Anker SD, Comin Colet J, Filippatos G, et al; FAIR-HF Trial Investigators. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med. 2009;361:2436-2448.
Besarab A, Bolton WK, Browne JK, et al. The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med. 1998;339:584-590.
Drüeke TB, Locatelli F, Clyne N, et al; CREATE Investigators. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med. 2006;355:2071-2084.
Fishbane S, Pollack S, Feldman HI, et al. Iron indices in chronic kidney disease in the National Health and Nutritional Examination Survey 1988-2004. Clin J Am Soc Nephrol. 2009;4:57-61.
Ganz T, Nemeth E. The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders. Hematology Am Soc Hematol Educ Program. 2011;2011:538-542.
Goodnough LT. Iron deficiency syndromes and iron-restricted erythropoiesis (CME). Transfusion. 2012;52:1584-1592.
Kalantar-Zadeh K, Streja E, Miller JE, et al. Intravenous iron versus erythropoiesis-stimulating agents: friends or foes in treating chronic kidney disease anemia? Adv Chronic Kidney Dis. 2009;16:143-151.
Kidney Disease Improving Global Outcomes (KDIGO) Anemia Work Group, . KDIGO clinical practice guideline for anemia in chronic kidney disease. Kidney Int Suppl. 2012;2:279-335.
Locatelli F, Bárány P, Covic A, et al; ERA-EDTA ERBP Advisory Board. Kidney Disease: Improving Global Outcomes guidelines on anaemia management in chronic kidney disease: a European Renal Best Practice position statement. Nephrol Dial Transplant. 2013;28:1346-1359.
Macdougall IC, Bock A, Carrera F, et al; FIND-CKD Study Investigators. The FIND-CKD study--a randomized controlled trial of intravenous iron versus oral iron in non-dialysis chronic kidney disease patients: background and rationale. Nephrol Dial Transplant. 2014;29:843-850.
Macdougall IC, Bock AH, Carrera F, et al; FIND-CKD Study Investigators. FIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia. Nephrol Dial Transplant. 2014;29:2075-2084.
Macdougall IC, White C, Anker SD, et al; PIVOTAL Investigators and Committees. Intravenous iron in patients undergoing maintenance hemodialysis. N Engl J Med. 2019;380:447-458.
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Moderator

Austin Stack, MD, MBBCh, MSc, FRCPI, FASN

Professor of Medicine
School of Medicine
University of Limerick
Limerick, Ireland

Disclosures

Disclosure: Austin Stack, MD, MBBCH, MSc, FRCPI, FASN, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Astellas Pharma, Inc.; AstraZeneca Pharmaceuticals LP; Menarini Group; Vifor Pharma
Served as a speaker or a member of a speakers bureau for: Astellas Pharma, Inc.; Vifor Pharma
Received grants for clinical research from: Menarini Group; Vifor Pharma

Panelists

Aleix Cases, MD, PhD

Senior Consultant in Nephrology
Assistant Professor of Medicine
Hospital Clinic
Barcelona, Spain

Disclosures

Disclosure: Aleix Cases, MD, PhD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Astellas Pharma, Inc.; AstraZeneca Pharmaceuticals LP; Boehringer Ingelheim Pharmaceuticals, Inc.; GlaxoSmithKline; Novo Nordisk; Vifor Pharma
Served as a speaker or a member of a speakers bureau for: Amgen Inc.; Astellas Pharma, Inc.; Bayer AG; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; Novo Nordisk
Received grants for clinical research from: AB-Biotics, S.A.; Vifor Pharma

Martin de Borst, MD, PhD

Consultant Nephrologist
Adjunct Professor of Medicine
University Medical Center
Groningen, the Netherlands

Disclosures

Disclosure: Martin de Borst, MD, PhD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Kyowa Kirin Co., Ltd.; Pharmacosmos A/S; Sanofi Genzyme; Vifor Pharma
Served as a speaker or a member of a speakers bureau for: Kyowa Kirin Co., Ltd.; Sanofi Genzyme; Vifor Pharma
Received grants for clinical research from: Sanofi Genzyme; Vifor Pharma

Editor

George Boutsalis, PhD

Senior Medical Education Director
Medscape, LLC

Disclosures

Disclosure: George Boutsalis, PhD, has disclosed no relevant financial relationships.

Content Reviewer

Robert Morris, PharmD

Associate Director, Accreditation and Compliance, Medscape, LLC

Disclosures

Disclosure: Robert Morris, PharmD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: ViiV Healthcare
Owns stock, stock options, or bonds from: GlaxoSmithKline

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.

CPD

Iron Deficiency Anemia in Chronic Kidney Disease: Discussing Patient Cases

Authors: Austin Stack, MD, MBBCh, MSc, FRCPI, FASN; Aleix Cases, MD, PhD; Martin de Borst, MD, PhD
CPD Released: 1/21/2021
THIS ACTIVITY HAS EXPIRED FOR CREDIT
Valid for credit through: 1/21/2022, 11:59 PM EST

Start Activity

Target Audience and Goal Statement

This educational activity is intended for an international audience of non-US nephrologists, primary care physicians, and cardiologists

The goal of this activity is to discuss the diagnosis, monitoring, and treatment of iron deficiency anemia in patients with chronic kidney disease (CKD).

Upon completion of this activity, participants will:

Have increased knowledge regarding the
- Iron deficiency anemia in the setting of CKD with or without heart failure
- Guideline recommendations for diagnosis, monitoring, and treatment algorithm
Have greater competence related to
- Making individualized treatment decisions

Disclosures

Moderator

Austin Stack, MD, MBBCh, MSc, FRCPI, FASN

Professor of Medicine
School of Medicine
University of Limerick
Limerick, Ireland

Disclosures

Disclosure: Austin Stack, MD, MBBCH, MSc, FRCPI, FASN, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Astellas Pharma, Inc.; AstraZeneca Pharmaceuticals LP; Menarini Group; Vifor Pharma
Served as a speaker or a member of a speakers bureau for: Astellas Pharma, Inc.; Vifor Pharma
Received grants for clinical research from: Menarini Group; Vifor Pharma

Panelists

Aleix Cases, MD, PhD

Senior Consultant in Nephrology
Assistant Professor of Medicine
Hospital Clinic
Barcelona, Spain

Disclosures

Disclosure: Aleix Cases, MD, PhD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Astellas Pharma, Inc.; AstraZeneca Pharmaceuticals LP; Boehringer Ingelheim Pharmaceuticals, Inc.; GlaxoSmithKline; Novo Nordisk; Vifor Pharma
Served as a speaker or a member of a speakers bureau for: Amgen Inc.; Astellas Pharma, Inc.; Bayer AG; Boehringer Ingelheim Pharmaceuticals, Inc.; Bristol-Myers Squibb Company; Novo Nordisk
Received grants for clinical research from: AB-Biotics, S.A.; Vifor Pharma

Martin de Borst, MD, PhD

Consultant Nephrologist
Adjunct Professor of Medicine
University Medical Center
Groningen, the Netherlands

Disclosures

Disclosure: Martin de Borst, MD, PhD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Kyowa Kirin Co., Ltd.; Pharmacosmos A/S; Sanofi Genzyme; Vifor Pharma
Served as a speaker or a member of a speakers bureau for: Kyowa Kirin Co., Ltd.; Sanofi Genzyme; Vifor Pharma
Received grants for clinical research from: Sanofi Genzyme; Vifor Pharma

Editor

George Boutsalis, PhD

Senior Medical Education Director
Medscape, LLC

Disclosures

Disclosure: George Boutsalis, PhD, has disclosed no relevant financial relationships.

Content Reviewer

Robert Morris, PharmD

Associate Director, Accreditation and Compliance, Medscape, LLC

Disclosures

Disclosure: Robert Morris, PharmD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: ViiV Healthcare
Owns stock, stock options, or bonds from: GlaxoSmithKline

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.

Accreditation Statements

For Physicians

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From Medscape Education

CPD

Iron Deficiency Anemia in Chronic Kidney Disease: Discussing Patient Cases

Authors: Austin Stack, MD, MBBCh, MSc, FRCPI, FASN; Aleix Cases, MD, PhD; Martin de Borst, MD, PhDFaculty and Disclosures

THIS ACTIVITY HAS EXPIRED FOR CREDIT

CPD Released: 1/21/2021

Valid for credit through: 1/21/2022, 11:59 PM EST

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Disclaimer

The educational activity presented above may involve simulated, case-based scenarios. The patients depicted in these scenarios are fictitious and no association with any actual patient, whether living or deceased, is intended or should be inferred. The material presented here does not necessarily reflect the views of Medscape, LLC, or any individuals or commercial entities that support companies that support educational programming on medscape.org. These materials may include discussion of therapeutic products that have not been authorized by the European Medicines Agency for use in Europe, off-label uses of authorized products, or data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal. Readers should verify all information and data before treating patients or employing any therapies described in this or any educational activity. A qualified healthcare professional should be consulted before using any therapeutic product discussed herein.

References

Faculty and Disclosures

Moderator

Austin Stack, MD, MBBCh, MSc, FRCPI, FASN​

Panelists

Aleix Cases, MD, PhD

Martin de Borst, MD, PhD​

Editor

George Boutsalis, PhD

Content Reviewer

Robert Morris, PharmD

Peer Reviewer

CPD

Iron Deficiency Anemia in Chronic Kidney Disease: Discussing Patient Cases

Target Audience and Goal Statement

Disclosures

Moderator

Austin Stack, MD, MBBCh, MSc, FRCPI, FASN​

Panelists

Aleix Cases, MD, PhD

Martin de Borst, MD, PhD​

Editor

George Boutsalis, PhD

Content Reviewer

Robert Morris, PharmD

Peer Reviewer

Accreditation Statements

For Physicians

Instructions for Participation and Credit

Iron Deficiency Anemia in Chronic Kidney Disease: Discussing Patient Cases

Practice Assessment

Austin Stack, MD, MBBCh, MSc, FRCPI, FASN

Martin de Borst, MD, PhD

Austin Stack, MD, MBBCh, MSc, FRCPI, FASN

Martin de Borst, MD, PhD