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CME / ABIM MOC / CE

Amyloidosis in Cardiology Practice: A Race Against Time

  • Authors: Mathew Maurer, MD; Jose Nativi-Nicolau, MD; Ronald M. Witteles, MD
  • CME / ABIM MOC / CE Released: 3/28/2019
  • THIS ACTIVITY HAS EXPIRED FOR CREDIT
  • Valid for credit through: 3/28/2020, 11:59 PM EST
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Target Audience and Goal Statement

This activity is intended for cardiologists, neurologists, hematology and oncology specialists, and nurses.

The goal of this activity is to improve the recognition, diagnosis, and management of cardiac amyloidosis.

Upon completion of this activity, participants will:

  • Have increased knowledge regarding the
    • Clinical signs and symptoms of amyloidosis
    • Latest clinical data on treatment of hereditary transthyretin-related amyloidosis
  • Have greater competence related to
    • Patient assessment to improve early diagnosis of amyloidosis


Disclosures

As an organization accredited by the ACCME, Medscape, LLC, requires everyone who is in a position to control the content of an education activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines "relevant financial relationships" as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner, that could create a conflict of interest.

Medscape, LLC, encourages Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.


Moderator

  • Mathew Maurer, MD

    Arnold and Arlene Goldstein Professor of Cardiology
    Department of Medicine Cardiology
    Columbia University Medical Center
    New York, New York

    Disclosures

    Disclosure: Mathew Maurer, MD, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: Akcea Therapeutics; Amylon Therapeutics; Ionis Pharmaceutcials; Pfizer Inc.

Panelists

  • Jose Nativi-Nicolau, MD

    Assistant Professor
    University of Utah
    Salt Lake City, Utah

    Disclosures

    Disclosure: Jose Nativi-Nicolau, MD, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: Akcea Therapeutics; Alnylam Pharmaceuticals, Inc.; Pfizer Inc.
    Received grants for clinical research from: Akcea Therapeutics; Eidos Therapeutics; Pfizer Inc.

  • Ronald M. Witteles, MD

    Associate Professor of Cardiovascular Medicine
    Co-Director
    Stanford Amyloid Center
    Stanford University School of Medicine
    Stanford, California

    Disclosures

    Disclosure: Ronald M. Witteles, MD, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: Alnylam Pharmaceuticals, Inc.; Pfizer Inc.
    Received grants for clinical research from: Eidos Therapeutics; Pfizer Inc.

Editors

  • Joy P. Marko, MS, APN-C, CCMEP

    Scientific Director, Medscape, LLC

    Disclosures

    Disclosure: Joy P. Marko, MS, APN-C, CCMEP, has disclosed no relevant financial relationships.

  • Kalanethee Paul-Pletzer, PhD

    Scientific Director, Medscape, LLC

    Disclosures

    Disclosure: Kalanethee Paul-Pletzer, PhD, has disclosed no relevant financial relationships.

Nurse Planner

  • Amy Bernard, MS, BSN, RN-BC, CHCP

    Lead Nurse Planner, Medscape, LLC

    Disclosures

    Disclosure: Amy Bernard, MS, BSN, RN-BC, CHCP, has disclosed no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Abbott Laboratories; Medtronic, Inc.


Accreditation Statements

Medscape

Interprofessional Continuing Education

In support of improving patient care, Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Medscape, LLC staff have disclosed that they have no relevant financial relationships.

    Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.50 MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Aggregate participant data will be shared with commercial supporters of this activity.

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    For Nurses

  • Awarded 0.50 contact hour(s) of continuing nursing education for RNs and APNs; 0.25 contact hours are in the area of pharmacology.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / ABIM MOC / CE

Amyloidosis in Cardiology Practice: A Race Against Time

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Clinical Burden of Delayed Diagnosis and Impact on Mortality: What Happens If the Patient Is Misdiagnosed?

 

  • Clinical Burden of Delayed Diagnosis and Impact on Mortality: What Happens If the Patient Is Misdiagnosed?

  • Slide 1.

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  • Delayed Diagnosis: Consequences [12,13]

    • Death is the most devastating effect of a late diagnosis, especially in patients with AL amyloidosis
    • Delayed diagnosis increases disease burden as multiple organs are affected

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  • Staging of AL Amyloidosis and Prognosis [14]

    • Patients with elevated biomarkers and free light-chain difference have the worst outcomes

  • Slide 3.

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  • Cardiac AL Amyloidosis: A Race Against Time

    • Ruling in/out AL amyloidosis is a priority in suspected CA

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  • Diagnostic Algorithm [15]

    • AL amyloidosis can be ruled in/out with free light-chain assay
    • The assay is available in all laboratories

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