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CME / ABIM MOC / CE

Managing Off Symptoms in Patients With Parkinson Disease: Recent Data Update

  • Authors: Daniel E. Kremens, JD, MD, FAAN; Stuart Isaacson, MD; Michael Okun, MD
  • CME / ABIM MOC / CE Released: 11/14/2022
  • Valid for credit through: 11/14/2023
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  • Credits Available

    Physicians - maximum of 0.50 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.50 ABIM MOC points

    Nurses - 0.50 ANCC Contact Hour(s) (0.25 contact hours are in the area of pharmacology)

    IPCE - 0.5 Interprofessional Continuing Education (IPCE) credit

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for neurologists, orthopedists/orthosurgeons, primary care providers, nurses, nurse practitioners, physician assistants, and other healthcare professionals managing PD.

The goal of this activity is for learners to be better able to manage wearing-off (off) symptoms in patients with PD.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding
    • Clinical data pertaining to the identification of off symptoms in patients with PD
    • Clinical data for established pharmacotherapies for the management of off symptoms in PD
    • Clinical data for emerging pharmacotherapies for the management of off symptoms in PD
  • Have greater confidence in the
    • Management of off symptoms of PD within an interprofessional team


Disclosures

Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


Faculty

  • Daniel E. Kremens, JD, MD, FAAN

    Associate Professor of Neurology
    Co-Director
    Movement Disorders Program
    Vice Chair for Education Department of Neurology
    Thomas Jefferson University Hospitals
    Philadelphia, Pennsylvania

    Disclosures

    Daniel E. Kremens, JD, MD, FAAN, has the following relevant financial relationships:
    Consultant or advisor for: AbbVie, Inc.; ACADIA Pharmaceuticals Inc.; Acorda Therapeutics; Adamas Pharmaceuticals, Inc.; Allergan; Amneal; Avion; Brittania Pharmaceuticals; Kyowa Kirin Pharmaceutical Development, Inc.; Merz Pharmaceuticals; Neurocrine Biosciences, Inc.; Supernus Pharmaceuticals, Inc.; Sunovion Pharmaceuticals Inc.; Teva Pharmaceuticals USA; US WorldMeds
    Speaker or member of speakers bureau for: ACADIA Pharmaceuticals Inc.; Acorda Therapeutics; Adamas Pharmaceuticals, Inc.; Amneal, Kyowa Kirin Pharmaceutical Development, Inc.; Neurocrine Biosciences, Inc.; Sunovion Pharmaceuticals Inc.; Supernus Pharmaceuticals, Inc.; Teva Pharmaceuticals USA; US WorldMeds
    Research funding from: Revance Therapeutics, Inc.; Voyager Therapeutics

  • Stuart Isaacson, MD

    Director
    Parkinson Disease and Movement Disorders Center of Boca Raton
    Clinical Associate Professor of Neurology
    Florida International University
    Herbert Wertheim College of Medicine
    Miami, Florida

    Disclosures

    Stuart Isaacson, MD, has the following relevant financial relationships:
    Consultant or advisor for: AbbVie, Inc.; ACADIA Pharmaceuticals Inc.; Acorda Therapeutics; Adamas Pharmaceuticals, Inc.; Addex Therapeutics; Affiris; Alexz; Allergan; Amneal; Britanni Pharmaceuticals; Cala Health, Inc.; Cerecor, Inc.; Cerevel; Enterin Inc.; GE Healthcare; Global Kinetics Corporation Ltd.; IMPAX Laboratories, Inc.; Impel NeuroPharma, Inc.; Kyowa Kirin Pharmaceutical Development, Inc.; Lundbeck, Inc.; Merz Pharmaceuticals; Neurocrine Biosciences, Inc.; NeuroDerm; Pharm Two B; Revance Therapeutics, Inc.; Roche; Sage Therapeutics, Inc.; Scion Neurostim; Stoparkinson; Sunovion Pharmaceuticals Inc.; Supernus Pharmaceuticals, Inc.; Teva Pharmaceuticals USA; UCB Pharma, Inc.
    Speaker or member of speakers bureau for: AbbVie, Inc.; ACADIA Pharmaceuticals Inc.; Acorda Therapeutics; Adamas Pharmaceuticals, Inc.; Allergan, Amneal, Kyowa Kirin Pharmaceutical Development, Inc.; Neurocrine Biosciences, Inc.; Sunovion Pharmaceuticals Inc.; Supernus Pharmaceuticals, Inc.; Teva Pharmaceuticals USA
    Research funding from: AbbVie, Inc.; ACADIA Pharmaceuticals Inc.; Acorda Therapeutics; Adamas Pharmaceuticals, Inc.; Addex Therapeutics; Amneal; Aptinyx; Axial; BenevolentAI; Biogen; Biovie; Cadent; Cala Health, Inc.; Cerecor, Inc.; Cerevel; Enterin Inc.; Global Kinetics Corporation Ltd.; IMPAX Laboratories, Inc.; Intec Pharma, Ltd.; Jazz Pharmaceuticals, Inc.; Kyowa Kirin Pharmaceutical Development, Inc.; Lilly USA, LLC; Lundbeck, Inc.; Neuralys; Neurocrine Biosciences, Inc.; NeuroDerm; Novartis Pharmaceuticals; Parkinson Study Group; Pharma Two B; Praxis; Prilenia; Revance Therapeutics, Inc.; Roche; Sage Therapeutics, Inc.; Sanofi; Scion; Stoparkinson; Sunovion Pharmaceuticals Inc.; Sun Pharmaceutical Industries, Ltd.; Supernus Pharmaceuticals, Inc.; Teva Pharmaceuticals USA; Theravance, Inc.; Transposon; UCB Pharma, Inc.

  • Michael Okun, MD

    Adelaide Lackner Professor and Chair of Neurology
    Executive Director
    Norman Fixel Institute for Neurological Diseases
    University of Florida Health
    Gainesville, Florida

    Disclosures

    Michael Okun, MD, has no relevant financial relationships.

Editors

  • Nancy Ashley, MSN, APRN, ANP-BC

    Medical Education Director, Medscape, LLC

    Disclosures

    Nancy Ashley, MSN, APRN, ANP-BC, has no relevant financial relationships.

  • Christina Loguidice, BA

    Medical Education Director, Medscape, LLC

    Disclosures

    Christina Loguidice, BA, has no relevant financial relationships. 

Compliance Reviewer/Nurse Planner

  • Leigh Schmidt, MSN, RN, CNE, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Leigh Schmidt, MSN, RN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.


Accreditation Statements



In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

This activity was planned by and for the healthcare team, and learners will receive 0.5 Interprofessional Continuing Education (IPCE) credit for learning and change.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    Contact This Provider

    For Nurses

  • Awarded 0.50 contact hour(s) of continuing nursing education for RNs and APNs; 0.25 contact hours are in the area of pharmacology.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / ABIM MOC / CE

Managing Off Symptoms in Patients With Parkinson Disease: Recent Data Update

Authors: Daniel E. Kremens, JD, MD, FAAN; Stuart Isaacson, MD; Michael Okun, MDFaculty and Disclosures

CME / ABIM MOC / CE Released: 11/14/2022

Valid for credit through: 11/14/2023

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Educational Impact Challenge

The goal of this activity is for learners to be better able to manage wearing-off (off) symptoms in patients with PD.

Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.