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Managing Patients With Moderate to Severe Atopic Dermatitis: What's Your Approach?

  • Authors: Alan D. Irvine, MD, DSc
  • CME Released: 11/16/2022
  • Valid for credit through: 11/16/2023, 11:59 PM EST
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Target Audience and Goal Statement

This educational activity is intended for an international audience of non-US dermatologists.

The goal of this activity is for learners to better describe the burden of moderate to severe AD and how best to conduct patient assessment. In addition, learners will appreciate the mechanism of action and key clinical data for emerging biologic treatments, and the factors influencing treatment selection.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Factors influencing treatment selection in a complex treatment landscape
  • Have greater competence related to
    • Managing patients with moderate to severe AD
    • Evaluating the severity of AD
  • Demonstrate greater confidence in their ability to
    • Evaluate the severity of AD


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


  • Alan D. Irvine, MD, DSc

    Trinity College Dublin
    Dublin, Ireland


    Alan D. Irvine, MD, DSc, has the following relevant financial relationships: 
    Consultant or advisor for: AbbVie; Amgen; Arena; Benevolent AI; Eli Lilly; LEO Pharma; Novartis; Pfizer; Regeneron; Sanofi Genzyme
    Speaker or member of speakers bureau for: AbbVie; Eli Lilly; LEO Pharma; Novartis; Pfizer; Regeneron; Sanofi Genzyme


  • Stuart Crayford, MSc, LLM

    Medical Education Director, Medscape, LLC


    Stuart Crayford, MSc, LLM, has no relevant financial relationships.

  • Christina T. Loguidice, BA

    Medical Writer, Medscape, LLC


    Christina T. Loguidice, BA, has no relevant financial relationships.

Compliance Reviewer

  • Lisa Simani, APRN, MS, ACNP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Lisa Simani, APRN, MS, ACNP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements


Interprofessional Continuing Education

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    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

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There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

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  1. Read the target audience, learning objectives, and author disclosures.
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  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

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Managing Patients With Moderate to Severe Atopic Dermatitis: What's Your Approach?

Authors: Alan D. Irvine, MD, DScFaculty and Disclosures

CME Released: 11/16/2022

Valid for credit through: 11/16/2023, 11:59 PM EST


The following cases are modeled on the interactive grand rounds approach. The questions within the activity are designed to test your current knowledge. After each question, you will be able to see whether you answered correctly and read evidence-based information that supports the most appropriate answer choice. The questions are designed to challenge you; you will not be penalized for answering the questions incorrectly. At the end of the activity, there will be a short post-test assessment based on the material presented.


Ellie is a 20-year-old university student who has had atopic dermatitis (AD) since she was an infant. Her AD was considered mild in childhood, with only small areas of skin involvement and intermittent flares that usually spontaneously remitted. She has now come to your clinic to seek care as an adult. She notes that over the past year she has had more flares and that lesions have started to manifest on her face, elbow, and hands, causing her considerable distress. Ellie expresses embarrassment over her appearance and explains that she has always struggled with self-esteem. Because of her AD becoming more visible, she has started avoiding going out with her friends and says she has been emotional and stress eating, causing her to gain about 4 kg over the past 3 months. Although she is still considered a normal weight, she is concerned because obesity and type 2 diabetes mellitus run in her family. She reports feeling anxious and depressed. In addition to AD, Ellie's medical history includes asthma and a tree-nut allergy.

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