Physicians - maximum of 1.00 AMA PRA Category 1 Credit(s)™
ABIM Diplomates - maximum of 1.00 ABIM MOC points
This activity is intended for infectious disease clinicians, internists, intensivists, geriatricians, public health officials, and other clinicians who treat and manage patients with or at risk for Shewanella spp. bloodstream infections.
The goal of this activity is to describe the incidence of and risk factors for development of Shewanella spp. bloodstream infections, based on findings of a population-based surveillance study in Queensland, Australia, during 2000-2019.
Upon completion of this activity, participants will:
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CME / ABIM MOC Released: 3/17/2022
Valid for credit through: 3/17/2023
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The epidemiology of bloodstream infections caused by Shewanella spp. is not well defined. Our objective was to define the incidence and determinants of Shewanella spp. bloodstream infections by using population-based surveillance in Queensland, Australia during 2000‒2019. The incidence was 1.0 cases/1 million persons annually and was highest during summer and in the tropical Torres and Cape region. Older persons and male patients were at highest risk. At least 1 concurrent condition was documented in 75% of case-patients, and 30-day all cause case-fatality rate was 15%. Aging populations in warm climates might expect an increasing burden of these infections.
Shewanella spp., most commonly S. algae and S. putrefaciens, are infrequent but occasionally severe causes of human infection associated with exposure to warm marine environments[1,2]. Cases of otogenic and skin and soft tissue infections caused by S. (Pseudomonas) putrefaciens were described in the 1960s, and case series of bacteremic infections were reported in subsequent decades[3,4]. Vignier et al. reported 16 cases of Shewanella spp. infection that occurred in Martinique during 1997–2012 and identified an additional 239 cases in review of the published literature during 1973–2011[5]. That study observed that otogenic, skin and soft tissue, abdominal/biliary tract, and respiratory tract foci of infection were most common, and that 71 (28%) cases were bacteremic[5]. Shewanella spp. are frequently coisolated with other organisms, most notably Enterobacterales and Aeromonas and Vibrio spp., and occasionally might develop major antimicrobial drug resistance[2,5,6].
As a result of their rarity, the epidemiology of Shewanella spp. bloodstream infections (BSIs) is poorly defined. The existing body of literature is limited to case reports and small series. In addition, as a result of developments in genomic and phenotypic testing, it has been recognized that before the current millennium many reports of S. putrefaciens infection might have been actually caused by S. algae[7]. The objective of this study was to determine the contemporary incidence of and risk factors for development of Shewanella spp. BSIs in the population of Queensland, Australia.