You are leaving Medscape Education
Cancel Continue
Log in to save activities Your saved activities will show here so that you can easily access them whenever you're ready. Log in here CME & Education Log in to keep track of your credits.


On the Cusp: Evaluating the Intricacies of Hematopoietic Stem Cell Transplant and Gene Therapy for Hemoglobinopathies

  • Authors: Alexis Thompson, MD, MPH
  • CME Released: 6/10/2022
  • Valid for credit through: 6/10/2023, 11:59 PM EST
Start Activity

Target Audience and Goal Statement

This activity is intended for hematologists/oncologists, transplant specialists, pediatricians, and other healthcare providers involved in the care of patients with hemoglobinopathies.

The goal of this activity is that learners will improve their understanding of current and emerging treatment modalities for patients with hemoglobinopathies and their ability to manage these patients.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Different gene therapy mechanisms
    • Role of hemoglobin subtypes in the mechanism of gene therapies
    • Long-term follow-up data for patients treated with gene therapy
  • Have greater competence related to
    • Assessing patient eligibility for curative options for hemoglobinopathies


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Medscape policies. Others involved in the planning of this activity have no relevant financial relationships.


  • Alexis Thompson, MD, MPH

    Professor of Pediatrics
    Perelman School of Medicine
    Chief, Division of Hematology
    Children's Hospital of Philadelphia
    University of Pennsylvania
    Philadelphia, Pennsylvania


    Disclosure: Alexis Thompson, MD, MPH, has the following relevant financial relationships:
    Consultant or advisor for: Agios; bluebird bio Inc; Celgene/Bristol Myers Squibb; CRISPR/Vertex
    Research funding from: Baxalta; BioMarin Pharmaceutical Inc.; bluebird bio Inc; Celgene/Bristol Myers Squibb; CRISPR/Vertex; Editas Medicine Inc; Novartis
    Stock options from: Global Blood Therapeutics


  • Deborah Middleton, MS

    Senior Medical Education Director, WebMD Global, LLC


    Disclosure: Deborah Middleton, MS, has no relevant financial relationships.

Compliance Reviewer

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Disclosure: Stephanie Corder, ND, RN, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.

Accreditation Statements

Developed through a partnership between Medscape and the Medical College of Wisconsin (MCW).

    For Physicians

  • The Medical College of Wisconsin is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

    The Medical College of Wisconsin designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


On the Cusp: Evaluating the Intricacies of Hematopoietic Stem Cell Transplant and Gene Therapy for Hemoglobinopathies

Authors: Alexis Thompson, MD, MPHFaculty and Disclosures

CME Released: 6/10/2022

Valid for credit through: 6/10/2023, 11:59 PM EST


A Powerpoint version of the slides from this presentation
is available for use as a professional resource from Medscape Education.

  • Print