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Understanding the Genomics of Ovarian Cancer: PARP Inhibitors Edition

  • Authors: Bradley J. Monk, MD, FACS, FACOG
  • CME / ABIM MOC Released: 11/29/2022
  • Valid for credit through: 11/29/2023
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  • Credits Available

    Physicians - maximum of 0.50 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.50 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for oncologists, pathologists, obstetrician/gynecologists (ob/gyns), and other clinicians involved in care of patients with ovarian cancer.

The goal of this activity is for learners to be better able to understand the role of genetic testing in ovarian cancer and incorporate it in patient care.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Role of genetics in treatment selection for patients with ovarian cancer
    • Categorization of PARP inhibitor therapy options by the appropriate genetic mutation and stage of care
  • Have greater competence related to
    • Selection of appropriate PARP inhibitor therapies based on patient-specific genetics and most up-to-date indications
  • Demonstrate greater confidence in their ability to
    • Refer patients to genetic counselors for optimal management of ovarian cancer


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


  • Bradley J. Monk, MD, FACS, FACOG

    Division of Gynecologic Oncology  
    University of Arizona College of Medicine  
    Director, Principal Investigator, Community Research Development  
    HonorHealth Research Institute  
    Phoenix, Arizona


    Bradley J. Monk, MD, FACS, FACOG, has the following relevant financial relationships:
    ​Consultant or advisor for: Acrivon; Adaptimune; Agenus; Akeso Bio; Amgen; Aravive; AstraZeneca; Bayer; Clovis; Easai; Elevar; EMD Merck; Genmab/Seagen; Gradalis; Heng Rui; ImmunoGen; Iovance; Karyopharm; Laekna; Macrogenics; Merck; Mersana; Myriad; Novocure; OncoC4; Panavance; Pfizer; Pieris; Puma; Regeneron; Roche/Genentech; Sorrento; TESARO/GlaxoSmithKline; US Oncology Research; VBL; Verastem; Zentalis 
    Speaker or member of speakers bureau for: AstraZeneca; Clovis; Easai; Merck; Myriad; Roche/Genentech; TESARO/GlaxoSmithKline
    Other: Investigator: Gradalis Inc.; US Oncology Research; Honorarium: Novartis​


  • Amy Furedy, RN, OCN

    Medical Education Director, Medscape, LLC


    Amy Furedy, RN, OCN, has no relevant financial relationships.

Compliance Reviewer

  • Leigh Schmidt, MSN, RN, CNE, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Leigh Schmidt, MSN, RN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


Understanding the Genomics of Ovarian Cancer: PARP Inhibitors Edition

Authors: Bradley J. Monk, MD, FACS, FACOGFaculty and Disclosures

CME / ABIM MOC Released: 11/29/2022

Valid for credit through: 11/29/2023


Educational Impact Challenge

The goal of this activity is for learners to be better able to understand the role of genetic testing in ovarian cancer and incorporate it in patient care.

Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.

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