Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.

Faculty

Aditya Bardia, MD, MPH

Director
Breast Cancer Research
Massachusetts General Hospital Cancer Center
Harvard Medical School
Boston, Massachusetts

Disclosures

Aditya Bardia, MD, MPH, has the following relevant financial relationships:
Consultant or advisor for: Daiichi Pharma/AstraZeneca; Eli Lilly; Foundation Medicine; Genentech; Immunomedics/Gilead; Merck; Novartis; Pfizer, Inc.; Phillips; Radius Health; Sanofi
Research funding from: Daiichi Pharma/AstraZeneca; Eli Lilly; Genentech; Immunomedics/Gilead; Merck; Novartis; Pfizer, Inc.; Radius Health; Sanofi

Marina Garassino, MD

Professor of Medicine
Lung Cancer Program of Chicago
Department of Hematology/Oncology
University of Chicago
Chicago, Illinois

Disclosures

Marina Garassino, MD, has the following relevant financial relationships:
Consultant or advisor for: AstraZeneca; Blueprint; Boehringer Ingelheim Italia; Bristol Myers Squibb Company; Celgene; Daiichi Sankyo; Ignyta; Incyte; Inivata; Janssen; Medimmune; Merck; Merck Sharp & Dohme, Corp.; Mirati; Novartis; Ose Immuno; Pfizer; Regeneron; Roche; Sanofi; Seattle Genetics; Takeda
Research funding from: AstraZeneca; Boehringer Ingelheim Italia; Bristol Myers Squibb Company; Celgene; Foundation Medicine; GlaxoSmithKline; Ignyta; Incyte; Lilly; Medimmune; Merck Sharp & Dohme, Corp.; Novartis; Pfizer; Roche; Spectrum; Takeda; Tiziana

David O’Malley, MD

Professor, Department of Obstetrics and Gynecology
The Ohio State University College of Medicine
Director, Division of Gynecologic Oncology
The Ohio State University Comprehensive Cancer Center
Columbus, Ohio

Disclosures

David O’Malley, MD, has the following relevant financial relationships:
Consultant or advisor for: AbbVie; AdaptImmune; Agenus, Inc.; Arquer Diagnostics; Arcus Biosciences, Inc.; AstraZeneca; Atossa Therapeutics; Boston Biomedical; Cardiff Oncology; Celcuity; Clovis Oncology; Corcept Therapeutics; Duality Bio; Eisai; Elevar; Exelixis; Genentech Inc.; Genelux; GlaxoSmithKline; Hoffmann-La Roche Inc.; ImmunoGen, Inc.; Imvax; InterVenn; INXMED; IOVANCE Biotherapeutics; Janssen; Jazz Pharmaceuticals; Laekna; Leap Therapeutics, Inc.; Luzsana Biotechnology; Merck & Co.; Merck Sharp & Dohme Corp.; Mersana Therapeutics, Inc.; Myriad; Novartis; NovoCure; OncoC4, Inc.; Onconova; Regeneron Pharmaceuticals, Inc.; RepImmune; R Pharm; Roche Diagnostics; Seagen Inc.; Sorrento; Sutro Biopharma; Tarveda Therapeutics; Toray; Trillium; Umoja; Verastem, Inc.; VBL Therapeutics; Vincerx Pharma; Zencor; Zentalis
Research funding from: Abbvie; Advaxis; Agenus, Inc.; Alkermes; Aravive, Inc.; Arcus Biosciences, Inc.; AstraZeneca; Atossa Therapeutics; BeiGene USA, Inc.; Boston Biomedical; BristolMyersSquibb; Clovis Oncology; Deciphera Pharma; Eisai; EMD Serono, Inc.; Exelixis; Genentech, Inc.; Genmad; GlaxoSmithKline; Hoffman-La Roche Inc.; ImmunoGen, Inc.; Incyte Corporation; IOVANCE Biotherapeutics; Karyopharm; Leap Therapeutics, Inc.; Merck & Co.; Merck Sharp & Dohme Corp.; Mersana Therapeutics, Inc.; Novartis; NovoCure; NGR Oncology; OncoC4, Inc.; OncoQuest Inc.; Pfizer Inc.; Precision Theerapeutics, Inc.; Prelude Therapeutics; Regeneron Pharmaceuticals, Inc.; Rubius Therapeutics; Seagen Inc.; Sutro Biopharma; TESARO; Verastem, Inc.
Contracted researcher for: Abbvie; Advaxis; Agenus, Inc.; Alkermes; Aravive, Inc.; Arcus Biosciences, Inc.; AstraZeneca; Atossa Therapeutics; BeiGene USA, Inc.; Boston Biomedical; BristolMyersSquibb; Clovis Oncology; Deciphera Pharma; Eisai; EMD Serono, Inc.; Exelixis; Genentech, Inc.; Genmad; GlaxoSmithKline; Hoffman-La Roche Inc.; ImmunoGen, Inc.; Incyte Corporation; IOVANCE Biotherapeutics; Karyopharm; Leap Therapeutics, Inc.; Merck & Co.; Merck Sharp & Dohme Corp.; Mersana Therapeutics, Inc.; Novartis; NovoCure; NGR Oncology; OncoC4, Inc.; OncoQuest Inc.; Pfizer Inc.; Precision Theerapeutics, Inc.; Prelude Therapeutics; Regeneron Pharmaceuticals, Inc.; Rubius Therapeutics; Seagen Inc.; Sutro Biopharma; TESARO; Verastem, Inc.

Editor

Stephanie Baumhover, PharmD, BCPS

Medical Education Director, Medscape, LLC

Disclosures

Stephanie Baumhover, PharmD, BCPS, has no relevant financial relationships.

Compliance Reviewer

Leigh Schmidt, MSN, RN, CNE, CHCP

Associate Director, Accreditation and Compliance, Medscape, LLC

Disclosures

Leigh Schmidt, MSN, RN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

CME / ABIM MOC

Paris Pearls: Targeting Antibody-Drug Conjugates in Solid Tumors

Authors: Aditya Bardia, MD, MPH; Marina Garassino, MD; David O’Malley, MD
CME / ABIM MOC Released: 9/28/2022
THIS ACTIVITY HAS EXPIRED FOR CREDIT
Valid for credit through: 9/28/2023, 11:59 PM EST

Start Activity

Target Audience and Goal Statement

This activity is intended for oncologists, pathologists, obstetricians/gynecologists, pulmonologists, and other members of the multidisciplinary care team.

The goal of this activity is for learners to be better able to understand the latest data evaluating ADCs for the treatment of solid tumors and how best to incorporate these data into the clinical management of affected patients.

Upon completion of this activity, participants will:

Have increased knowledge regarding the
- Recent clinical trial data evaluating ADCs for the management of patients with solid tumors
Have greater competence related to
- Individualizing care for patients with solid tumors who would be eligible for ADC-directed therapy
Demonstrate greater confidence in their ability to
- Incorporate recent clinical trial data into the care of patients with solid tumors

Disclosures

Faculty

Aditya Bardia, MD, MPH

Director
Breast Cancer Research
Massachusetts General Hospital Cancer Center
Harvard Medical School
Boston, Massachusetts

Disclosures

Aditya Bardia, MD, MPH, has the following relevant financial relationships:
Consultant or advisor for: Daiichi Pharma/AstraZeneca; Eli Lilly; Foundation Medicine; Genentech; Immunomedics/Gilead; Merck; Novartis; Pfizer, Inc.; Phillips; Radius Health; Sanofi
Research funding from: Daiichi Pharma/AstraZeneca; Eli Lilly; Genentech; Immunomedics/Gilead; Merck; Novartis; Pfizer, Inc.; Radius Health; Sanofi

Marina Garassino, MD

Professor of Medicine
Lung Cancer Program of Chicago
Department of Hematology/Oncology
University of Chicago
Chicago, Illinois

Disclosures

Marina Garassino, MD, has the following relevant financial relationships:
Consultant or advisor for: AstraZeneca; Blueprint; Boehringer Ingelheim Italia; Bristol Myers Squibb Company; Celgene; Daiichi Sankyo; Ignyta; Incyte; Inivata; Janssen; Medimmune; Merck; Merck Sharp & Dohme, Corp.; Mirati; Novartis; Ose Immuno; Pfizer; Regeneron; Roche; Sanofi; Seattle Genetics; Takeda
Research funding from: AstraZeneca; Boehringer Ingelheim Italia; Bristol Myers Squibb Company; Celgene; Foundation Medicine; GlaxoSmithKline; Ignyta; Incyte; Lilly; Medimmune; Merck Sharp & Dohme, Corp.; Novartis; Pfizer; Roche; Spectrum; Takeda; Tiziana

David O’Malley, MD

Professor, Department of Obstetrics and Gynecology
The Ohio State University College of Medicine
Director, Division of Gynecologic Oncology
The Ohio State University Comprehensive Cancer Center
Columbus, Ohio

Disclosures

David O’Malley, MD, has the following relevant financial relationships:
Consultant or advisor for: AbbVie; AdaptImmune; Agenus, Inc.; Arquer Diagnostics; Arcus Biosciences, Inc.; AstraZeneca; Atossa Therapeutics; Boston Biomedical; Cardiff Oncology; Celcuity; Clovis Oncology; Corcept Therapeutics; Duality Bio; Eisai; Elevar; Exelixis; Genentech Inc.; Genelux; GlaxoSmithKline; Hoffmann-La Roche Inc.; ImmunoGen, Inc.; Imvax; InterVenn; INXMED; IOVANCE Biotherapeutics; Janssen; Jazz Pharmaceuticals; Laekna; Leap Therapeutics, Inc.; Luzsana Biotechnology; Merck & Co.; Merck Sharp & Dohme Corp.; Mersana Therapeutics, Inc.; Myriad; Novartis; NovoCure; OncoC4, Inc.; Onconova; Regeneron Pharmaceuticals, Inc.; RepImmune; R Pharm; Roche Diagnostics; Seagen Inc.; Sorrento; Sutro Biopharma; Tarveda Therapeutics; Toray; Trillium; Umoja; Verastem, Inc.; VBL Therapeutics; Vincerx Pharma; Zencor; Zentalis
Research funding from: Abbvie; Advaxis; Agenus, Inc.; Alkermes; Aravive, Inc.; Arcus Biosciences, Inc.; AstraZeneca; Atossa Therapeutics; BeiGene USA, Inc.; Boston Biomedical; BristolMyersSquibb; Clovis Oncology; Deciphera Pharma; Eisai; EMD Serono, Inc.; Exelixis; Genentech, Inc.; Genmad; GlaxoSmithKline; Hoffman-La Roche Inc.; ImmunoGen, Inc.; Incyte Corporation; IOVANCE Biotherapeutics; Karyopharm; Leap Therapeutics, Inc.; Merck & Co.; Merck Sharp & Dohme Corp.; Mersana Therapeutics, Inc.; Novartis; NovoCure; NGR Oncology; OncoC4, Inc.; OncoQuest Inc.; Pfizer Inc.; Precision Theerapeutics, Inc.; Prelude Therapeutics; Regeneron Pharmaceuticals, Inc.; Rubius Therapeutics; Seagen Inc.; Sutro Biopharma; TESARO; Verastem, Inc.
Contracted researcher for: Abbvie; Advaxis; Agenus, Inc.; Alkermes; Aravive, Inc.; Arcus Biosciences, Inc.; AstraZeneca; Atossa Therapeutics; BeiGene USA, Inc.; Boston Biomedical; BristolMyersSquibb; Clovis Oncology; Deciphera Pharma; Eisai; EMD Serono, Inc.; Exelixis; Genentech, Inc.; Genmad; GlaxoSmithKline; Hoffman-La Roche Inc.; ImmunoGen, Inc.; Incyte Corporation; IOVANCE Biotherapeutics; Karyopharm; Leap Therapeutics, Inc.; Merck & Co.; Merck Sharp & Dohme Corp.; Mersana Therapeutics, Inc.; Novartis; NovoCure; NGR Oncology; OncoC4, Inc.; OncoQuest Inc.; Pfizer Inc.; Precision Theerapeutics, Inc.; Prelude Therapeutics; Regeneron Pharmaceuticals, Inc.; Rubius Therapeutics; Seagen Inc.; Sutro Biopharma; TESARO; Verastem, Inc.

Editor

Stephanie Baumhover, PharmD, BCPS

Medical Education Director, Medscape, LLC

Disclosures

Stephanie Baumhover, PharmD, BCPS, has no relevant financial relationships.

Compliance Reviewer

Leigh Schmidt, MSN, RN, CNE, CHCP

Associate Director, Accreditation and Compliance, Medscape, LLC

Disclosures

Leigh Schmidt, MSN, RN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

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For Physicians

Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

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This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

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Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

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From Medscape Education Oncology

CME / ABIM MOC

Paris Pearls: Targeting Antibody-Drug Conjugates in Solid Tumors

Authors: Aditya Bardia, MD, MPH; Marina Garassino, MD; David O’Malley, MDFaculty and Disclosures

THIS ACTIVITY HAS EXPIRED FOR CREDIT

CME / ABIM MOC Released: 9/28/2022

Valid for credit through: 9/28/2023, 11:59 PM EST

processing....

Contents of This CME Activity

All sections of this activity are required for credit.

Targeting Antibody-Drug Conjugates in Breast Cancer

Dr Aditya Bardia discusses the latest data from ESMO 2022 on Antibody-Drug Conjugates in breast cancer.
Aditya Bardia, MD, MPH

Targeting Antibody-Drug Conjugates in Lung Cancer

Hear Dr Marina Garassino review the highlights of Antibody-Drug Conjugates in lung cancer from ESMO 2022.
Marina Garassino, MD

Targeting Antibody-Drug Conjugates in Ovarian Cancer

Dr David O’Malley summarizes the exciting developments using Antibody-Drug Conjugates in ovarian cancer from ESMO 2022.
David O’Malley, MD

Learning Feedback Questions

Please answer these questions to complement your learning experience.

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CME / ABIM MOC Information Download Slides

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Disclaimer

The educational activity presented above may involve simulated, case-based scenarios. The patients depicted in these scenarios are fictitious and no association with any actual patient, whether living or deceased, is intended or should be inferred. The material presented here does not necessarily reflect the views of Medscape, LLC, or any individuals or commercial entities that support companies that support educational programming on medscape.org. These materials may include discussion of therapeutic products that have not been approved by the US Food and Drug Administration, off-label uses of approved products, or data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal. Readers should verify all information and data before treating patients or employing any therapies described in this or any educational activity. A qualified healthcare professional should be consulted before using any therapeutic product discussed herein.

Faculty and Disclosures

Faculty

Aditya Bardia, MD, MPH

Marina Garassino, MD

David O’Malley, MD

Editor

Stephanie Baumhover, PharmD, BCPS

Compliance Reviewer

Leigh Schmidt, MSN, RN, CNE, CHCP

Peer Reviewer

CME / ABIM MOC

Paris Pearls: Targeting Antibody-Drug Conjugates in Solid Tumors

Target Audience and Goal Statement

Disclosures

Faculty

Aditya Bardia, MD, MPH

Marina Garassino, MD

David O’Malley, MD

Editor

Stephanie Baumhover, PharmD, BCPS

Compliance Reviewer

Leigh Schmidt, MSN, RN, CNE, CHCP

Peer Reviewer

Accreditation Statements

For Physicians

Instructions for Participation and Credit

Paris Pearls: Targeting Antibody-Drug Conjugates in Solid Tumors

Contents of This CME Activity

Targeting Antibody-Drug Conjugates in Breast Cancer

Targeting Antibody-Drug Conjugates in Lung Cancer

Targeting Antibody-Drug Conjugates in Ovarian Cancer

Learning Feedback Questions