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DOAC Reversal Agents: One Size Does Not Fit All

  • Authors: Jean M. Connors, MD; Gordon F. Tomaselli, MD
  • CME / ABIM MOC Released: 9/27/2022
  • Valid for credit through: 9/27/2023
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  • Credits Available

    Physicians - maximum of 0.25 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.25 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for cardiologists, emergency medicine physicians, and gastroenterologists. 

The goal of this activity is that learners will be better able to improve understanding of the role of DOAC specific reversal agents in the management of major DOAC-related bleeding.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Key differences between available reversal agents for DOAC therapy


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All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


  • Jean M. Connors, MD

    Medical Director, Hemostatic Antithrombotic Stewardship
    Medical Director, Anticoagulation Management Services (Hematology Division)
    Brigham and Women's Hospital/Dana-Farber Cancer Institute
    Associate Professor of Medicine
    Harvard Medical School
    Boston, Massachusetts


    Jean M. Connors, MD, has the following relevant financial relationships:                             
    Consultant or advisor for: Abbott Laboratories; Alnylam Pharmaceuticals; Anthos Therapeutic; Bristol-Myers Squibb; Pfizer; Sanofi S.A; Werfen
    Speaker or member of speakers bureau for: Roche; Sanofi S.A
    Research funding from: CSL Behring

  • Gordon F. Tomaselli, MD

    Marilyn and Stanley M. Katz Dean and Professor of Medicine (Cardiology)
    The Albert Einstein College of Medicine
    Executive Vice President and Chief
    Academic Officer 
    Montefiore Medicine
    Bronx, New York


    Gordon F. Tomaselli, MD, has no relevant financial relationships.


  • Asha P. Gupta, PharmD, RPh

    Associate Medical Education Director, Medscape, LLC


    Asha P. Gupta, PharmD, RPh, has no relevant financial relationships.

Compliance Reviewer

  • Lisa Simani, APRN, MS, ACNP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Lisa Simani, APRN, MS, ACNP, has no relevant financial relationships.

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    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.25 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

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For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

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There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

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*The credit that you receive is based on your user profile.


DOAC Reversal Agents: One Size Does Not Fit All

Authors: Jean M. Connors, MD; Gordon F. Tomaselli, MDFaculty and Disclosures

CME / ABIM MOC Released: 9/27/2022

Valid for credit through: 9/27/2023


A Powerpoint version of the slides from this presentation
is available for use as a professional resource from Medscape Education.

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