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Micro-Lessons in Heart Transplant Monitoring

  • Authors: Shelley Hall, MD; Josef Stehlik, MD, MPH; Jon A. Kobashigawa, MD
  • CME / ABIM MOC Released: 4/22/2022
  • Valid for credit through: 4/22/2023
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  • Credits Available

    Physicians - maximum of 0.50 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.50 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for cardiologists, transplant surgeons, and other healthcare providers who work with patients who have received a heart transplant.

The goal of this activity is that learners will have improved knowledge of current recommendations for monitoring for rejection, including use of available noninvasive technologies, after heart transplantation.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Advantages and limitations of endomyocardial biopsy (EMB)
    • Donor-derived cell-free DNA (dd-cfDNA) in heart transplant rejection monitoring
    • Gene expression profiling (GEP) in heart transplant rejection monitoring
    • Other noninvasive testing options for acute rejection
    • Research into biomarkers for heart transplant rejection surveillance


Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Medscape policies. Others involved in the planning of this activity have no relevant financial relationships.



  • Shelley Hall, MD

    Chief of Transplant Cardiology & Mechanical Support/Heart Failure
    Clinical Assistant Professor (Affiliated)
    Texas A&M Health Science Center, College of Medicine
    Chair, UNOS Cardiac Committee
    Chair, Thoracic and Critical Care Council of Practice, AST
    President, Texas Chapter, ACC
    Baylor University Medical Center
    Dallas, Texas


    Consultant or advisor for: Abbott; Abiomed; CareDx; Medtronic; Natera
    Research funding from: Abbott; Abiomed; CareDx; Medtronic; Natera; Novartis

  • Josef Stehlik, MD, MPH

    Christi T Smith Professor Medicine
    University of Utah Health
    Division of Cardiovascular Medicine
    Salt Lake City, Utah


    Consultant or advisor for: Medtronic; Natera; Sanofi; Transmedics
    Research funding from: Natera

  • Jon A. Kobashigawa, MD

    DSL/Thomas D. Gordon Professor of Medicine
    Director, Advanced Heart Disease Division
    Director, Heart Transplant Program
    Associate Director, Smidt Heart Institute
    Associate Director, Comprehensive Transplant Center
    Cedars-Sinai Medical Center
    Los Angeles, California


    Consultant or advisor for: CareDx; Novartis; Sanofi
    Research funding from: CareDx; CSL Behring; Sanofi; TransMedics


  • Joy P. Marko, MS, APN-C, CCMEP

    Senior Medical Education Director, Medscape, LLC 


    Disclosure: Joy P. Marko, MS, APN-C, CCMEP, has no relevant financial relationships.

  • Frederick Stange, DO

    Scientific Content Manager, Medscape, LLC  


    Disclosure: Frederick Stange, DO, has no relevant financial relationships. 

Compliance Reviewer

  • Susan L. Smith, MN, PhD

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Disclosure: Susan L. Smith, MN, PhD, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has no relevant financial relationships.

Accreditation Statements

In support of improving patient care, Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.


Micro-Lessons in Heart Transplant Monitoring

Authors: Shelley Hall, MD; Josef Stehlik, MD, MPH; Jon A. Kobashigawa, MDFaculty and Disclosures

CME / ABIM MOC Released: 4/22/2022

Valid for credit through: 4/22/2023


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