You are leaving Medscape Education
Cancel Continue
Log in to save activities Your saved activities will show here so that you can easily access them whenever you're ready. Log in here CME & Education Log in to keep track of your credits.
 

CPD

Challenging Cases of Glomerulonephritis: How Would You Diagnose and Manage These Patients?

  • Authors: Fadi Fakhouri, MD, PhD
  • CPD Released: 7/15/2022
  • THIS ACTIVITY HAS EXPIRED FOR CREDIT
  • Valid for credit through: 7/15/2023, 11:59 PM EST
Start Activity


Target Audience and Goal Statement

This educational activity is intended for an international audience of non-US primary care providers (PCPs), nephrologists, and allergists & clinical immunologists.

The goals of this activity are that learners will better understand best practices for evaluation, diagnosis, differential diagnosis, and management of rare complement-mediated kidney diseases and the challenges and limitations of current standard of care.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Clinical manifestations of rare complement-mediated kidney diseases
  • Have greater competence related to
    • Diagnosis of rare complement-mediated kidney diseases
    • Management of rare complement mediated kidney diseases


Disclosures

WebMD Global requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated. Others involved in the planning of this activity have no relevant financial relationships with ineligible companies.


Faculty

  • Fadi Fakhouri, MD, PhD

    Professor of Nephrology
    CHUV, UNIL Lausanne
    Lausanne, Switzerland

    Disclosures

    Fadi Fakhouri, MD, PhD, has the following relevant financial relationships: 
    Consultant or advisor for: Alexion; Apellis; Novartis; Roche

Editors

  • Rita Moreira Da Silva, PhD, MA, PharmD

    Medical Education Director, WebMD Global, LLC

    Disclosures

    Rita Moreira Da Silva, PhD, MA, PharmD, has no relevant financial relationships.

  • Gina Montanero, PharmD

    Associate Medical Writer, Medscape, LLC

    Disclosures

    Gina Montanero, PharmD, has no relevant financial relationships.

Compliance Reviewer

  • Susan L. Smith, MN, PhD

    Associate Director, Accreditation and Compliance

    Disclosures

    Susan L. Smith, MN, PhD, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.


Accreditation Statements

    For Physicians

  • The Faculty of Pharmaceutical Medicine of the Royal Colleges of Physicians of the United Kingdom (FPM) has reviewed and approved the content of this educational activity and allocated it 1.0 continuing professional development credits (CPD).

    Contact WebMD Global

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information about your eligibility to claim credit, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent participating in the activity. To successfully earn credit, participants must complete the activity online during the credit eligibility period that is noted on the title page.

Follow these steps to claim a credit certificate for completing this activity:

  1. Read the information provided on the title page regarding the target audience, learning objectives, and author disclosures, read and study the activity content and then complete the post-test questions. If you earn a passing score on the post-test and we have determined based on your registration profile that you may be eligible to claim CPD credit for completing this activity, we will issue you a CPD credit certificate.
  2. Once your CPD credit certificate has been issued, you may view and print the certificate from your CME/CE Tracker. CPD credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates by accessing "Edit Your Profile" at the top of the Medscape Education homepage.

We encourage you to complete an Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates by accessing "Edit Your Profile" at the top of your Medscape homepage.

*The credit that you receive is based on your user profile.

CPD

Challenging Cases of Glomerulonephritis: How Would You Diagnose and Manage These Patients?

Authors: Fadi Fakhouri, MD, PhDFaculty and Disclosures
THIS ACTIVITY HAS EXPIRED FOR CREDIT

CPD Released: 7/15/2022

Valid for credit through: 7/15/2023, 11:59 PM EST

processing....

The following cases are modeled on the interactive grand rounds approach. The questions within the activity are designed to test your current knowledge. After each question, you will be able to see whether you answered correctly and read evidence-based information that supports the most appropriate answer choice. The questions are designed to challenge you; you will not be penalized for answering the questions incorrectly. At the end of the activity, there will be a short post-test assessment based on the material presented.

Case 1: Joseph, a 50-year-old man with hypertension.

Joseph is a 50-year-old financial consultant with a history of hypertension. He is referred to a nephrologist for a mild increase in serum creatinine (sCr) and elevated blood pressure of 148/98 mm/Hg. His medical history and the results of his physical exam and laboratory tests are shown in Table 1.

You note his elevated blood pressure despite adherence to an angiotensin converting enzyme (ACE) inhibitor and diuretic. Analysis of his renal function shows proteinuria, hematuria, and mildly increased sCr.

 

Table 1. Joseph’s Medical Record

History Findings
Medical Controlled hypertension x 15 years, recently became elevated despite treatment
Current Medications Lisinopril 20 mg/d, hydrochlorothiazide 25 mg/d, simvastatin 20 mg/d
Social/Occupational Financial consultant, married, lives with wife and dog; non-smoker, non-drinker; has 2 adult daughters; on Dietary Approaches to Stop Hypertension (DASH) diet and walks 3 times a week
Physical exam Findings
Vital Signs BP: 148/98 mmHg
HR: 78 bpm
Body measurements Weight 76 kg, BMI = 24 kg/m2
Extremities No edema
Neck No distended neck veins
Heart LVEF = 60%
Lungs No rales
Abdomen Soft, nontender
CBC Results
  Normal
Metabolic Panel Results
FPG 90 mg/dL
HbA1c 6.8%
Lipid panel LDL: 70 mg/dL; HDL: 35 mg/dL; TG: 155 mg/dL
Kidney Panel  
eGFR 55 mL/min/1.73 m2
UACR 200 mg/g
Serum Creatinine 1.5 mg/dL
Urine dipstick +WBC, +RBC
BMI, body mass index; BP, blood pressure; CBC, complete blood count; eGFR, estimated glomerular filtration rate; FPG, fasting plasma glucose; HDL, high density lipoprotein; HTN, hypertension; HR, heart rate; LVEF, left ventricular ejection fraction; LDL, low density lipoprotein; RBC, red blood cell; TG, triacylglycerol; UACR, urine albumin-to-creatinine ratio; WBC, white blood cell.
  • Print