You are leaving Medscape Education
Cancel Continue
Log in to save activities Your saved activities will show here so that you can easily access them whenever you're ready. Log in here CME & Education Log in to keep track of your credits.


Ending the Diagnostic Odyssey: Genetic Diagnosis in Children Affected by Epilepsy

  • Authors: Neil A. Hanchard, MD, PhD; Ingo Helbig, MD; Lacey Smith, MS, CGC; J. Michael Graglia, MBA, MA
  • CME / ABIM MOC / CE Released: 12/2/2022
  • Valid for credit through: 12/2/2023, 11:59 PM EST
Start Activity

Target Audience and Goal Statement

This activity is intended for neurologists, pediatricians, primary care physicians, medical geneticists, psychiatrists, psychologists, nurses, and advanced practice providers.

The goal of this activity is for learners to be better able to utilize and interpret gene testing as part of the diagnostic workup of pediatric patients with seizures.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Genetics of epilepsy
    • Unmet needs in the management of epilepsy
    • Utility of genetic testing in the management of epilepsy
  • Have greater competence related to
    • Selection of genetic tests in epilepsy
  • Demonstrate greater confidence in their ability to
    • Make appropriate management decisions based on the results of genetic testing


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


  • Neil A. Hanchard, MD, PhD

    Adjunct Associate Professor
    Department of Molecular and Human Genetics
    Baylor College of Medicine
    Houston, Texas
    Senior Investigator
    Center for Precision Health Research
    National Human Genome Research Institute
    Bethesda, Maryland


    The views expressed by Dr Hanchard are his own and do not necessarily represent the views of the National Institutes of Health or the US Government.
    Neil A. Hanchard, MD, PhD, has no relevant financial relationships.


  • Ingo Helbig, MD

    Assistant Professor of Neurology
    Perelman School of Medicine
    University of Pennsylvania
    Director of Genomic Science
    Epilepsy NeuroGenetics Initiative (ENGIN)
    Philadelphia, Pennsylvania


    Ingo Helbig, MD, has the following relevant financial relationships:
    Consultant or advisor for: Biogen
    Research funding from: Ambit, Inc.; Encoded Therapeutics
    Patent beneficiary of: US Patent Application No 62/843,859 (micro-RNA site-blocking oligonucleotides to treat epileptic encephalopathies and neurodevelopmental disorder)

  • Lacey Smith, MS, CGC

    Genetic Counseling Program Manager
    Epilepsy Genomics
    Department of Neurology
    Boston Children's Hospital
    Boston, Massachusetts


    Lacey Smith, MS, CGC, has no relevant financial relationships.

Patient Advocate

  • J. Michael Graglia, MBA, MA

    Co-Founder and Managing Director
    SynGAP Research Fund, 501(c)(3)
    Palo Alto, California


    J. Michael Graglia, MBA, MA, has no relevant financial relationships.


  • Frances McFarland, PhD, MA

    Medical Education Director, Medscape, LLC


    Frances McFarland, PhD, MA, has no relevant financial relationships.

Compliance Reviewer/Nurse Planner

  • Lisa Simani, APRN, MS, ACNP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Lisa Simani, APRN, MS, ACNP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.

Accreditation Statements


Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.25 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    Contact This Provider

    For Nurses

  • Awarded ​1.25​ contact hour(s) of nursing continuing professional development for RNs and APNs; ​0.00​ contact hours are in the area of pharmacology.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


Ending the Diagnostic Odyssey: Genetic Diagnosis in Children Affected by Epilepsy

Authors: Neil A. Hanchard, MD, PhD; Ingo Helbig, MD; Lacey Smith, MS, CGC; J. Michael Graglia, MBA, MAFaculty and Disclosures

CME / ABIM MOC / CE Released: 12/2/2022

Valid for credit through: 12/2/2023, 11:59 PM EST


Learning Feedback Questions

Please answer these questions to complement your learning experience.

  • Print