This activity is intended for oncologists, pathologists, and surgeons.
The goal of this activity is to improve clinicians' ability to manage patients with recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC).
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CME / ABIM MOC Released: 1/25/2021
Valid for credit through: 1/25/2022, 11:59 PM EST
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The following cases are modeled on the interactive grand rounds approach. The questions within the activity are designed to test your current knowledge. After each question, you will be able to see whether you answered correctly and read evidence-based information that supports the most appropriate answer choice. The questions are designed to challenge you; you will not be penalized for answering the questions incorrectly. At the end of the activity, there will be a short post-test assessment based on the material presented.
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Tabitha is a 44-year-old pediatrician who presented with a T4N0 right lateral tongue lesion. She underwent primary surgery. Surgical pathology showed a human papilloma virus (HPV)-negative squamous cell carcinoma (SCC) with positive surgical margins, invasion of the mandible, and perineural invasion. She received adjuvant therapy with concurrent radiation therapy and cisplatin.
She now presents 7 months after completion of adjuvant therapy with sharp pain while eating and occasional dysphagia with solid foods. She denies pain while swallowing or any other new symptoms. She continues to experience dry mouth from her radiation therapy. She tells you she recently lost 10 lb, but she started taking an aerobics class at the gym with her best friend and assumed that was the cause of her weight loss. Tabitha's initial exam and imaging are summarized in Table 1.
Table 1. Summary of Tabitha's Initial Workup
Demographics |
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Personal and family medical history |
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Physical exam |
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Imaging |
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BMI = body mass index; BP = blood pressure; CT = computed tomography; ECOG = Eastern Cooperative Oncology Group; HR = heart rate; PET = positron emission tomography; PS = performance status; RR = respiration rate.
Tabitha was evaluated by a head and neck multidisciplinary team that included otolaryngology, radiation oncology, and medical oncology.