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Statin Therapy: Success Depends on Adherence

  • Authors: Joseph Saseen, PharmD, FNLA
  • CME / ABIM MOC / CE Released: 11/9/2021
  • Valid for credit through: 11/9/2022, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for cardiologists, primary care physicians, diabetologists, endocrinologists, nurses, pharmacists, and all clinicians caring for patients needing statin therapy.

The goal of this activity is to improve individualization of lipid therapy and adherence to statin use.

Upon completion of this activity, participants will:

  • Have increased knowledge related to
    • Selecting the most appropriate statin therapy for a given patient
    • Individualizing comprehensive treatment and follow up of patients receiving statin therapy
    • Providing patient education by the care team for improved initiation and/or adherence to statin therapy


As an organization accredited by the ACCME, Medscape, LLC requires everyone who is in a position to control the content of an education activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines "relevant financial relationships" as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner, that could create a conflict of interest.

Medscape, LLC encourages Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.


  • Joseph Saseen, PharmD, FNLA

    Professor and Associate Dean for Clinical Affairs
    Skaggs School of Pharmacy and Pharmaceutical Sciences
    Professor of Family Medicine
    University of Colorado Anschutz Medical Campus
    Aurora, Colorado
    President, National Lipid Association


    Disclosure: Joseph Saseen, PharmD, FNLA, has no relevant financial relationships.  


  • Joy P. Marko, MS, APN-C, CCMEP

    Senior Medical Education Director, Medscape, LLC 


    Disclosure: Joy P. Marko, MS, APN-C, CCMEP, has disclosed no relevant financial relationships.

CME, CE Reviewer/Nurse Planner

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Disclosure: Stephanie Corder, ND, RN, CHCP, has disclosed no relevant financial relationships.

None of the nonfaculty planners for this educational activity have relevant financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, reselling, or distributing healthcare products used by or on patients.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.

Accreditation Statements


Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


This activity was planned by and for the healthcare team, and learners will receive 0.25 Interprofessional Continuing Education (IPCE) credit for learning and change.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.25 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

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    For Nurses

  • Awarded 0.25 contact hour(s) of continuing nursing education for RNs and APNs; 0.25 contact hours are in the area of pharmacology.

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    For Pharmacists

  • Medscape, LLC designates this continuing education activity for 0.25 contact hour(s) (0.025 CEUs) (Universal Activity Number JA0007105-0000-21-288-H01-P).

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This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

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Statin Therapy: Success Depends on Adherence

Authors: Joseph Saseen, PharmD, FNLAFaculty and Disclosures

CME / ABIM MOC / CE Released: 11/9/2021

Valid for credit through: 11/9/2022, 11:59 PM EST



Clinical information from medical record:
Name:  Paula S
Age: 65
History: Hypertension x 15 years; hyperlipidemia x 10 years; depression x 20 years; obesity
Family history: Father; myocardial infarction at age 49 years
Clinical data:

  • BP = 125/75 mmHg
  • Heart rate = 74 bpm
  • BMI = 33 kg/m2

Test results:

  • Total cholesterol = 205 mg/dL
  • LDL-C = 130 mg/dL; HDL-C = 35 mg/dL; TG = 200 mg/dL
  • A1c = 6.1%

Current Rx:
Amlodipine/olmesartan 5/20 mg once daily; citalopram 10 mg once daily

Clinical Vignette, Part 1 

Clinician: Good morning! So nice to meet you, Paula. I’m Dr. Booher.
Patient: [says respectfully] Hello, dear. That’s a lovely haircut. (compliments her in some way, ie, hair, earrings, necklace, etc)
Clinician: Why, thank you. Now if I understand correctly, you were a patient of Dr Singh.
Patient: Yes. Yes, I was. We had a good run…her and I. I’ll miss her. But I suppose you can’t fault a person for retiring.
Clinician: [smiles] No, I suppose not. [pretends to whisper] But I miss her too.
So, let’s take a look, here. [glances at file on desk and short pause]. The office left a note that you’re running out of your medications. Is that correct?
Patient: Yes, that’s correct. I’ll run out of the blood pressure pills real soon. I take one of those every day.
Clinician: All right. Are you still taking the citalopram for depression?
Patient: Yes, but I’ve got enough refills on those.
Clinician: And what about your cholesterol medication?
Patient: Well, I haven’t really been taking that one. My neighbor and I got to talking -- she’s a very smart lady -- and she was telling me that those statins can be bad for your blood sugar … can actually cause diabetes. Dr Singh once told me that I have pre-diabetes and [shakes head “no”] mm-mm…I don’t want to mess with that. My father had diabetes. It was tough on him. He had a heart attack when he was only 49.

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