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Keeping Up With KRAS: Solid Tumor Updates From the European Annual Meeting

  • Authors: Alexander Spira, MD, PhD, FACP
  • CME / ABIM MOC Released: 10/28/2022
  • Valid for credit through: 10/28/2023, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for oncologists, pathologists, gastroenterologists, pulmonologists, surgeons, and other healthcare professionals who care for patients with cancer.

The goal of this activity is for learners to be better able to recognize and incorporate recent data into the clinical care of patients with KRAS G12C-mutated solid tumors.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Key clinical trial data evaluating KRAS-targeted therapies for the treatment of solid tumors
  • Have greater competence related to
    • Incorporating recent KRAS data into the treatment of patients with solid tumors
  • Demonstrate greater confidence in their ability to
    • Stay abreast of evolving KRAS management strategies for patients with solid tumors


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All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


  • Alexander Spira, MD, PhD, FACP

    Clinical Research Director
    Virginia Cancer Specialists
    Chief Executive Officer
    NEXT Virginia
    Fairfax, Virginia


    Alexander Spira, MD, PhD, FACP, has the following relevant financial relationships: 
    Consultant or advisor for: Amgen; Array BioPharma; AstraZeneca/MedImmune; Blueprint Medicines; Bristol Myers Squibb; Daiichi Sankyo/AstraZeneca; Gritstone Bio; Gritstone Oncology; Incyte; Janssen Research & Development; Jazz Pharmaceuticals; Merck; Mersana; Mirati Therapeutics; Novartis; Regeneron; Takeda
    Research funding from: AbbVie; ADCT; Alkermes; Amgen; Arch Therapeutics; Astellas Pharma; Astex Pharmaceuticals; AstraZeneca; Blueprint Medicines; Boehringer Ingelheim; Bristol Myers Squibb; CytomX Therapeutics; Daiichi Sankyo; Gritstone; Ignyta; Incyte; Janssen Oncology; LAM Therapeutics; Loxo; MacroGenics; MedImmune; Mersana; Mirati Therapeutics; NewLink Genetics; Novartis; Plexxikon; Regeneron; Revolution Medicines; Roche; Rubius Therapeutics; Synthekine; Takeda; Trovagene 
    Owns stock (publicly traded) in: Eli Lilly
    Other: Honoraria from: Amgen; AstraZeneca/MedImmune; Bayer; Bristol Myers Squibb; CytomX Therapeutics; Janssen Oncology; Merck; Novartis; Takeda


  • Amy Furedy, RN, OCN

    Medical Education Director, Medscape, LLC


    Amy Furedy, RN, OCN, has no relevant financial relationships.

  • Ryan K. Blanchard

    Medical Writer, Medscape, LLC


    Ryan K. Blanchard has no relevant financial relationships.

Compliance Reviewer/Nurse Planner

  • Leigh Schmidt, MSN, RN, CNE, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Leigh Schmidt, MSN, RN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

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  • Medscape, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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Keeping Up With KRAS: Solid Tumor Updates From the European Annual Meeting

Authors: Alexander Spira, MD, PhD, FACPFaculty and Disclosures

CME / ABIM MOC Released: 10/28/2022

Valid for credit through: 10/28/2023, 11:59 PM EST


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