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CME / ABIM MOC

Caring for Pediatric Patients With NTRK Fusion-Positive Tumors: Strategies to Optimize Your Practice

  • Authors: Theodore Laetsch, MD; James P. Solomon, MD, PhD; Steven DuBois, MD, MS
  • CME / ABIM MOC Released: 4/20/2022
  • Valid for credit through: 4/20/2023
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  • Credits Available

    Physicians - maximum of 0.50 AMA PRA Category 1 Credit(s)™

    ABIM Diplomates - maximum of 0.50 ABIM MOC points

    You Are Eligible For

    • Letter of Completion
    • ABIM MOC points

Target Audience and Goal Statement

This activity is intended for hematology/oncology (hem/onc) specialists, pathologists, and pediatricians.

The goal of this activity is that the learner will be better able to understand and manage pediatric NTRK fusion-positive cancers.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Data from recent clinical studies in pediatric NTRK fusion-positive cancers
  • Have greater competence related to
    • Personalizing care for children and adolescent patients with an NTRK fusion-positive cancer
  • Demonstrate greater confidence in their ability to
    • Communicate effectively with patients and caregivers about potential treatment-related adverse events associated with tropomyosin receptor kinase (TRK) inhibitors


Disclosures

Medscape, LLC requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Medscape policies. Others involved in the planning of this activity have no relevant financial relationships.


Faculty

  • Theodore Laetsch, MD

    Associate Professor
    Department of Pediatrics
    Abramson Cancer Center
    Perelman School of Medicine
    University of Pennsylvania
    Director
    Developmental Therapeutics and Rare Tumor Program
    Division of Oncology
    Center for Childhood Cancer Research
    Children's Hospital of Philadelphia
    Philadelphia, Pennsylvania

    Disclosures

    Disclosure: Theodore Laetsch, MD, has the following relevant financial relationships:
    Advisor or consultant for: Bayer; Cellectis; Deciphera Pharmaceuticals, Inc.; Jumo; Massive Bio; Y-mAbs Therapeutics
    Grants for clinical research from: Bayer; Novartis; Pfizer, Inc.

  • James P. Solomon, MD, PhD

    Medical Director
    Clinical Genomics Laboratory
    Assistant Professor
    Pathology and Laboratory Medicine
    Assistant Attending Pathologist
    Department of Pathology and Laboratory Medicine
    Weill Cornell Medicine
    New York, New York

    Disclosures

    Disclosure: James P. Solomon, MD, PhD, has the following relevant financial relationships:
    Stocks, stock options, or bonds from: AmerisourceBergen; Bionano Genomics; Clover Biopharmaceuticals; CRISPR Therapeutics; Guardant Health, Inc.; Merck; Pfizer, Inc.; Vertex Pharmaceuticals Incorporated

  • Steven DuBois, MD, MS

    Associate Professor
    Pediatrics
    Harvard Medical School
    Director
    Experimental Therapeutics for Pediatric Oncology
    Dana-Farber Cancer Institute
    Boston, Massachusetts

    Disclosures

    Disclosure: Steven DuBois, MD, MS, has the following relevant financial relationships:
    Advisor or consultant for: Amgen, Inc.; Bayer
    Other: Travel expenses from: Loxo Oncology; Roche; Salarius Pharmaceuticals

Editor

  • Lisa M. Cockrell, PhD

    Medical Education Director, Medscape, LLC

    Disclosures

    Disclosure: Lisa M. Cockrell, PhD, has disclosed no relevant financial relationships.

Compliance Reviewer

  • Leigh Schmidt, MSN, RN, CMSRN, CNE, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Disclosure: Leigh Schmidt, MSN, RN, CMSRN, CNE, CHCP, has no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.


Accreditation Statements



In support of improving patient care, Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read about the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or print it out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate, but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period, you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / ABIM MOC

Caring for Pediatric Patients With NTRK Fusion-Positive Tumors: Strategies to Optimize Your Practice

Authors: Theodore Laetsch, MD; James P. Solomon, MD, PhD; Steven DuBois, MD, MSFaculty and Disclosures

CME / ABIM MOC Released: 4/20/2022

Valid for credit through: 4/20/2023

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Educational Impact Challenge

The goal of this activity is that the learner will be better able to understand and manage pediatric NTRK fusion-positive cancers.

Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.