This educational activity is intended for an international audience of psychiatrists, primary care physicians, and neurologists practicing in Europe, the Middle East, and North Africa.
The goal of this activity is that learners will be better able to determine which patients with major depressive disorder (MDD) and treatment-resistant depression (TRD) may benefit from treatment that targets the glutamate receptor.
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CPD Released: 5/2/2022
Valid for credit through: 5/2/2023
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The following cases are modeled on the interactive grand rounds approach. The questions within the activity are designed to test your current knowledge. After each question, you will be able to see whether you answered correctly and read evidence-based information that supports the most appropriate answer choice. The questions are designed to challenge you; you will not be penalized for answering the questions incorrectly. At the end of the activity, there will be a short post-test assessment based on the material presented.
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Arnold is a 53-year-old truck driver and has major depressive disorder (MDD). He previously received treatment with 2 antidepressants and cognitive behavioral therapy (CBT). In his current depressive episode, he received citalopram, followed by sertraline, combined with CBT. Arnold is divorced, and he can no longer support his 2 children who live with his former partner. He is struggling at work and has moved from job to job over the years. Arnold has hypertension and hypercholesterolemia, both of which are controlled with medication. He also has a history of traumatic brain injury following an accident 4 years ago, and he is recovering from an addiction to prescription painkillers. He presents with ongoing symptoms of anhedonia, fatigue, depressed mood, and lack of energy.