You are leaving Medscape Education
Cancel Continue
Log in to save activities Your saved activities will show here so that you can easily access them whenever you're ready. Log in here CME & Education Log in to keep track of your credits.


HR+/HER2- Early Breast Cancer: A Nurse Clinic on Monitoring and Communicating With Patients

  • Authors: Karen Drucker, RN, NP
  • CE Released: 9/26/2022
  • Valid for credit through: 9/26/2023, 11:59 PM EST
Start Activity

Target Audience and Goal Statement

This activity is intended for nurses, nurse practitioners, and physician assistants.

The goal of this activity is that learners will be better able to monitor and communicate with patients and implement practices that will improve adherence to adjuvant therapy for patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative EBC.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding
    • Nonadherence in patients with HR-positive, HER2-negative EBC treated with adjuvant therapy
    • Factors related to high risk of recurrence in patients with HR-positive, HER2-negative EBC
  • Have greater competence related to
    • Managing adverse events of oral adjuvant therapies used for HR-positive, HER2-negative EBC
  • Demonstrate greater confidence in their ability to
    • Communicate with patients to improve adherence to oral adjuvant therapy


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.

Disclosures for additional planners can be found here.


  • Karen Drucker, NP, RN

    Nurse Practitioner
    Evelyn H. Lauder Breast Center
    Memorial Sloan Kettering Cancer Center
    New York, New York


    Karen Drucker, RN, NP, has no relevant financial relationships.


  • Deborah Middleton, MS

    Senior Medical Education Director, WebMD Global, LLC


    Deborah Middleton, MS, has no relevant financial relationships.

Compliance Reviewer/Nurse Planner

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Stephanie Corder, ND, RN, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements


Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited with commendation by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Nurses

  • Awarded 0.25 contact hour(s) of nursing continuing professional development for RNs and APNs; 0.25 contact hour(s) are in the area of pharmacology.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


HR+/HER2- Early Breast Cancer: A Nurse Clinic on Monitoring and Communicating With Patients

Authors: Karen Drucker, RN, NPFaculty and Disclosures

CE Released: 9/26/2022

Valid for credit through: 9/26/2023, 11:59 PM EST


Susan is a 44-year-old, premenopausal woman with no family history of breast cancer. Genetic testing showed she is BRCA-negative. Diagnostic testing and imaging revealed locally advanced breast cancer. Her tumor was determined to be 5.5 cm, located in the left breast. The pathology results showed the tumor was estrogen receptor (ER)+ 90%, progesterone receptor (PR)+ 70%, human epidermal growth factor receptor 2 (HER2)-negative, Ki-67 22%. Susan underwent neoadjuvant therapy with dose-dense doxorubicin, cyclophosphamide, and paclitaxel (ddAC-T). She also underwent a left mastectomy and axillary lymph node dissection. Staging showed residual disease of ypT3N2. She completed her chemotherapy 3 months ago and radiation therapy 3 weeks ago and has now come to see her nurse practitioner.



  • Print