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CPD

Novel Dual GIP/GLP-1 Receptor Agonists: Appraising First Major Clinical Data

  • Authors: Stefano Del Prato, MD, PhD​; Juan Pablo Frías, MD; Francesco Giorgino, MD, PhD​; Carol Wysham, MD
  • CPD Released: 7/15/2021
  • THIS ACTIVITY HAS EXPIRED
  • Valid for credit through: 7/15/2022
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Target Audience and Goal Statement

This activity is intended for diabetologists/endocrinologists and primary care providers (PCPs). 

The goal of this activity is to increase awareness of novel dual incretin-based therapies and first clinical data from the SURPASS phase 3 program with tirzepatide as presented at the American Diabetes Association (ADA) virtual congress 2021.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Antidiabetic and weight loss concept of novel dual incretin-based therapies  
    • Evidence for the effectiveness and safety of dual glucose-dependent insulinotropic peptide (GIP)/ glucagon-like peptide-1 receptor agonists (GLP-1 RAs) from early clinical trials


Disclosures

WebMD Global requires each individual who is in a position to control the content of one of its educational activities to disclose any relevant financial relationships occurring within the past 12 months that could create a conflict of interest.


Faculty

  • Stefano Del Prato, MD, PhD

    Professor of Endocrinology and Metabolism​
    Chief, Section of Diabetes and Metabolic Diseases​
    University of Pisa​
    Pisa, Italy

    Disclosures

    Disclosure: Stefano Del Prato, MD, PhD, has the following relevant financial relationships:
    Advisor or consultant for: Applied Therapeutics; AstraZeneca; Boehringer Ingelheim; Eli Lilly and Co; Merck & Co.; Novartis Pharmaceuticals; Novo Nordisk; Sanofi
    Speaker or a member of a speakers bureau for: AstraZeneca; Boehringer Ingelheim; Eli Lilly and Co; Merck & Co.; Novartis Pharmaceuticals; Novo Nordisk; Sanofi; Takeda Pharmaceuticals
    Grants for clinical research from: AstraZeneca; Boehringer Ingelheim

  • Juan Pablo Frías, MD

    Medical Director and Principal Investigator ​
    National Research Institute​
    Los Angeles, California, United States
    Assistant Clinical Professor of Medicine​
    Division of Endocrinology​
    University of California San Diego​
    San Diego, California, United States

    Disclosures

    Disclosure: Juan Pablo Frías, MD, has the following relevant financial relationships:
    Advisor or consultant for: Akero; Altimmune; Axcella Health; Boehringer Ingelheim; Carmot; Coherus Therapeutics; Echosens; 89bio; Eli Lilly; Gilead; Intercept; Merck; Novo Nordisk; Pfizer; Sanofi
    Speaker or a member of a speakers bureau for: Eli Lilly, Merck, Sanofi
    Grants for clinical research from: Akero; AbbVie; AstraZeneca; Boehringer Ingelheim; BMS; Eli Lilly; Intercept; Janssen; Madrigal; Metacrine; Merck; NorthSea Therapeutics; Novartis; Novo Nordisk; Oramed; Pfizer; Poxil; Sanofi; Theracos

  • Francesco Giorgino, MD, PhD

    Professor of Endocrinology and Metabolism​
    Chief, Division of Endocrinology​
    University Hospital Policlinico Consorziale​
    University of Bari Aldo Moro​
    Bari, Italy​

    Disclosures

    Disclosure: Francesco Giorgino, MD, PhD, has the following relevant financial relationships:
    Advisor or consultant for: AstraZeneca; Boehringer-Ingelheim; Diabetes Care; Eli Lilly; NovoNordisk; Roche
    Speaker or a member of a speakers bureau for: AstraZeneca; Boehringer-Ingelheim; Diabetes Care; Eli Lilly; NovoNordisk; Roche

  • Carol Wysham, MD

    Clinical Professor of Medicine​
    University of Washington​
    School of Medicine​
    Rockwood/MultiCare Center for Diabetes and Endocrinology​
    Spokane, Washington, United States

    Disclosures

    Disclosure: Carol Wysham, MD, has the following relevant financial relationships:
    Advisor or consultant for: Abbott; Novo Nordisk; Sanofi
    Speaker or a member of a speakers bureau for: AstraZeneca; Boehringher Ingelheim; Eli Lilly; Janssen; Novo Nordisk; Sanofi
    Grants for clinical research from: Abbott; Gilead; Corcept; Novo Nordisk; Milan; Eli Lilly

Editors

  • Rita Moreira Da Silva, PhD, MA, PharmD

    Medical Education Director, WebMD Global, LLC

    Disclosures

    Disclosure: Rita Moreira Da Silva, PhD, MA, PharmD, has disclosed no relevant financial relationships.

  • Marcel Meijer, PhD

    Medical Education Director, WebMD Global, LLC

    Disclosures

    Disclosure: Marcel Meijer, PhD, has disclosed no relevant financial relationships.

Content Reviewer

  • Robert Morris, PharmD

    Associate Director, Accreditation and Compliance, Medscape, LLC

    Disclosures

    Disclosure: Robert Morris, PharmD, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: ViiV Healthcare
    Owns stock, stock options, or bonds from: GlaxoSmithKline

None of the nonfaculty planners for this educational activity have relevant financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, reselling, or distributing healthcare products used by or on patients.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.


Accreditation Statements

    For Physicians

  • The Faculty of Pharmaceutical Medicine of the Royal Colleges of Physicians of the United Kingdom (FPM) has reviewed and approved the content of this educational activity and allocated it 0.75 continuing professional development credits (CPD).

    Contact WebMD Global

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information about your eligibility to claim credit, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent participating in the activity. To successfully earn credit, participants must complete the activity online during the credit eligibility period that is noted on the title page.

Follow these steps to claim a credit certificate for completing this activity:

  1. Read the information provided on the title page regarding the target audience, learning objectives, and author disclosures, read and study the activity content and then complete the post-test questions. If you earn a passing score on the post-test and we have determined based on your registration profile that you may be eligible to claim CPD credit for completing this activity, we will issue you a CPD credit certificate.
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CPD

Novel Dual GIP/GLP-1 Receptor Agonists: Appraising First Major Clinical Data

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Mechanism of Action and Concept of Novel Dual Incretin-based Therapies

 

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