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CPD

Wilson Disease: The Great Masquerader

  • Authors: Karl Heinz Weiss, MD; Anil Dhawan, MBBS, MD, FRCPCH; Aurélia Poujois, MD, PhD; Paula C. Zimbrean, MD, FAPA, FACLP
  • CPD Released: 6/30/2022
  • THIS ACTIVITY HAS EXPIRED FOR CREDIT
  • Valid for credit through: 6/30/2023, 11:59 PM EST
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Target Audience and Goal Statement

This educational activity is intended for an international audience of non-US neurologists, gastroenterologists, psychiatrists, pediatricians, and primary care physicians.

The goal of this activity is that learners will be better able to recognize the different clinical manifestations of WD and improve timely diagnosis.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding
    • The presentation of WD in different clinical settings
    • Copper metabolism
    • Diagnostic strategies for WD


Disclosures

WebMD Global requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships with ineligible companies.


Faculty

  • Karl Heinz Weiss, MD

    Professor of Internal Medicine and Gastroenterology
    Chief Physician of the Medical Clinic
    Salem Hospital
    Heidelberg, Germany

    Disclosures

    Karl Heinz Weiss, MD, has the following relevant financial relationships:
    Consultant or advisor for: Alexion Pharmaceuticals, Inc.; Bayer; Orphalan; Pfizer, Inc.; Ultragenyx; Univar Solutions; Vivet Therapeutics

  • Anil Dhawan, MBBS, MD, FRCPCH

    Professor of Pediatric Hepatology
    King's College London
    London, United Kingdom

    Disclosures

    Anil Dhawan, MBBS, MD, FRCPCH, has no relevant financial relationships.

  • Aurélia Poujois, MD, PhD

    Neurologist
    Head of the Rare Disease Reference Centre
    "Wilson's Disease and Other Copper-Related Rare Diseases"
    Hôpital Fondation Adolphe de Rothschild
    Paris, France

    Disclosures

    Aurélia Poujois, MD, PhD, has the following relevant financial relationships:
    Consultant or advisor for: Alexion Pharmaceuticals, Inc.; Orphalan; Univar Solutions; Vivet Therapeutics
    Speaker or member of speakers bureau for: Alexion Pharmaceuticals, Inc.; Orphalan; Univar Solutions
    Research funding from: AddMedica; Merz Pharmaceuticals; Orphalan

  • Paula C. Zimbrean, MD, FAPA, FACLP

    Associate Professor of Psychiatry and Surgery
    Yale University School of Medicine
    New Haven, Connecticut, United States

    Disclosures

    Paula C. Zimbrean, MD, FAPA, FACLP, has the following relevant financial relationships:
    Consultant or advisor for: Alexion Pharmaceuticals, Inc.; Ultragenyx; Vivet Therapeutics
    Research funding from: Alexion Pharmaceuticals, Inc.
    Contracted researcher for: Alexion Pharmaceuticals, Inc.

Editors

  • Maya Khalaf, MSc

    Associate Medical Education Director, WebMD Global, LLC

    Disclosures

    Maya Khalaf, MSc, has no relevant financial relationships.

  • Marinella Calle, PhD, CMPP

    Medical Education Director, WebMD Global, LLC 

    Disclosures

    Marinella Calle, PhD, CMPP, has no relevant financial relationships.

  • Diana Lucifero, PhD

    Scientific Content Manager, WebMD Global, LLC 

    Disclosures

    Diana Lucifero, PhD, has no relevant financial relationships.

Compliance Reviewer

  • Susan L. Smith, MN, PhD

    Associate Director, Accreditation and Compliance

    Disclosures

    Susan L. Smith, MN, PhD, has no relevant financial relationships.

Peer Reviewer:

This activity has been peer reviewed and the reviewer has no relevant financial relationships.


Accreditation Statements

    For Physicians

  • The Faculty of Pharmaceutical Medicine of the Royal Colleges of Physicians of the United Kingdom (FPM) has reviewed and approved the content of this educational activity and allocated it 0.75 continuing professional development credits (CPD).

    Contact WebMD Global

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information about your eligibility to claim credit, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent participating in the activity. To successfully earn credit, participants must complete the activity online during the credit eligibility period that is noted on the title page.

Follow these steps to claim a credit certificate for completing this activity:

  1. Read the information provided on the title page regarding the target audience, learning objectives, and author disclosures, read and study the activity content and then complete the post-test questions. If you earn a passing score on the post-test and we have determined based on your registration profile that you may be eligible to claim CPD credit for completing this activity, we will issue you a CPD credit certificate.
  2. Once your CPD credit certificate has been issued, you may view and print the certificate from your CME/CE Tracker. CPD credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates by accessing "Edit Your Profile" at the top of the Medscape Education homepage.

We encourage you to complete an Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates by accessing "Edit Your Profile" at the top of your Medscape homepage.

*The credit that you receive is based on your user profile.

CPD

Wilson Disease: The Great Masquerader

Authors: Karl Heinz Weiss, MD; Anil Dhawan, MBBS, MD, FRCPCH; Aurélia Poujois, MD, PhD; Paula C. Zimbrean, MD, FAPA, FACLPFaculty and Disclosures
THIS ACTIVITY HAS EXPIRED FOR CREDIT

CPD Released: 6/30/2022

Valid for credit through: 6/30/2023, 11:59 PM EST

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Contents of This CPD Activity

All sections of this activity are required for credit.

Wilson Disease and Copper Metabolism

Dr Weiss introduces WD and its underlying defects in copper metabolism.
Karl Heinz Weiss, MD

Clinical Presentation of Wilson Disease in a Hepatology Setting

Learn about the spectrum of liver disease observed in patients with WD.
Karl Heinz Weiss, MD

Clinical Presentation of Wilson Disease in a Pediatric Setting

Dr Dhawan describes the important features of how WD commonly presents in children.
Anil Dhawan, MBBS, MD, FRCPCH

Clinical Presentation of Wilson Disease in a Neurology Setting

From dystonia to ophthalmologic features, learn more about the neurologic symptoms of WD.
Aurélia Poujois, MD, PhD

Clinical Presentation of Wilson Disease in a Psychiatry Setting

Join Dr Zimbrean as she describes the spectrum of psychiatric symptoms that may occur at any stage of WD.
Paula C. Zimbrean, MD, FAPA, FACLP

Strategies for Diagnosing Wilson Disease

Dr Poujois concludes with a summary of key diagnostic tools and strategies that can help diagnose WD.
Aurélia Poujois, MD, PhD
 

Educational Impact Challenge

The goal of this activity is that learners will be better able to recognize the different clinical manifestations of WD and improve timely diagnosis.

Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.

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