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How Much Blood Pressure Lowering Does it Take to Reduce CV Risk? The Answer May Surprise You

  • Authors: Debbie L. Cohen, MD; Kazem Rahimi, FRCP, DM, MSc, FESC
  • CME / ABIM MOC Released: 9/17/2021
  • Valid for credit through: 9/17/2022, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for cardiologists, primary care physicians, and nephrologists.

The goal of this activity is to review results of a meta-analysis assessing the degree of blood pressure lowering and its impact on CV outcomes.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Results of a recent meta-analysis looking at 51 large-scale, randomized, antihypertensive drug trials that looked at degree of blood pressure lowering
    • Effect on cardiovascular outcomes of blood pressure reduction of approximately 5 mm Hg


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  • Debbie L. Cohen, MD

    Professor of Medicine
    Director of Clinical Hypertension Programs
    Co-Director of Neuroendocrine Tumor Program
    Hospital of the University of Pennsylvania
    Philadelphia, Pennsylvania, United States


    Disclosure: Debbie L. Cohen, MD, has the following relevant financial relationships:
    Advisor or consultant for: Medtronic
    Grants for clinical research from: Medtronic

  • Kazem Rahimi, FRCP, DM, MSc, FESC

    Professor of Cardiovascular Medicine and Population Health
    Director, Deep Medicine Programme, Oxford Martin School
    University of Oxford
    Honorary Consultant Cardiologist, Oxford University Hospitals NHS Trust
    Nuffield Department of Women’s and Reproductive Health
    Oxford, United Kingdom


    Disclosure: Kazem Rahimi, FRCP, DM, MSc, FESC, has no relevant financial relationships.


  • George Boutsalis, PhD

    Director, Content Development, Medscape, LLC


    Disclosure: George Boutsalis, PhD, has disclosed no relevant financial relationships

CME Reviewer

  • Esther Nyarko, PharmD

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Disclosure: Esther Nyarko, PharmD, has disclosed no relevant financial relationships.

None of the nonfaculty planners for this educational activity have relevant financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, reselling, or distributing healthcare products used by or on patients.

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    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

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How Much Blood Pressure Lowering Does it Take to Reduce CV Risk? The Answer May Surprise You

Authors: Debbie L. Cohen, MD; Kazem Rahimi, FRCP, DM, MSc, FESCFaculty and Disclosures

CME / ABIM MOC Released: 9/17/2021

Valid for credit through: 9/17/2022, 11:59 PM EST


Educational Impact Challenge

The goal of this activity is to review results of a meta-analysis assessing the degree of blood pressure lowering and its impact on CV outcomes.

Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.

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