You are leaving Medscape Education
Cancel Continue
Log in to save activities Your saved activities will show here so that you can easily access them whenever you're ready. Log in here CME & Education Log in to keep track of your credits.
 

Table. Parameters used in relative risk calculations for ehrlichiosis and Lyme disease, by vector, Monmouth County, New Jersey, USA*  

Parameter Ixodes scapularis Amblyomma americanum
Relative abundance of each species CIS  = 38.32 CAA  = 61.68
Adults Nymphs Adults Nymphs
Relative abundance of each life stage CIS. D = 19.96 CIS. N = 80.04 CAA. D = 35.34 CAA. N  = 64.66
Infection rates per life stage IIS. D = 39.87 IIS. N = 23.3 IAA. D = 11.7 IAA. N = 9.04
Infection rates, weighted IIS = 26.60 IAA = 9.98

Table. Parameters used in relative risk calculations for ehrlichiosis and Lyme disease, by vector, Monmouth County, New Jersey, USA*

*Values are in percentages. Relative abundances (denoted by CX ) are derived from specimens submitted to the Monmouth County Mosquito Control Division’s tick identification and testing service during peak Lyme disease transmission season (May–August) and during a 10-year period (2006–2015). Infection rates of I. scapularis ticks with Borrelia burgdorferi (IIS ) also from passive surveillance program. Infection rates of A. americanum ticks (IAA ) encompass both Ehrlichia chaffeensis and E. ewingii (accounting for co-infection).

CME

Relative Risk for Ehrlichiosis and Lyme Disease in an Area Where Vectors for Both Are Sympatric, New Jersey, USA

  • Authors: Andrea Egizi, PhD, Nina H. Fefferman, PhD, Robert A. Jordan, PhD
  • CME Released: 5/11/2017
  • THIS ACTIVITY HAS EXPIRED FOR CREDIT
  • Valid for credit through: 5/11/2018
Start Activity


Target Audience and Goal Statement

This activity is intended for primary care physicians, infectious disease specialists, and other physicians who care for patients at risk for tick-borne illnesses.

The goal of this activity is to compare the prevalence of ehrlichiosis vs Lyme disease based on analytical models and case reports to public health agencies.

Upon completion of this activity, participants will be able to:

  1. Analyze the clinical presentation of ehrlichiosis
  2. Compare the vectors of ehrlichiosis vs Lyme disease
  3. Distinguish the ratio of ehrlichiosis to Lyme disease using a mathematical model
  4. Compare predicted rates of ehrlichiosis with actual reported rates of illness


Disclosures

As an organization accredited by the ACCME, Medscape, LLC, requires everyone who is in a position to control the content of an education activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines "relevant financial relationships" as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner, that could create a conflict of interest.

Medscape, LLC, encourages Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.


Authors

  • Andrea Egizi, PhD

    Monmouth County Mosquito Control Division, Tinton Falls, New Jersey, USA; Rutgers University, New Brunswick, New Jersey, USA

    Disclosures

    Disclosure: Andrea Egizi, PhD, has disclosed no relevant financial relationships.

  • Nina H. Fefferman, PhD

    University of Tennessee, Knoxville, Tennessee, USA; Rutgers University, New Brunswick, New Jersey, USA

    Disclosures

    Disclosure: Nina H. Fefferman, PhD, has disclosed the following relevant financial relationships:
    Owns stock, stock options, or bonds from: VIVUS, Inc.

  • Robert A. Jordan, PhD

    Monmouth County Mosquito Control Division, Tinton Falls, New Jersey, USA; Rutgers University, New Brunswick, New Jersey, USA

    Disclosures

    Disclosure: Robert A. Jordan, PhD, has disclosed no relevant financial relationships.

Editor

  • Jude Rutledge, BA

    Copyeditor, Emerging Infectious Diseases

    Disclosures

    Disclosure: Jude Rutledge, BA, has disclosed no relevant financial relationships.

CME Author

  • Charles P. Vega, MD

    Health Sciences Clinical Professor, UC Irvine Department of Family Medicine; Associate Dean for Diversity and Inclusion, UC Irvine School of Medicine, Irvine, California

    Disclosures

    Disclosure: Charles P. Vega, MD, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: McNeil Consumer Healthcare
    Served as a speaker or a member of a speakers bureau for: Shire Pharmaceuticals

CME Reviewer

  • Robert Morris, PharmD

    Associate CME Clinical Director, Medscape, LLC

    Disclosures

    Disclosure: Robert Morris, PharmD, has disclosed no relevant financial relationships.


Accreditation Statements




In support of improving patient care, this activity has been planned and implemented by Medscape, LLC and Emerging Infectious Diseases. Medscape, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    For Physicians

  • Medscape, LLC designates this Journal-based CME activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Medscape, LLC staff have disclosed that they have no relevant financial relationships.

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. We encourage you to complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME

Relative Risk for Ehrlichiosis and Lyme Disease in an Area Where Vectors for Both Are Sympatric, New Jersey, USA: Results

processing....

Results

The relative risk for ehrlichiosis cases compared to Lyme disease was calculated as risk = (61.68 × 9.98 × 1)/(38.32 × 26.61 × 1) = 0.604. These numbers mean that we should expect to see ehrlichiosis cases occur 0.604 times as often as Lyme disease cases.

Enlarge

Figure 2. Number of observed versus expected ehrlichiosis cases, Monmouth County, New Jersey, USA, 2014. Expected values calculated by using number of observed Lyme disease cases as benchmark.

In 2014, a total of 439 cases of Lyme disease were reported in Monmouth County.[22] By using the risk estimates described, we would expect there to be ≥265 cases of ehrlichiosis, >2 orders of magnitude higher than the number of cases actually observed (Figure 2).