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CME / ABIM MOC / CE

Evaluating Complement Pathways for Paroxysmal Nocturnal Hemoglobinuria: Interprofessional Perspectives on Current and Emerging Approaches

  • Authors: Srikanth Nagalla, MD, MS; Catherine M. Broome, MD; Louise Arnold, RGN, BSc
  • CME / ABIM MOC / CE Released: 11/22/2022
  • Valid for credit through: 11/22/2023
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  • Credits Available

    Physicians - maximum of 1.00 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 1.00 ABIM MOC points

    Nurses - 1.00 ANCC Contact Hour(s) (0.5 contact hours are in the area of pharmacology)

    Pharmacists - 1.00 Knowledge-based ACPE (0.100 CEUs)

    IPCE: 1.00 Interprofessional Continuing Education (IPCE) credit

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for hematology/oncology specialists (including bone marrow failure [BMF] experts and fellows), physician assistants (PAs), nurses, and pharmacists.

The goal of this activity is for learners to be better able to understand the complement pathway within PNH and practical strategies for managing these patients as part of the interprofessional team.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Role of the therapies targeting the complement pathway for treating patients with PNH
    • Clinical trial data evaluating therapies used for the management of patients with PNH
  • Have greater competence related to
    • Managing potential adverse events associated with PNH therapies
  • Demonstrate greater confidence in their ability to
    • Coordinate with the interprofessional team to ensure optimal outcomes for patients with PNH


Disclosures

Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


Faculty

  • Srikanth Nagalla, MD, MS

    Chief of Benign Hematology
    Miami Cancer Institute
    Miami, Florida, United States

    Disclosures

    Srikanth Nagalla, MD, MS, has the following relevant financial relationships:
    Consultant or advisor for: Alexion; Alnylam; Apellis; Pharmacosmos; Rigel; Sanofi; SOBI
    Speaker or member of speakers bureau for: RIGEL; Sanofi

  • Catherine M. Broome, MD

    Associate Professor
    Department of Medicine
    MedStar Georgetown University Hospital
    Lombardi Comprehensive Cancer Center
    Columbia, Maryland, United States

    Disclosures

    Catherine M. Broome, MD, has the following relevant financial relationships:
    Consultant or advisor for: Alexion; Argenx; Sanofi; Star Therapeutics
    Speaker or member of speakers bureau for: Alexion; Sanofi
    Research funding from: Alexion; Argenx; Incyte; Rigel; Sanofi

  • Louise Arnold, RGN, BSc

    Trainee Advanced Clinical Practitioner (Nurse)
    Department of Haematology
    St James' Institute of Oncology
    Leeds, United Kingdom

    Disclosures

    Louise Arnold, RGN, BSc, has the following relevant financial relationships:
    Consultant or advisor for: Alexion UK; SOBI in UK
    Speaker or member of speakers bureau for: Alexion; SOBI

Editors

  • Deborah Middleton, MS

    Senior Medical Education Director, WebMD Global, LLC 

    Disclosures

    Deborah Middleton, MS, has no relevant financial relationships.

  • Yoji Yamaguchi, MA, ELS

    Scientific Content Manager, WebMD Global, LLC 

    Disclosures

    Yoji Yamaguchi, MA, ELS, has no relevant financial relationships.

Compliance Reviewer/Nurse Planner

  • Leigh Schmidt, MSN, RN, CNE, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Leigh Schmidt, MSN, RN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.


Accreditation Statements



In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

This activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    Contact This Provider

    For Nurses

  • Awarded 1.0 contact hour(s) of nursing continuing professional development for RNs and APNs; 0.50 contact hours are in the area of pharmacology.

    Contact This Provider

    For Pharmacists

  • Medscape designates this continuing education activity for 1.0 contact hour(s) (0.100 CEUs) (Universal Activity Number: JA0007105-0000-22-380-H01-P).

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / ABIM MOC / CE

Evaluating Complement Pathways for Paroxysmal Nocturnal Hemoglobinuria: Interprofessional Perspectives on Current and Emerging Approaches

Authors: Srikanth Nagalla, MD, MS; Catherine M. Broome, MD; Louise Arnold, RGN, BScFaculty and Disclosures

CME / ABIM MOC / CE Released: 11/22/2022

Valid for credit through: 11/22/2023

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Contents of This CME Activity

All sections of this activity are required for credit.

Overview of the Complement Pathway Within PNH

Dr Nagalla reviews the role of the complement pathway in PNH
Srikanth Nagalla, MD, MS

Diving Into the Safety and Efficacy Profiles of Current and Emerging Strategies

Are you up to date on current and emerging treatment strategies for PNH?
Catherine M. Broome, MD

Practical Considerations for Managing Patients With PNH

What are the practical considerations involved in the long-term care of patients with PNH?
Louise Arnold, RGN, BSc
 

Educational Impact Challenge

The goal of this activity is for learners to be better able to understand the complement pathway within PNH and practical strategies for managing these patients as part of the interprofessional team.

Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.