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Patient Selection for Aspirin Therapy: Implications for Primary Care

  • Authors: Charles P. Vega, MD; Michael Blaha, MD, MPH
  • CME / ABIM MOC / CE Released: 10/26/2020
  • Valid for credit through: 10/26/2021, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for primary care clinicians, cardiologists, diabetologists & endocrinologists, nurses and other clinicians who care for individuals with cardiovascular disease.

The goal of this activity is to guide clinicians on the role of aspirin in primary prevention of cardiovascular disease and how they can identify the patients who may benefit from it.

Upon completion of this activity, participants will:

  • Have greater competence related to
    • Patient selection for aspirin therapy in the setting of primary prevention
    • Appropriate use of aspirin therapy for cardioprevention in the setting of primary prevention


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Medscape, LLC encourages Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.


  • Charles P. Vega, MD

    Health Sciences Clinical Professor of Family Medicine
    University of California
    Irvine School of Medicine
    Irvine, California


    Disclosure: Charles P. Vega, MD, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: Glaxo Smith Kline

  • Michael Blaha, MD, MPH

    Professor of Medicine
    Director of Clinical Research
    Ciccarone Center for the Prevention of Cardiovascular Disease
    Johns Hopkins University
    Baltimore, Maryland


    Disclosure: Michael Blaha, MD, MPH, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: Amgen; Akcea; Bayer; Novartis; Kowa; Novo Nordisk; Regeneron; Sanofi; 89Bio
    Received grants for clinical research from: Aetna; Amgen


  • Lih-Fan Chang, MD, MPH

    Medical Education Director, Medscape, LLC


    Disclosure: Lih-Fan Chang, MD, MPH, has disclosed no relevant financial relationships.

  • Gillian Griffith, BA (Mod), MA

    Medical Education Director, WebMD Global, LLC


    Disclosure: Gillian Griffith, BA (Mod), MA, has disclosed no relevant financial relationships.

CME, CE Reviewer/Nurse Planner

  • Stephanie Corder, ND, RN, CHCP

    Associate Director, Accreditation and Compliance, Medscape, LLC


    Disclosure: Stephanie Corder, ND, RN, CHCP, has disclosed no relevant financial relationships.

Medscape, LLC staff have disclosed that they have no relevant financial relationships.

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Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.25 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

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    For Nurses

  • Awarded 0.25 contact hour(s) of continuing nursing education for RNs and APNs; 0.25 contact hours are in the area of pharmacology.

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This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

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Patient Selection for Aspirin Therapy: Implications for Primary Care

Authors: Charles P. Vega, MD; Michael Blaha, MD, MPHFaculty and Disclosures

CME / ABIM MOC / CE Released: 10/26/2020

Valid for credit through: 10/26/2021, 11:59 PM EST


ABI = ankle-brachial index
ACC = American College of Cardiology
AHA = American Heart Association
ASCVD = atherosclerotic cardiovascular disease
CAC = coronary artery calcium
COE = class of recommendation
Crl = credible interval variables
CT = computed tomography
CV = cardiovascular
CVD = cardiovascular disease
EBCT = electron-beam computed tomography
GI = gastrointestinal
ICD-9 = International Classification of Diseases, Ninth Revision
ICD-10 = International Classification of Diseases, Tenth Revision
IMT = intima-media thickness
LDL-C = low density lipoprotein cholesterol
LOE = level of evidence
Lp(a) = lipoprotein (a)
MESA = Multi-Ethnic Study of Atherosclerosis
MI = myocardial infarction
NHS = National Health Service
NNH = number needed to harm
NNH5 = number needed to harm at 5 years
NNT5 = number needed to treat at 5 years
PCE = pooled cohort equation
RCT = randomized controlled trial
RR = rate ratio
RRI = relative risk increase
RRR = relative risk reduction
SVE = serious vascular event
TIA = transient ischemic attack
UA = unstable angina

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