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Watching Out for Wilson Disease: Overcoming Diagnostic Challenges

  • Authors: Caitlin Mulligan, MD; Michael L. Schilsky, MD, FAASLD; Nadia Ovchinsky, MD, MBA, FAASLD
  • CME / ABIM MOC Released: 9/20/2022
  • Valid for credit through: 9/20/2023, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for physicians who may encounter patients with WD, including gastroenterologists, neurologists, pediatricians, psychiatrists, and ophthalmologists.

The goals of this activity are that learners will be better able to recognize clinical signs and symptoms and red flag findings indicative of WD to improve timely diagnosis and initiation of treatment, and to discuss guideline recommendations for diagnosis of WD and implications for improved diagnosis in clinical practice.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Clinical presentation of WD
    • Diagnostic strategies to improve timely and accurate diagnosis of WD
    • Treatment options for WD


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships.


  • Caitlin Mulligan, MD

    Assistant Clinical Professor
    Department of Neurosciences
    University of California, San Diego
    La Jolla, California


    Caitlin Mulligan, MD, has no relevant financial relationships.

  • Michael L. Schilsky, MD, FAASLD

    Professor of Medicine and Surgery
    Yale University
    Center for Excellence for Wilson Disease at Yale
    New Haven, Connecticut


    Michael L. Schilsky, MD, FAASLD, has no relevant financial relationships.

  • Nadia Ovchinsky, MD, MBA, FAASLD

    Professor of Pediatrics
    Albert Einstein College of Medicine
    Director, Pediatric Hepatology
    Medical Director, Pediatric Liver Transplant
    Children's Hospital at Montefiore
    Bronx, New York


    Nadia Ovchinsky, MD, MBA, FAASLD, has the following relevant financial relationships:
    Consultant or advisor for: Albireo Pharma
    Research funding from: Albireo Pharma; Mirum Pharmaceuticals; Travere Therapeutics


  • Frances McFarland, PhD, MA

    Associate Medical Education Director, Medscape, LLC


    Frances McFarland, PhD, MA, has no relevant financial relationships.

Compliance Reviewer

  • Susan L. Smith, MN, PhD

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Susan L. Smith, MN, PhD, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements


Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

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For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

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  1. Read the target audience, learning objectives, and author disclosures.
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Watching Out for Wilson Disease: Overcoming Diagnostic Challenges

Authors: Caitlin Mulligan, MD; Michael L. Schilsky, MD, FAASLD; Nadia Ovchinsky, MD, MBA, FAASLDFaculty and Disclosures

CME / ABIM MOC Released: 9/20/2022

Valid for credit through: 9/20/2023, 11:59 PM EST


A Powerpoint version of the slides from this presentation
is available for use as a professional resource from Medscape Education.

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