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Rare Pediatric Epilepsies in Adult Neurology: Sharpening Your Specter of Suspicion

  • Authors: Anup D. Patel, MD; Elizabeth A. Thiele, MD, PhD
  • CME / ABIM MOC Released: 10/17/2022
  • Valid for credit through: 10/17/2023, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for neurologists, primary care physicians, pediatricians, and other clinicians involved in the care of patients with rare neurological diseases.

The goal of this activity is for learners to be better able to identify a missed diagnosis of Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC) in the adult neurology setting, and what such a diagnosis indicates for the selection of anti-seizure medications.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Diagnostic criteria for rare pediatric-onset epilepsies
  • Have greater competence related to
    • Accurately diagnosing a rare pediatric-onset epilepsy in an adult patient
    • Selecting an appropriate medication for the management of seizures in adult patients with rare pediatric-onset epilepsies


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.

Disclosures for additional planners can be found here.


  • Anup D. Patel, MD

    Associate Professor, Clinical Pediatrics and Neurology
    The Ohio State University College of Medicine
    Section Chief, Pediatric Neurology
    Nationwide Children's Hospital
    Columbus, Ohio


    Anup D. Patel, MD, has the following relevant financial relationships:
    Consultant or advisor for: Jazz Pharmaceuticals; Neurelis
    Research funding from: Encoded; Greenwich Biosciences; Stoke Therapeutics


  • Elizabeth A. Thiele, MD, PhD

    Professor of Neurology
    Harvard Medical School
    Director, Pediatric Epilepsy Program
    Director, Carol and James Herscot Center for Tuberous Sclerosis Complex
    Massachusetts General Hospital
    Boston, Massachusetts


    Elizabeth A. Thiele, MD, PhD, has the following relevant financial relationships:
    Consultant or advisor for: Aditum; Azurity; BridgeBio; GW Pharmaceuticals; Jazz Pharmaceuticals; LivaNova; Marinus; Nobelpharma; Radius Health; Stoke Therapeutics; Zogenix
    Research funding from: GW Pharmaceuticals; Jazz Pharmaceuticals; Stoke Therapeutics; Zogenix
    Contracted researcher for: GW Pharmaceuticals; Jazz Pharmaceuticals; Zogenix


  • Walid Amara, MD

    Medical Education Director, WebMD Global, LLC


    Walid Amara, MD, has no relevant financial relationships.

Compliance Reviewer

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Stephanie Corder, ND, RN, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

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    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

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This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

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Rare Pediatric Epilepsies in Adult Neurology: Sharpening Your Specter of Suspicion

Authors: Anup D. Patel, MD; Elizabeth A. Thiele, MD, PhDFaculty and Disclosures

CME / ABIM MOC Released: 10/17/2022

Valid for credit through: 10/17/2023, 11:59 PM EST


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