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CME / CE

Current Perspectives in Bipolar Disorder and Depression

  • Authors: Joseph F. Goldberg, MD; Leslie Citrome, MD, MPH; Marlene P. Freeman, MD; Michael Morhous, DO; Gerard Sanacora, MD, PhD; Holly A. Swartz, MD; Michael E. Thase, MD
  • CME / CE Released: 12/22/2021
  • Valid for credit through: 12/22/2022
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  • Credits Available

    Physicians - maximum of 3.00 AMA PRA Category 1 Credit(s)™

    Nurses - 3.00 ANCC Contact Hour(s) (2.5 contact hours are in the area of pharmacology)

    You Are Eligible For

    • Letter of Completion

Target Audience and Goal Statement

This activity is intended for psychiatrists, primary care physicians (PCPs), obstetricians/gynecologists (Ob/Gyns), nurse practitioners (NPs), and physician assistants (PAs) involved in the care of patients with major depressive disorder (MDD), bipolar disorder (BD), or postpartum depression (PPD).

The goal of this activity is to improve clinicians' awareness of diagnosing BD and managing BD.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Clinical data for therapies studied for the management of BD
    • Factors that differentiate bipolar depression from unipolar depression
    • Clinical data on new and emerging treatments for the management of major depression
  • Have greater competence related to
    • Selection of appropriate therapies for the management of BD
    • Timely and accurate recognition of depressive disorders
    • Development of a treatment plan for the management of treatment-resistant depression (TRD)
    • Development of a treatment plan for BD when established therapies are ineffective or poorly tolerated
    • Identification of substance abuse in patients with a comorbid psychiatric disorder


Disclosures

As an organization accredited by the ACCME, Medscape, LLC requires everyone who is in a position to control the content of an education activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines "relevant financial relationships" as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner, that could create a conflict of interest.

Medscape, LLC encourages Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.


Chair/Faculty

  • Joseph F. Goldberg, MD

    Clinical Professor of Psychiatry 
    Icahn School of Medicine at Mount Sinai 
    New York, New York

    Disclosures

    Disclosure: Joseph F. Goldberg, MD, has disclosed the following relevant financial relationships: 
    Served as an advisor or consultant for: BioXcel; Jazz Pharmaceuticals, Inc.; Lundbeck, Inc.; Otsuka Pharmaceutical Co., Ltd.; Sage Pharmaceuticals; Sunovion Pharmaceuticals Inc. 
    Served as a speaker or a member of a speakers bureau for: AbbVie Inc.; Alkermes, Inc.; Sunovion Pharmaceuticals Inc.

Faculty

  • Leslie Citrome, MD, MPH

    Clinical Professor 
    Psychiatry and Behavioral Sciences 
    New York Medical College
    New York, New York

    Disclosures

    Disclosure: Leslie Citrome, MD, MPH, has disclosed the following relevant financial relationships: 
    Served as an advisor or consultant for: AbbVie/Allergan; Acadia; Adamas; Alkermes; Angelini; Astellas; Avanir; Axsome; BioXcel; Boehringer Ingelheim; Cadent Therapeutics; Eisai; Impel; Intra-Cellular Therapies; Janssen; Karuna; Lundbeck; Lyndra Therapeutics; Medavante-ProPhase; Merck; Neurocrine Biosciences, Inc.; Novartis; Noven; Otsuka; Ovid; Relmada; Reviva; Sage; Sunovion; Teva
    Served as a speaker or a member of a speakers bureau for: AbbVie/Allergan; Acadia; Alkermes; Angelini; Eisai; Intra-Cellular Therapies; Janssen; Lundbeck; NACCME; Neurocrine Biosciences, Inc.; Noven; Otsuka; Sage; Sunovion; Takeda; Teva

  • Marlene P. Freeman, MD

    Professor of Psychiatry, Harvard Medical School
    Associate Director, Center for Women's Mental Health
    Medical Director, CTNI
    Massachusetts General Hospital
    Boston, Massachusetts

    Disclosures

    Disclosure: Marlene P. Freeman, MD, has disclosed the following relevant financial relationships: 
    Served as an advisor or consultant for: Alkermes, Inc.; Aurobindo Pharma; AuroMedics Pharma; Janssen Pharmaceuticals; Novartis Pharmaceuticals Corporation; Otsuka Pharmaceutical Co., Ltd.; Sage Therapeutics; Sunovion Pharmaceuticals Inc.; Supernus Pharmaceuticals, Inc.; Teva Pharmaceuticals USA

  • Michael Morhous, DO

    Clinical Associate Professor
    Department of Psychiatry
    NYU Grossman School of Medicine
    New York, New York

    Disclosures

    Disclosure: Michael Morhous, DO, has disclosed no relevant financial relationships.

  • Gerard Sanacora, MD, PhD

    George D. Gross and Esther S. Gross 
    Professor of Psychiatry
    Yale University School of Medicine
    Director Yale Depression Research Program
    Co-Director Yale New Haven Hospital 
    Interventional Psychiatry Service
    New Haven, Connecticut 

    Disclosures

    Disclosure: Gerard Sanacora, MD, PhD, has disclosed the following relevant financial relationships: 
    Served as an advisor or consultant for: Allergan, Inc.; Axsome Therapeutics; Biohaven Pharmaceuticals; Bristol-Myers Squibb Company; Clexio Biosciences; EMA Wellness; Engrail Denovo Biopharma; Gilgamesh; Intra-Cellular Therapies, Inc.; Janssen Pharmaceuticals; Levo; Lundbeck, Inc.; Merck & Co., Inc.; Navitor Pharmaceuticals; Neurocrine Biosciences, Inc.; Novartis Pharmaceuticals Corporation; Noven Pharmaceuticals, Inc.; Perception Pharmaceuticals; Praxis; Sage Pharmaceuticals; Seelos Pharmaceuticals; XW LAbs
    Received grants for clinical research from: Janssen Pharmaceuticals; Merck & Co., Inc.
    Owns stock, stock options, or bonds from: Biohaven Pharmaceuticals

  • Holly A. Swartz, MD

    Professor of Psychiatry
    University of Pittsburgh School of Medicine
    Pittsburgh, Pennsylvania

    Disclosures

    Disclosure: Holly A. Swartz, MD, has disclosed the following relevant financial relationships: 
    Served as an advisor or consultant for: Intra-Cellular Therapies 
    Served as a speaker or a member of a speakers bureau for: Myriad Genetics
    Received grants for clinical research from: Myriad Genetics

  • Michael E. Thase, MD

    Current Challenges and Future Hope in the Management of Major Depression
    Professor, Department of Psychiatry
    University of Pennsylvania 
    Perelman School of Medicine
    Philadelphia, Pennsylvania

    Disclosures

    Disclosure: Michael E. Thase, MD, has disclosed the following relevant financial relationships: 
    Served as an advisor or consultant for: Acadia, Inc.; Akili, Inc.; Alkermes PLC; Allergan, Inc.; Axsome Therapeutics, Inc; BioHaven, Inc.; Bocemtium Consulting, S.L.; Boehringer Ingelheim International; CatalYm GmbH; Clexio Biosciences; Gerson Lehrman Group, Inc.; H. Lundbeck, A/S; Jazz Pharmaceuticals; Janssen; Johnson & Johnson; Merck & Company, Inc.; Otsuka Pharmaceutical Company, Ltd.; Pfizer, Inc.; Sage Pharmaceuticals; Seelos Pharmaceuticals; Sunovion Pharmaceuticals, Inc.; Takeda Pharmaceutical Company, Ltd.
    Received grants for clinical research from: Acadia, Inc.; Allergan, Inc.; AssureRx Health; Axsome Therapeutics Inc.; BioHaven, Inc.; Intracellular, Inc.; Johnson & Johnson; Otsuka Pharmaceutical Company, Ltd.; Patient-Centered Outcomes Research Institute (PCORI); Takeda Pharmaceutical Company, Ltd

Editor

  • Kathy Merlo

    Medical Education Director, Medscape, LLC

    Disclosures

    Disclosure: Kathy Merlo has disclosed no relevant financial relationships.

CME/Content Reviewer

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Disclosure: Stephanie Corder, ND, RN, CHCP, has disclosed no relevant financial relationships.

None of the nonfaculty planners for this educational activity have relevant financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, reselling, or distributing healthcare products used by or on patients.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.


Accreditation Statements



In support of improving patient care, Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 3.0 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Contact This Provider

    For Nurses

  • Awarded 3.0 contact hour(s) of continuing nursing education for RNs and APNs; 2.50 contact hours are in the area of pharmacology.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / CE

Current Perspectives in Bipolar Disorder and Depression

Authors: Joseph F. Goldberg, MD; Leslie Citrome, MD, MPH; Marlene P. Freeman, MD; Michael Morhous, DO; Gerard Sanacora, MD, PhD; Holly A. Swartz, MD; Michael E. Thase, MDFaculty and Disclosures

CME / CE Released: 12/22/2021

Valid for credit through: 12/22/2022

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Contents of This CME Activity

All sections of this activity are required for credit.

Expert Perspectives: Clinically Challenging Cases in Bipolar Disorder

Drs Citrome and Goldberg discuss the diagnosis and treatment of bipolar disorder.
Leslie Citrome, MD, MPH; Joseph F. Goldberg, MD​

Difficult to Treat ​Bipolar Disorder: A Look Into the Future of Therapeutics for Bipolar Disorder

Dr Swartz discusses emerging treatment options for bipolar disorder.
Holly A. Swartz, MD

Bipolar Depression: ​ A Review of Common Errors and Potential Solutions

Joseph F. Goldberg, MD​
Dr Goldberg discusses available treatment options for bipolar disorder.

Current Challenges and Future Hope in the Management of Major Depression

Dr Thase discusses emerging treatment options for major depression.
Michael E. Thase, MD

Treatment Resistance in Mood Disorders​: Challenges and Opportunities

Dr Sanacora discusses the management of difficult-to-treat depression.
Gerard Sanacora, MD, PhD

Family Matters: Case Examples of Care in Postpartum Depression​

Learn more about the recognition and treatment of postpartum depression.
Marlene P. Freeman, MD

The Dual Diagnosis Dilemma: Substance Use and Co-Occurring Mood Disorders​

Dr Morhous discusses the recognition of substance abuse in patients with a mood disorder.
Michael Morhous, DO
 

Pre-Assessment Survey