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Early Actors in Hereditary Angioedema Pathophysiology: Therapeutic Targets on the Horizon

  • Authors: Timothy Craig, FAACAI, FAAAAI, FACP, FACOI
  • CME / ABIM MOC Released: 9/15/2022
  • Valid for credit through: 9/15/2023, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for allergists and clinical immunologists, primary care physicians, and pediatricians.

The goal of this activity is that learners will be better able to identify novel HAE treatments and discuss their potential role in the treatment paradigm for HAE.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Pathophysiology of HAE
    • New treatment targets in HAE
    • Clinical data on emerging treatments
  • Demonstrate greater confidence in their ability to
    • Appreciate the role of emerging treatment targets for HAE management


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All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.

Disclosures for additional planners can be found here.


  • Timothy Craig, FAACAI, FAAAAI, FACP, FACOI

    Professor of Medicine, Pediatrics, Biomedical Sciences
    Director, ACARE Center of Excellence for Angioedema
    Director, Alpha-1-Antitrypsin Deficiency Center
    Director, AI and Respiratory Clinical Research
    The Pennsylvania State University
    Hershey, Pennsylvania


    Timothy Criag, FAACAI, FAAAAI, FACP, FACOI, has the following relevant financial relationships:
    Consultant or advisor for: Biocryst; BioMarin; CSL Behring; Grifols; Regeneron; Takeda
    Speaker or member of speakers bureau for: CSL Behring; Grifols; Takeda
    Research funding from: Biocryst; BioMarin; CSL Behring; GlaxoSmithKline; Grifols; Ionis; Kalistor; Pharvaris; Regeneron; Takeda


  • Stuart Crayford, MSc, LLM

    Senior Director, Content Development, WebMD Global, LLC


    Stuart Crayford, MSc, LLM, has no relevant financial relationships.

  • Chii Shyang Fong, PhD

    Scientific Content Manager, WebMD Global, LLC


    Chii Shyang Fong, PhD, has no relevant financial relationships.

Compliance Reviewer

  • Leigh Schmidt, MSN, RN, CNE, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Leigh Schmidt, MSN, RN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

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    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

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Early Actors in Hereditary Angioedema Pathophysiology: Therapeutic Targets on the Horizon

Authors: Timothy Craig, FAACAI, FAAAAI, FACP, FACOIFaculty and Disclosures

CME / ABIM MOC Released: 9/15/2022

Valid for credit through: 9/15/2023, 11:59 PM EST


A Powerpoint version of the slides from this presentation
is available for use as a professional resource from Medscape Education.

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