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Identifying and Managing Hypophosphatemia Associated With IV Iron Treatment

  • Authors: Myles Wolf, MD, MMSc; Jason Ken Hou, MD, MS; and Yelena Ginzburg, MD
  • CME / ABIM MOC Released: 12/13/2019
  • Valid for credit through: 12/13/2020
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Target Audience and Goal Statement

This activity is intended for gastroenterologists, hematologists, and primary care physicians.

The goal of this activity is to improve clinicians’ awareness and knowledge about screening for and managing hypophosphatemia associated with intravenous (IV) iron treatment.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Need to screen patients on IV iron treatment for hypophosphatemia
    • Considerations for selection of IV iron therapy in patients with iron deficiency anemia
  • Have greater competence related to
    • Management of IV iron-induced hypophosphatemia in practice


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Medscape, LLC, encourages Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.


  • Myles Wolf, MD, MMSc

    Charles Johnson, MD, Professor of Medicine
    Chief of Nephrology
    Department of Medicine
    Duke University School of Medicine
    Durham, North Carolina


    Disclosure: Myles Wolf, MD, MMSc, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: Akebia Therapeutics; AMAG Pharmaceuticals; Amgen Inc.; Ardelyx; DiaSorin; Pharmacosmos


  • Yelena Ginzburg, MD

    Associate Professor
    Division of Hematology and Oncology
    Icahn School of Medicine at Mount Sinai/Tisch Cancer Institute
    New York, New York


    Disclosure: Yelena Ginzburg, MD, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: Ionis Pharmaceuticals; La Jolla Pharmaceutical Company; Protagonist Therapeutics

  • Jason Ken Hou, MD, MS

    Associate Professor
    Medicine and Gastroenterology
    GI & Hepatology Fellowship Program
    Baylor College of Medicine
    Houston, Texas


    Disclosure: Jason Ken Hou, MD, MS, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: AbbVie; Janssen Pharmaceutica; Pfizer Inc.
    Served as a speaker or a member of a speakers bureau for: AbbVie; Janssen Pharmaceutica; Pfizer Inc.
    Received grants for clinical research from: AbbVie; Boehringer Ingelheim Pharm Inc.; Celgene Corporation; Janssen Pharmaceutica; Pfizer Inc.; Redhill Biopharma Ltd.; Shield Therapeutics American Regent


  • Rod Smith, MS

    Medical Education Director, Medscape, LLC


    Disclosure: Rod Smith, MS, has disclosed no relevant financial relationships.

  • Heather Lewin, MAT

    Senior Scientific Content Manager, Medscape, LLC


    Disclosure: Heather Lewin, MAT, has disclosed no relevant financial relationships.

CME Reviewer

  • Cindy Tryniszewski, MSN, RN, FAEN

    Senior Director, Content Development, Medscape, LLC


    Disclosure: Cindy Tryniszewski, MSN, RN, FAEN, has disclosed no relevant financial relationships.

Medscape, LLC staff have disclosed that they have no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.

Accreditation Statements


In support of improving patient care, Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

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This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

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Identifying and Managing Hypophosphatemia Associated With IV Iron Treatment

Authors: Myles Wolf, MD, MMSc; Jason Ken Hou, MD, MS; and Yelena Ginzburg, MDFaculty and Disclosures

CME / ABIM MOC Released: 12/13/2019

Valid for credit through: 12/13/2020



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