You are leaving Medscape Education
Cancel Continue
Log in to save activities Your saved activities will show here so that you can easily access them whenever you're ready. Log in here CME & Education Log in to keep track of your credits.


Advancements in Bipolar Disorder

  • Authors: Leslie Citrome, MD, MPH; Holly A. Swartz, MD 
  • CME / ABIM MOC / CE Released: 7/7/2022
  • Valid for credit through: 7/7/2023, 11:59 PM EST
Start Activity

Target Audience and Goal Statement

This activity is intended for psychiatrists, primary care physicians (PCPs), pediatricians, nurses, nurse practitioners (NPs), and physician assistants (PAs).

The goal of this activity is that learners will be better able to screen, diagnose, and treat bipolar disorder.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Recent clinical trial data on emerging and novel therapeutics indicated for bipolar disorders 
  • Have greater competence related to
    • Accurately identifying depressive episodes related to mood disorders across the spectrum


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Medscape policies. Others involved in the planning of this activity have no relevant financial relationships. Disclosures for additional planners can be found here.


  • Leslie Citrome, MD, MPH

    Clinical Professor
    Psychiatry and Behavioral Sciences
    New York Medical College
    Valhalla, New York


    Leslie Citrome, MD, MPH, has the following relevant financial relationships:
    Consultant or advisor for: AbbVie/Allergan; Acadia; Adamas; Alkermes; Angelini; Astellas; Avanir; Axsome; BioXcel; Boehringer Ingelheim; Cadent Therapeutics; Eisai; Enteris BioPharma; HLS Therapeutics; Impel; Intra-Cellular Therapies; Janssen; Karuna; Lundbeck; Lyndra; Medavante-ProPhase; Merck; Neurocrine; Novartis; Noven; Otsuka; Ovid; Relmada; Reviva; Sage; Sunovion; Supernus; Teva
    Speaker or member of speakers bureau for: AbbVie/Allergan; Acadia; Alkermes; Angelini; Eisai; Intra-Cellular Therapies; Janssen; Lundbeck; Neurocrine; Noven; Otsuka; Sage; Sunovion; Takeda; Teva
    Stock options from: Reviva
    Owns stock (publicly traded) in: Bristol Myers Squibb; Eli Lilly and Company; Johnson & Johnson; Merck; Pfizer

  • Holly A. Swartz, MD

    Professor of Psychiatry
    University of Pittsburgh
    American Journal of Psychotherapy
    International Society for Bipolar Disorders
    Pittsburgh, Pennsylvania


    Holly A. Swartz, MD, has the following relevant financial relationships:
    Consultant or advisor for: Intra-Cellular Therapeutics


  • Faisal Islam, MD, MBA

    Medical Education Director, Medscape, LLC


    Faisal Islam, MD, MBA, has no relevant financial relationships.

Compliance Reviewer/Nurse Planner

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC 


    Stephanie Corder, ND, RN, CHCP, has no relevant financial relationships. 

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements


Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 1.00  AMA PRA Category 1 Credits ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.00 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity. 

    Contact This Provider

    For Nurses

  • Awarded 1.00 contact hour(s) of nursing continuing professional development for RNs and APNs; 0.50 contact hours are in the area of pharmacology.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


Advancements in Bipolar Disorder

Authors: Leslie Citrome, MD, MPH; Holly A. Swartz, MD Faculty and Disclosures

CME / ABIM MOC / CE Released: 7/7/2022

Valid for credit through: 7/7/2023, 11:59 PM EST


Contents of This CME Activity

All sections of this activity are required for credit.

Don’t Miss the Diagnosis: Differentiating Bipolar Depression

What are the consequences of misdiagnosis? Dr Citrome discusses how to avoid common pitfalls.
Leslie Citrome, MD, MPH

Bipolar Spectrum Disorders: Individualizing Treatment and Updates in Advancements

Efficacious and safe options are available now and on the horizon.
Holly A. Swartz, MD

Educational Impact Challenge

The goal of this activity is that learners will be better able to screen, diagnose, and treat bipolar disorder.

Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.

  • Print