was planned by and for the healthcare team, and learners will receive 0.25 Interprofessional Continuing Education (IPCE) credit for learning and change.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50  AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to ​0.50​ MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity. 

    Contact This Provider

    For Nurses

  • Awarded ​0.50​ contact hour(s) of nursing continuing professional development for RNs and APNs; ​0.25​ contact hours are in the area of pharmacology. 

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


Best Practices in the Care of Adult Patients With Spinal Muscular Atrophy

Authors: Perry Shieh, MD, PhD; Sally Dunaway Young, PT, DPT; Ikjae Lee, MD; Tina Duong, PT, PhDFaculty and Disclosures

CME / ABIM MOC / CE Released: 1/20/2023

Valid for credit through: 1/20/2024, 11:59 PM EST


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