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CME / ABIM MOC

High-Efficacy Therapies Early in Multiple Sclerosis: Which B-Cell Therapies and Why?

  • Authors: Jiwon Oh, MD, PhD, FRCPC; Michael Barnett, MBBS, FRACP, PhD; Reza Vosoughi, MD, FRCPC; Fraser Clift, MD, FRCPC
  • CME / ABIM MOC Released: 11/23/2022
  • Valid for credit through: 11/23/2023
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  • Credits Available

    Physicians - maximum of 0.50 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.50 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for Canadian neurologists, primary care physicians, and healthcare professionals with a practice in multiple sclerosis (MS).

The goal of this activity is for learners to be better able to use high-efficacy therapies early in MS and to be able to differentiate among B-cell therapies.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding
    • Benefits and limitations of using high-efficacy therapies early in MS
    • Efficacy and safety differences among B-cell-targeted therapies in MS
    • Efficacy and safety differences among B-cell-targeted therapies in MS
  • Have greater competence related to
    • Selection of B-cell-targeted therapies according to patient profile in MS


Disclosures

Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


Moderator

  • Jiwon Oh, MD, PhD, FRCPC

    Associate Professor of Neurology
    Medical Director, BARLO MS Program
    St. Michael’s Hospital
    University of Toronto
    Toronto, Ontario, Canada

    Disclosures

    Jiwon Oh, MD, PhD, FRCPC, has the following relevant financial relationships: 
    Consultant or advisor for: Biogen Idec; Bristol Myers Squibb Company; EMD Serono; Novartis; Roche; Sanofi-Genzyme 
    Speaker or member of speakers bureau for: Biogen Idec; EMD Serono; Roche; Sanofi-Genzyme
    Research funding from: Biogen Idec; EMD Serono; Roche 

Faculty

  • Michael Barnett, MBBS, FRACP, PhD

    Professor of Neurology
    Director, RPAH MS Clinical Trials Unit
    Brain and Mind Centre
    Co-Director, MS Research Australia Brain Bank
    Royal Prince Alfred Hospital
    Sydney, New South Wales, Australia

    Disclosures

    Michael Barnett, MBBS, FRACP, PhD, has no relevant financial relationships.

  • Reza Vosoughi, MD, FRCPC

    Associate Professor of Neurology
    St. Michael’s Hospital
    Toronto, Ontario, Canada

    Disclosures

    Reza Vosoughi, MD, FRCPC, has the following relevant financial relationships: 
    Consultant or advisor for: Biogen; Bristol Myers Squibb Company; EMD Serono; Genzyme; Novartis; Roche
    Research funding from: Atara Biotherapeutics; Novartis; Roche
    Contracted researcher for: Atara Biotherapeutics; Novartis; Roche

  • Fraser Clift, MD, FRCPC

    Associate Professor of Neurology
    Memorial University of Newfoundland
    Newfoundland and Labrador, Canada

    Disclosures

    Fraser Clift, MD, FRCPC, has the following relevant financial relationships: 
    Consultant or advisor for: Alexion; Biogen; Bristol Myers Squibb Company; EMD Serono; Novartis; Roche; Sanofi

Editor

  • Maya Khalaf, MSc

    Associate Medical Education Director, Medscape, LLC

    Disclosures

    Maya Khalaf, MSc, has no relevant financial relationships.

Compliance Reviewer

  • Yaisanet Oyola, MD

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Yaisanet Oyola, MD, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.


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    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

    College of Family Physicians of Canada Mainpro+® participants may claim certified credits for any AMA PRA Category 1 credit(s)™, up to a maximum of 50 credits per five-year cycle. Any additional credits are eligible as non-certified credits. College of Family Physicians of Canada (CFPC) members must log into Mainpro+® to claim this activity

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / ABIM MOC

High-Efficacy Therapies Early in Multiple Sclerosis: Which B-Cell Therapies and Why?

Authors: Jiwon Oh, MD, PhD, FRCPC; Michael Barnett, MBBS, FRACP, PhD; Reza Vosoughi, MD, FRCPC; Fraser Clift, MD, FRCPCFaculty and Disclosures

CME / ABIM MOC Released: 11/23/2022

Valid for credit through: 11/23/2023

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