Airas L, Kaaja R. Pregnancy and multiple sclerosis. Obstet Med. 2012;5(3):94-97.
National Multiple Sclerosis Society website. Who gets MS? (Epidemiology). https://www.nationalmssociety.org/What-is-MS/Who-Gets-MS. Accessed August 9, 2018.
Coyle PK. Management of women with multiple sclerosis through pregnancy and after childbirth. Ther Adv Neurol Disord. 2016;9:198-210.
Teter B, Kavak KS, Kolb C, Coyle PK, Guttman BW. Parity associated with long-term disease progression in women with multiple sclerosis. J Mult Scler. 2014;1:101.
National Multiple Sclerosis website. Primary progressive multiple sclerosis: overview. https://www.nationalmssociety.org/What-is-MS/Types-of-MS/Primary-progressive-MS. Accessed August 10, 2018.
National Institutes of Health website. What is high-risk pregnancy. https://www.nichd.nih.gov/health/topics/pregnancy/conditioninfo/high-risk. Accessed August 10, 2018.
Alroughani R, Alowayesh MS, Ahmed SF, Behbehani R, Al-Hashel J. Relapse occurrence in women with multiple sclerosis during pregnancy in the new treatment era. Neurology. 2018;90:e840-e846.
Bove R, Alwan S, Friedman JM, et al. Management of multiple sclerosis during pregnancy and the reproductive years: a systematic review. Obstet Gynecol. 2014;124:1157-1168.
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Vaughn C, Bushra A, Kolb C, Weinstock-Guttman B. An update on the use of disease-modifying therapy in pregnant patients with multiple sclerosis. CNS Drugs. 2018;32:161-178.

CME / CE

Pregnancy in MS: Balancing the Risks

Authors: Patricia K. Coyle, MD; Bianca Weinstock-Guttman, MD
CME / CE Released: 9/18/2018
THIS ACTIVITY HAS EXPIRED
Valid for credit through: 9/18/2019

Target Audience and Goal Statement

This activity is intended for neurologists, primary care physicians, obstetricians and gynecologists, and nurses.

The goal of this activity is to review the impact of pregnancy on multiple sclerosis (MS), conception planning, and the treatment of MS during pregnancy.

Upon completion of this activity, participants will:

Have increased knowledge regarding the data on the use of disease-modifying therapies (DMTs) in MS during pregnancy
Have greater competence related to development of a treatment plan for MS during pregnancy

Disclosures

As an organization accredited by the ACCME, Medscape, LLC, requires everyone who is in a position to control the content of an education activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines "relevant financial relationships" as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner, that could create a conflict of interest.

Medscape, LLC, encourages Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.

Moderator

Patricia K. Coyle, MD

Professor and Vice Chair of Clinical Affairs
Director, MS Comprehensive Care Center
Stony Brook University Medical Center
Stony Brook, New York

Disclosures

Disclosure: Patricia K. Coyle, MD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Accordant; Acorda Therapeutics; Bayer HealthCare; Biogen; Celgene Corporation; Genentech, Inc.; Novartis Pharmaceuticals Corporation; Sanofi Genzyme Corporation; Serono; Teva Pharmaceuticals USA
Received grants for clinical research from: Actelion Pharmaceuticals, Ltd; Genentech, Inc.; MedDay; Novartis Pharmaceuticals Corporation

Dr Coyle does not intend to discuss off-label uses of drugs, mechanical devices, biologics, or diagnostics approved by the FDA for use in the United States.

Dr Coyle does not intend to discuss investigational drugs, mechanical devices, biologics, or diagnostics not approved by the FDA for use in the United States.

Panelist

Bianca Weinstock-Guttman, MD

Professor of Neurology
Jacobs School of Medicine & Biomedical Sciences
Department of Neurology
University of Buffalo
Buffalo, New York

Disclosures

Disclosure: Bianca Weinstock-Guttman, MD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Biogen; Genentech, Inc.; Novartis Pharmaceuticals Corporation; Sanofi; Teva Pharmaceuticals USA
Served as a speaker or a member of a speakers bureau for: Biogen; Genentech, Inc.; Novartis Pharmaceuticals Corporation; Sanofi; Teva Pharmaceuticals USA
Received grants for clinical research from: Biogen; Novartis Pharmaceuticals Corporation; Sanofi; Serono

Dr Weinstock-Guttman does intend to discuss off-label uses of drugs, mechanical devices, biologics, or diagnostics approved by the FDA for use in the United States.

Dr Weinstock-Guttman does not intend to discuss investigational drugs, mechanical devices, biologics, or diagnostics not approved by the FDA for use in the United States.

Steering Committee

Stephen Krieger, MD

Associate Professor of Neurology
Director
Neurology Residency Program
Icahn School of Medicine at Mount Sinai
New York, New York

Disclosures

Disclosure: Stephen Krieger, MD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Acorda Therapeutics; Bayer HealthCare; Biogen; EMD Serono, Inc.; Genentech, Inc.; Genzyme Corporation; Mallinckrodt Pharmaceuticals; MedDay Pharmaceuticals; Novartis Pharmaceuticals Corporation; Teva Pharmaceuticals USA; TG Therapeutics
Served as a speaker or a member of a speakers bureau for: Biogen; Genentech, Inc.

Patricia K. Coyle, MD

Disclosures

As listed above.

Anne H. Cross, MD

Professor of Neurology
Washington University School of Medicine
St. Louis, Missouri

Disclosures

Disclosure: Anne H. Cross, MD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Biogen; EMD Serono, Inc.; Novartis Pharmaceuticals Corporation; Genentech, Inc.; Genzyme Corporation; Sanofi
Received grants for clinical research from: Genentech, Inc.

Gavin Giovannoni, MBBCh, PhD

Professor and Chair of Neurology
Barts and The London School of Medicine and Dentistry
London, United Kingdom

Disclosures

Disclosure: Gavin Giovannoni, MBBCh, PHD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: AbbVie Inc.; Bayer HealthCare; Biogen; Canbex Therapeutics Ltd.; Eisai Inc.; Elan; Five Prime Therapeutics; Genzyme Corporation; Genentech, Inc.; GlaxoSmithKline; GW Pharma; Ironwood Pharmaceuticals, Inc.; Merck & Co., Inc.; Merck Serono; Novartis Pharmaceuticals Corporation; Pfizer Inc.; Roche Holding AG; Sanofi-Aventis; Synthon; Teva Pharmaceuticals USA; Vertex Pharmaceuticals Incorporated

Thomas P. Leist, MD, PhD

Professor of Neurology
Thomas Jefferson University
Philadelphia, Pennsylvania

Disclosures

Disclosure: Thomas P. Leist, MD, PhD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Teva Pharmaceuticals USA; Novartis Pharmaceuticals Corporation; Biogen; Genzyme Corporation; EMD Serono, Inc.; Genentech, Inc.
Served as a speaker or a member of a speakers bureau for: Teva Pharmaceuticals USA; Novartis Pharmaceuticals Corporation; Biogen
Received grants for clinical research from: Chugai Pharmaceutical Co.; Alkermes, Inc.; Novartis Pharmaceuticals Corporation; Biogen; Genzyme Corporation; Actelion Pharmaceuticals, Ltd

Claire Riley, MD

Assistant Professor of Neurology
Medical Director
Columbia MS Center
Columbia University Irving Medical Center
New York, New York

Disclosures

Disclosure: Claire Riley, MD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Celgene Corporation; Teva Pharmaceuticals USA

Editors

Catherine Friederich Murray

Scientific Director, Medscape, LLC

Disclosures

Disclosure: Catherine Friederich Murray has disclosed no relevant financial relationships.

Lisa Foulke

Associate Scientific Director, Medscape, LLC

Disclosures

Disclosure: Disclosure Lisa Foulke has disclosed no relevant financial relationships.

CME Reviewer / Nurse Planner

Amy Bernard, MS, BSN, RN-BC, CHCP

Lead Nurse Planner, Medscape, LLC

Disclosures

Disclosure: Amy Bernard, MS, BSN, RN-BC, CHCP, has disclosed no relevant financial relationships.

Peer Reviewer

This activity has been peer reviewed and the reviewer has disclosed no relevant financial relationships.

Accreditation Statements

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For Physicians

Medscape, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Medscape, LLC staff have disclosed that they have no relevant financial relationships.

Contact This Provider

For Nurses

Awarded 0.25 contact hour(s) of continuing nursing education for RNs and APNs; 0.25 contact hours are in the area of pharmacology.

Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]

Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

Follow these steps to earn CME/CE credit*:

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Study the educational content online or printed out.
Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

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From Medscape Education Neurology & Neurosurgery

CME / CE

Pregnancy in MS: Balancing the Risks

Authors: Patricia K. Coyle, MD; Bianca Weinstock-Guttman, MDFaculty and Disclosures

THIS ACTIVITY HAS EXPIRED

CME / CE Released: 9/18/2018

Valid for credit through: 9/18/2019

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References

Faculty and Disclosures

Moderator

Patricia K. Coyle, MD

Panelist

Bianca Weinstock-Guttman, MD

Steering Committee

Stephen Krieger, MD

Patricia K. Coyle, MD

Anne H. Cross, MD

Gavin Giovannoni, MBBCh, PhD

Thomas P. Leist, MD, PhD

Claire Riley, MD

Editors

Catherine Friederich Murray

Lisa Foulke

CME Reviewer / Nurse Planner

Amy Bernard, MS, BSN, RN-BC, CHCP

Peer Reviewer

CME / CE

Pregnancy in MS: Balancing the Risks

Target Audience and Goal Statement

Disclosures

Moderator

Patricia K. Coyle, MD

Panelist

Bianca Weinstock-Guttman, MD

Steering Committee

Stephen Krieger, MD

Patricia K. Coyle, MD

Anne H. Cross, MD

Gavin Giovannoni, MBBCh, PhD

Thomas P. Leist, MD, PhD

Claire Riley, MD

Editors

Catherine Friederich Murray

Lisa Foulke

CME Reviewer / Nurse Planner

Amy Bernard, MS, BSN, RN-BC, CHCP

Peer Reviewer

Accreditation Statements

For Physicians

For Nurses

Instructions for Participation and Credit

Pregnancy in MS: Balancing the Risks

Downloadable PDF