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Systemic Lupus Erythematosus: Micro Lessons on the Future of Biologics

  • Authors: Edith M. Williams, PhD, MS; Michelle Petri, MD, MPH; Richard Furie, MD
  • CME Released: 2/23/2022
  • Valid for credit through: 2/23/2023, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for rheumatologists and primary care physicians. 

The goal of this activity is that learners will be better able to identify the risks of long-term dependence on conventional immunosuppressive treatments in managing systemic lupus erythematosus (SLE) and have improved knowledge regarding the role of biologic therapies in SLE treatment.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Patient burden associated with disease progression and drug side effects
    • Risks of long-term glucocorticoid use in SLE management
    • Targets of novel and established biological therapies for SLE treatment
    • Most recent clinical trial data on targeted therapies for SLE management
    • Application of biologics in practice when treating SLE


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All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Medscape policies. Others involved in the planning of this activity have no relevant financial relationships.



  • Edith M. Williams, PhD, MS

    Associate Professor
    Department of Public Health Sciences
    College of Medicine
    Division of Rheumatology and Immunology
    Core Investigator
    MUSC Center for Health Disparities Research
    Medical University of South Carolina
    Charleston, South Carolina


    No relevant financial relationships

  • Michelle Petri, MD, MPH

    Professor of Medicine
    Hopkins Lupus Center
    Johns Hopkins University School of Medicine
    Baltimore, Maryland


    Participation by Dr Michelle Petri does not constitute or imply endorsement by the Johns Hopkins University or the Johns Hopkins Hospital and Health System.
    Grants for clinical research from: AstraZeneca Pharmaceuticals LP; Exagen Diagnostics, Inc.; GlaxoSmithKline; Janssen; Lilly USA, LLC; Thermo Fisher Scientific Inc.
    Advisor or consultant for: Alexion Pharmaceuticals, Inc.; Amgen, Inc.; AstraZeneca Pharmaceuticals LP; Aurinia Pharmaceuticals; Axdev; Boston Pharmaceuticals; Bristol Myers Squibb Company; Emergent BioSolutions; Gilead Sciences, Inc.; GlaxoSmithKline; Idorsia Pharmaceuticals Ltd; IQVIA; Janssen; Kezar Life Sciences; Lilly; Merck EMD Serono; Momenta Pharmaceuticals, Inc.; PPD Development; Sanofi; UCB Pharma, Inc.

  • Richard Furie, MD

    Division of Rheumatology
    Northwell Health
    The Marilyn and Barry Rubenstein Chair in Rheumatology
    Professor of Medicine
    Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
    Hempstead, New York


    Grants for clinical research from: AstraZeneca Pharmaceuticals LP; Aurinia Pharmaceuticals; Biogen; Genentech; GlaxoSmithKline; Lilly USA, LLC
    Advisor or consultant for: AstraZeneca Pharmaceuticals LP; Aurinia Pharmaceuticals; Biogen; Genentech; GlaxoSmithKline; Lilly USA, LLC
    Speaker or member of speakers bureau for: AstraZeneca Pharmaceuticals LP; Genentech


  • Karen Badal, MD, MPH

    Senior Medical Education Director, Medscape, LLC


    Disclosure: Karen Badal, MD, MPH, has disclosed no relevant financial relationships.

Compliance Reviewer

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Disclosure: Stephanie Corder, ND, RN, CHCP, has no relevant financial relationships.

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Systemic Lupus Erythematosus: Micro Lessons on the Future of Biologics

Authors: Edith M. Williams, PhD, MS; Michelle Petri, MD, MPH; Richard Furie, MDFaculty and Disclosures

CME Released: 2/23/2022

Valid for credit through: 2/23/2023, 11:59 PM EST


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Did you know that prednisone daily dosages above 6 mg increase the risk of future organ damage by 50% in patients with lupus?

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